23andme-converter: code_size: 23555 commercial_warning: null data_size: 60 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.4: null 1.1.0: null 1.1.1: null 1.1.2: null 1.2.0: null 1.2.1: null 1.2.2: null 1.3.0: null 1.3.1: null 1.4.0: null 1.5.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: 1.0.2 1.0.4: 1.0.2 1.1.0: 1.0.2 1.1.1: 1.0.2 1.1.2: 1.0.2 1.2.0: 1.0.2 1.2.1: 1.0.2 1.2.2: 1.0.2 1.3.0: 1.3.0 1.3.1: 1.3.0 1.4.0: 1.3.0 1.5.0: 1.3.0 datasource: null description: Allows user to input files in 23andMe format. In both the graphical interface and command line usage, file format will be automatically detected after this converter is installed. developer: citation: '' email: kmoad@insilico.us.com name: Kyle Moad organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: false latest_version: 1.5.0 publish_time: 2019-05-22T19:12:35.744619+0000 requires: - varmeta - vcfinfo>=1.1.5 - hg19wgs size: 23615 tags: - input/output title: 23andMe Converter type: converter versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.4 - 1.1.0 - 1.1.1 - 1.1.2 - 1.2.0 - 1.2.1 - 1.2.2 - 1.3.0 - 1.3.1 - 1.4.0 - 1.5.0 abraom: code_size: 10969 commercial_warning: 'For academic use only. ' data_size: 113610752 data_sources: 1.0.0: null data_versions: 1.0.0: 1.0.0 datasource: null description: Exomic allele frequencies of an elderly cohort of Brazilians in the ABraOM database developer: citation: "Naslavsky, Yamamoto et al. (2017). Exomic variants of an elderly cohort\ \ of Brazilians in the ABraOM database. Human Mutation, 38(7), 751\xE2\u20AC\ \u201C763." email: '' name: Naslavsky, Yamamoto et al. organization: NCBI Hackathon 2019 website: http://abraom.ib.usp.br/ groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2020-08-21T18:27:35.853157+0000 requires: null size: 113621721 tags: - allele frequency title: ABRaOM type: annotator versions: - 1.0.0 aggregator: code_size: 32464 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.2: null data_versions: 1.0.0: null 1.0.2: null datasource: null description: Aggregator developer: citation: '' email: kmoad@insilico.us.com name: Kyle Moad organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.0.2 publish_time: '2018-11-20T22:16:49.000000' requires: null size: 32464 tags: null title: Aggregator type: aggregator versions: - 1.0.0 - 1.0.2 alfa: code_size: 120291 commercial_warning: null data_size: 19821930500 data_sources: 1.0.0: 2020.02.29 data_versions: 1.0.0: 1.0.0 datasource: 2020.02.29 description: The goal of the ALFA project is to make frequency data from over 1M dbGaP subjects open-access in future releases to facilitate discoveries and interpretations of common and rare variants with biological impacts or causing diseases. developer: citation: 'L. Phan, Y. Jin, H. Zhang, W. Qiang, E. Shekhtman, D. Shao, D. Revoe, R. Villamarin, E. Ivanchenko, M. Kimura, Z. Y. Wang, L. Hao, N. Sharopova, M. Bihan, A. Sturcke, M. Lee, N. Popova, W. Wu, C. Bastiani, M. Ward, J. B. Holmes, V. Lyoshin, K. Kaur, E. Moyer, M. Feolo, and B. L. Kattman. "ALFA: Allele Frequency Aggregator." National Center for Biotechnology Information, U.S. National Library of Medicine, 10 Mar. 2020, www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/.' email: support@cravat.us name: NCBI organization: NCBI website: https://www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/#background groups: - alfa_group has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2021-01-12T19:35:24.767374+0000 requires: - alfa_group size: 19822050791 tags: - allele frequency title: 'ALFA: Allele Frequency Aggregator' type: annotator versions: - 1.0.0 alfa_african: code_size: 121829 commercial_warning: null data_size: 23177492484 data_sources: 1.0.0: 2020.02.29 data_versions: 1.0.0: 1.0.0 datasource: 2020.02.29 description: The goal of the ALFA project is to make frequency data from over 1M dbGaP subjects open-access in future releases to facilitate discoveries and interpretations of common and rare variants with biological impacts or causing diseases. developer: citation: 'L. Phan, Y. Jin, H. Zhang, W. Qiang, E. Shekhtman, D. Shao, D. Revoe, R. Villamarin, E. Ivanchenko, M. Kimura, Z. Y. Wang, L. Hao, N. Sharopova, M. Bihan, A. Sturcke, M. Lee, N. Popova, W. Wu, C. Bastiani, M. Ward, J. B. Holmes, V. Lyoshin, K. Kaur, E. Moyer, M. Feolo, and B. L. Kattman. "ALFA: Allele Frequency Aggregator." National Center for Biotechnology Information, U.S. National Library of Medicine, 10 Mar. 2020, www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/.' email: support@cravat.us name: NCBI organization: NCBI website: https://www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/#background groups: - alfa_group has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2021-01-12T19:36:36.943153+0000 requires: - alfa_group size: 23177614313 tags: - allele frequency title: 'ALFA: Allele Frequency Aggregator African' type: annotator versions: - 1.0.0 alfa_asian: code_size: 122452 commercial_warning: null data_size: 24120875012 data_sources: 1.0.0: 2020.02.29 data_versions: 1.0.0: 1.0.0 datasource: 2020.02.29 description: The goal of the ALFA project is to make frequency data from over 1M dbGaP subjects open-access in future releases to facilitate discoveries and interpretations of common and rare variants with biological impacts or causing diseases. developer: citation: 'L. Phan, Y. Jin, H. Zhang, W. Qiang, E. Shekhtman, D. Shao, D. Revoe, R. Villamarin, E. Ivanchenko, M. Kimura, Z. Y. Wang, L. Hao, N. Sharopova, M. Bihan, A. Sturcke, M. Lee, N. Popova, W. Wu, C. Bastiani, M. Ward, J. B. Holmes, V. Lyoshin, K. Kaur, E. Moyer, M. Feolo, and B. L. Kattman. "ALFA: Allele Frequency Aggregator." National Center for Biotechnology Information, U.S. National Library of Medicine, 10 Mar. 2020, www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/.' email: support@cravat.us name: NCBI organization: NCBI website: https://www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/#background groups: - alfa_group has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2021-01-12T19:38:53.151457+0000 requires: - alfa_group size: 24120997464 tags: - allele frequency title: 'ALFA: Allele Frequency Aggregator Asian' type: annotator versions: - 1.0.0 alfa_european: code_size: 120349 commercial_warning: null data_size: 19817850884 data_sources: 1.0.0: 2020.02.29 data_versions: 1.0.0: 1.0.0 datasource: 2020.02.29 description: The goal of the ALFA project is to make frequency data from over 1M dbGaP subjects open-access in future releases to facilitate discoveries and interpretations of common and rare variants with biological impacts or causing diseases. developer: citation: 'L. Phan, Y. Jin, H. Zhang, W. Qiang, E. Shekhtman, D. Shao, D. Revoe, R. Villamarin, E. Ivanchenko, M. Kimura, Z. Y. Wang, L. Hao, N. Sharopova, M. Bihan, A. Sturcke, M. Lee, N. Popova, W. Wu, C. Bastiani, M. Ward, J. B. Holmes, V. Lyoshin, K. Kaur, E. Moyer, M. Feolo, and B. L. Kattman. "ALFA: Allele Frequency Aggregator." National Center for Biotechnology Information, U.S. National Library of Medicine, 10 Mar. 2020, www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/.' email: support@cravat.us name: NCBI organization: NCBI website: https://www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/#background groups: - alfa_group has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2021-01-12T19:40:14.130274+0000 requires: - alfa_group size: 19817971233 tags: - allele frequency title: 'ALFA: Allele Frequency Aggregator European' type: annotator versions: - 1.0.0 alfa_group: code_size: 101721 commercial_warning: null data_size: 0 data_sources: 1.0.0: 2020.02.29 data_versions: 1.0.0: null datasource: 2020.02.29 description: The goal of the ALFA project is to make frequency data from over 1M dbGaP subjects open-access in future releases to facilitate discoveries and interpretations of common and rare variants with biological impacts or causing diseases. developer: citation: 'L. Phan, Y. Jin, H. Zhang, W. Qiang, E. Shekhtman, D. Shao, D. Revoe, R. Villamarin, E. Ivanchenko, M. Kimura, Z. Y. Wang, L. Hao, N. Sharopova, M. Bihan, A. Sturcke, M. Lee, N. Popova, W. Wu, C. Bastiani, M. Ward, J. B. Holmes, V. Lyoshin, K. Kaur, E. Moyer, M. Feolo, and B. L. Kattman. "ALFA: Allele Frequency Aggregator." National Center for Biotechnology Information, U.S. National Library of Medicine, 10 Mar. 2020, www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/.' email: support@opencravat.org name: NCBI organization: NCBI website: https://www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/#background groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-12-17T20:45:37.554608+0000 requires: null size: 101721 tags: - allele frequency title: 'ALFA: Allele Frequency Aggregator' type: group versions: - 1.0.0 alfa_latin_american: code_size: 123448 commercial_warning: null data_size: 20335691780 data_sources: 1.0.0: 2020.02.29 data_versions: 1.0.0: 1.0.0 datasource: 2020.02.29 description: The goal of the ALFA project is to make frequency data from over 1M dbGaP subjects open-access in future releases to facilitate discoveries and interpretations of common and rare variants with biological impacts or causing diseases. developer: citation: 'L. Phan, Y. Jin, H. Zhang, W. Qiang, E. Shekhtman, D. Shao, D. Revoe, R. Villamarin, E. Ivanchenko, M. Kimura, Z. Y. Wang, L. Hao, N. Sharopova, M. Bihan, A. Sturcke, M. Lee, N. Popova, W. Wu, C. Bastiani, M. Ward, J. B. Holmes, V. Lyoshin, K. Kaur, E. Moyer, M. Feolo, and B. L. Kattman. "ALFA: Allele Frequency Aggregator." National Center for Biotechnology Information, U.S. National Library of Medicine, 10 Mar. 2020, www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/.' email: support@cravat.us name: NCBI organization: NCBI website: https://www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/#background groups: - alfa_group has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2021-01-12T19:41:58.454801+0000 requires: - alfa_group size: 20335815228 tags: - allele frequency title: 'ALFA: Allele Frequency Aggregator Latin American' type: annotator versions: - 1.0.0 alfa_other: code_size: 120329 commercial_warning: null data_size: 18854877188 data_sources: 1.0.0: 2020.02.29 data_versions: 1.0.0: 1.0.0 datasource: 2020.02.29 description: The goal of the ALFA project is to make frequency data from over 1M dbGaP subjects open-access in future releases to facilitate discoveries and interpretations of common and rare variants with biological impacts or causing diseases. developer: citation: 'L. Phan, Y. Jin, H. Zhang, W. Qiang, E. Shekhtman, D. Shao, D. Revoe, R. Villamarin, E. Ivanchenko, M. Kimura, Z. Y. Wang, L. Hao, N. Sharopova, M. Bihan, A. Sturcke, M. Lee, N. Popova, W. Wu, C. Bastiani, M. Ward, J. B. Holmes, V. Lyoshin, K. Kaur, E. Moyer, M. Feolo, and B. L. Kattman. "ALFA: Allele Frequency Aggregator." National Center for Biotechnology Information, U.S. National Library of Medicine, 10 Mar. 2020, www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/.' email: support@cravat.us name: NCBI organization: NCBI website: https://www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/#background groups: - alfa_group has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2021-01-12T19:43:40.045906+0000 requires: - alfa_group size: 18854997517 tags: - allele frequency title: 'ALFA: Allele Frequency Aggregator Others' type: annotator versions: - 1.0.0 allofus250k: code_size: 18509 commercial_warning: null data_size: 150660669440 data_sources: 7.1.0: Variant Annotation Table v7.1 7.1.1: Variant Annotation Table v7.1 data_versions: 7.1.0: 7.1.0 7.1.1: 7.1.1 datasource: Variant Annotation Table v7.1 description: Allele counts and frequencies stratified by calculated genetic ancestry groupings from the All of Us dataset; Variant Annotation Table v7.1 developer: citation: "Bick, A. G. et al. Genomic data in the All of Us Research Program.\ \ Nature 627, 340\u2013346 (2024)." email: mdawood@bcm.edu name: Moez Dawood organization: All of Us and the Baylor College of Medicine Human Genome Sequencing Center website: https://support.researchallofus.org/hc/en-us/articles/4615256690836-Variant-Annotation-Table groups: [] has_logo: true hidden: false latest_version: 7.1.1 publish_time: 2025-04-14T19:42:34.871230+0000 requires: null size: 150660687949 tags: - variants - allele frequency title: All of Us type: annotator versions: - 7.1.0 - 7.1.1 aloft: code_size: 118396 commercial_warning: null data_size: 450652164 data_sources: 1.0.0: v4.1a 1.1.0: v4.3a data_versions: 1.0.0: 1.0.0 1.1.0: 1.1.0 datasource: v4.3a description: ALoFT provides extensive annotations to putative loss-of-function variants (LoF) in protein-coding genes including functional, evolutionary and network features. developer: citation: Suganthi Balasubramanian, Yao Fu, Mayur Pawashe, Patrick McGillivray, Mike Jin, Jeremy Liu, Konrad J. Karczewski, Daniel G. MacArthur, and Mark Gerstein. "Using ALoFT to determine the impact of putative loss-of-function variants in protein-coding genes." Nature Communications 8 (2017). email: support@opencravat.org name: Gerstein Lab organization: Yale University website: http://aloft.gersteinlab.org/ groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2024-12-17T19:12:09.355640+0000 requires: - wgaloft size: 450770560 tags: - variants - variant effect prediction title: ALoFT type: annotator versions: - 1.0.0 - 1.1.0 alphamissense: code_size: 7333 commercial_warning: null data_size: 3992842240 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: null description: Variant pathogenicity scores from AlphaMissense developer: citation: 'J. Cheng et al., Science 381, eadg7492 (2023). DOI: 10.1126/science.adg7492' email: support@opencravat.org name: Jun Cheng et al. organization: Google DeepMind website: '' groups: [] has_logo: false hidden: false latest_version: 1.1.0 publish_time: 2024-02-16T20:52:16.543127+0000 requires: - wgalphamissense size: 3992849573 tags: - variant effect prediction - variants - clinical relevance title: AlphaMissense type: annotator versions: - 1.0.0 - 1.1.0 ancestrydna-converter: code_size: 35311 commercial_warning: null data_size: 60 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.1.0: null 1.1.1: null 1.1.2: null 1.2.0: null 1.2.1: null 1.2.2: null 1.3.0: null 1.3.1: null 1.4.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: 1.0.2 1.0.3: 1.0.2 1.0.4: 1.0.2 1.1.0: 1.0.2 1.1.1: 1.0.2 1.1.2: 1.0.2 1.2.0: 1.0.2 1.2.1: 1.0.2 1.2.2: 1.0.2 1.3.0: 1.3.0 1.3.1: 1.3.0 1.4.0: 1.3.0 datasource: null description: Allows user to input files in AncestryDNA format. In both the graphical interface and command line usage, file format will be automatically detected after this converter is installed. developer: citation: '' email: kmoad@insilico.us.com name: Kyle Moad organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: false latest_version: 1.4.0 publish_time: 2019-05-22T19:12:52.009274+0000 requires: - varmeta - vcfinfo>=1.1.5 - hg19wgs size: 35371 tags: - input/output title: AncestryDNA Converter type: converter versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.1.0 - 1.1.1 - 1.1.2 - 1.2.0 - 1.2.1 - 1.2.2 - 1.3.0 - 1.3.1 - 1.4.0 arrvars: code_size: 129240 commercial_warning: null data_size: 2000900 data_sources: 1.0.0: January 2020 1.1.0: January 2020 1.2.0: January 2020 data_versions: 1.0.0: 1.0.0 1.1.0: 1.1.0 1.2.0: 1.2.0 datasource: January 2020 description: Examines variants associated with arrhythmia diseases such as Brugada Syndrome and Long QT Syndrome. developer: citation: 'Kroncke, Brett M., et al. "A Bayesian method to estimate variant-induced disease penetrance." PLoS genetics 16.6 (2020): e1008862.' email: support@opencravat.org name: Vanderbilt University Medical Center for Arrhythmia Research and Therapeutics organization: Vanderbilt University Medical Center for Arrhythmia Research and Therapeutics website: https://oates.app.vumc.org/vancart/ groups: [] has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-17T20:17:22.944577+0000 requires: null size: 2130140 tags: - clinical relevance - variant effect prediction - variants title: Arrhythmia Channelopathy Variants type: annotator versions: - 1.0.0 - 1.1.0 - 1.2.0 bayesdel: code_size: 13652 commercial_warning: null data_size: 5765896196 data_sources: 1.0.0: dbNSFP v4.7a 1.0.1: dbNSFP v4.7a 1.1.0: dbNSFP v4.7a data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.1.0: 1.0.0 datasource: dbNSFP v4.7a description: BayesDel is a deleteriousness meta-score predictor with pre-computed scores for missense variants. developer: citation: "Feng, Bing-Jian. \u201CPERCH: A Unified Framework for Disease Gene\ \ Prioritization.\u201D Human mutation vol. 38,3 (2017): 243-251. doi:10.1002/humu.23158" email: support@opencravat.org name: Bing-Jian Feng organization: University of Utah website: http://bjfenglab.org/ groups: [] has_logo: false hidden: false latest_version: 1.1.0 publish_time: 2024-05-09T17:21:34.242527+0000 requires: - wgbayesdel size: 5765909848 tags: - clinical relevance - variant effect prediction - variants title: BayesDel type: annotator versions: - 1.0.0 - 1.0.1 - 1.1.0 biogrid: code_size: 191674 commercial_warning: null data_size: 131526656 data_sources: 3.5.167: 4.0.0 3.5.168: v3.5.167 3.5.169: v3.5.167 3.5.170: v3.5.167 3.5.171: v3.5.167 3.5.172: v3.5.167 3.5.173: v3.5.167 3.6.0: v3.5.167 3.7.0: v4.4.197 3.8.0: v4.4.216 3.9.1: v4.4.230 3.9.2: v4.4.237 3.9.3: v4.4.247 data_versions: 3.5.167: 3.5.167 3.5.168: 3.5.167 3.5.169: 3.5.167 3.5.170: 3.5.167 3.5.171: 3.5.167 3.5.172: 3.5.167 3.5.173: 3.5.167 3.6.0: 3.6.0 3.7.0: 3.7.0 3.8.0: 3.8.0 3.9.1: 3.9.1 3.9.2: 3.9.2 3.9.3: 3.9.3 datasource: v4.4.247 description: Comprehensive interaction repository developer: citation: 'Oughtred R, Stark C, Breitkreutz BJ, et al. (2018). The BioGRID interaction database: 2019 update. Nucleic Acids Res. 47(D1):D529-D541.' email: support@opencravat.org name: BioGRID organization: BioGRID website: https://thebiogrid.org/ groups: [] has_logo: true hidden: false latest_version: 3.9.3 publish_time: 2025-07-08T15:09:47.376489+0000 requires: - wgbiogrid size: 131718330 tags: - genes title: BioGRID type: annotator versions: - 3.5.167 - 3.5.168 - 3.5.169 - 3.5.170 - 3.5.171 - 3.5.172 - 3.5.173 - 3.6.0 - 3.7.0 - 3.8.0 - 3.9.1 - 3.9.2 - 3.9.3 brca1_func_assay: code_size: 124612 commercial_warning: 'For commercial use, contact lstarita@uw.edu. ' data_size: 137390 data_sources: 2018.10.4: null 2018.12.20: null 2018.12.26: null 2019.03.20: dbNSFP v4.0b1 2019.03.21: 2018.04.05 2019.05.13: 2018.04.05 2019.1.23: null 2019.1.231: dbNSFP v4.0b1 2019.2.6: dbNSFP v4.0b1 data_versions: 2018.10.4: 2018.10.4 2018.12.20: 2018.10.4 2018.12.26: 2018.10.4 2019.03.20: 2018.10.4 2019.03.21: 2018.10.4 2019.05.13: 2018.10.4 2019.1.23: 2018.10.4 2019.1.231: 2018.10.4 2019.2.6: 2018.10.4 datasource: 2018.04.05 description: Impact of BRCA1 missense variants on protein function as determined by multiplex homology-directed DNA repair assay developer: citation: Findlay, G.M., Daza, R.M., Martin, B., Zhang, M.D., Leith, A.P., Gasperini, M.J., Janizek, J.D., Huang, X., Starita, L.M., & Shendure, J. (2018). Accurate classification of BRCA1 variants with saturation genome editing. Nature, 1-6. email: support@opencravat.org name: Lea Starita organization: Starita Lab website: http://staritalab.org/ groups: [] has_logo: true hidden: false latest_version: 2019.05.13 publish_time: 2019-03-23T20:11:20.673046+0000 requires: - wgbrca1_func_assay size: 262002 tags: - variants - cancer - functional studies title: BRCA1 Saturation Genome Editing Scores type: annotator versions: - 2018.10.4 - 2018.12.20 - 2018.12.26 - 2019.1.23 - 2019.1.231 - 2019.2.6 - 2019.03.20 - 2019.03.21 - 2019.05.13 cadd: code_size: 132596 commercial_warning: CADD scores are freely available for all non-commercial applications.If you are planning on using them in a commercial application, please obtain a license. data_size: 86595748694 data_sources: 1.0.0: v1.6 1.0.1: v1.6 1.1.0: v1.6 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.1.0: 1.0.0 datasource: v1.6 description: CADD is a tool for scoring the deleteriousness of single nucleotide variants in the human genome. developer: citation: 'Rentzsch P, Witten D, Cooper GM, Shendure J, Kircher M. CADD: predicting the deleteriousness of variants throughout the human genome. Nucleic Acids Res.2018 Oct 29. doi: 10.1093/nar/gky1016. PubMed PMID: 30371827.' email: support@opencravat.org name: Martin Kircher organization: Shendure Lab, University of Washington website: https://cadd.gs.washington.edu/ groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2021-06-14T15:18:12.657184+0000 requires: - wgcadd size: 86595881290 tags: - variant effect prediction - variants - clinical relevance title: CADD type: annotator versions: - 1.0.0 - 1.0.1 - 1.1.0 cadd_exome: code_size: 258337 commercial_warning: CADD scores are freely available for all non-commercial applications. If you are planning on using them in a commercial application, please obtain a license. data_size: 6811920384 data_sources: 1.6.0: '1.6' 1.6.1: '1.6' 1.7.0: '1.6' data_versions: 1.6.0: 1.6.0 1.6.1: 1.6.0 1.7.0: 1.6.0 datasource: '1.6' description: CADD is a tool for scoring the deleteriousness of single nucleotide variants in the human genome. developer: citation: 'Rentzsch P, Witten D, Cooper GM, Shendure J, Kircher M. CADD: predicting the deleteriousness of variants throughout the human genome. Nucleic Acids Res. 2018 Oct 29. doi: 10.1093/nar/gky1016. PubMed PMID: 30371827.' email: support@opencravat.org name: Martin Kircher organization: Shendure Lab, University of Washington website: https://cadd.gs.washington.edu/ groups: [] has_logo: true hidden: false latest_version: 1.7.0 publish_time: 2020-05-18T16:24:17.165379+0000 requires: - wgcadd_exome size: 6812178721 tags: - variant effect prediction - variants - clinical relevance title: CADD Exome type: annotator versions: - 1.6.0 - 1.6.1 - 1.7.0 cancer_genome_interpreter: code_size: 348044 commercial_warning: Freely available for non-commercial use. data_size: 198660 data_sources: 1.0.0: 2018.01.17 1.1.0: 2018.01.17 1.2.0: 2018.01.17 1.3.0: 2018.01.17 data_versions: 1.0.0: 1.0.0 1.1.0: 1.1.0 1.2.0: 1.2.0 1.3.0: 1.3.0 datasource: 2018.01.17 description: Flags validated oncogenic alterations and genomic biomarkers of drug response, while predicting cancer drivers among mutations of unknown significance. developer: citation: 'Tamborero, David, et al. "Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations." Genome medicine 10.1 (2018): 25.' email: support@opencravat.org name: Global Alliance for Genomics and Health organization: Global Alliance for Genomics and Health website: https://www.cancergenomeinterpreter.org/biomarkers groups: [] has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-11-10T20:38:36.004553+0000 requires: - wgcancer_genome_interpreter size: 546704 tags: - cancer - clinical relevance - genes - variant effect prediction title: Cancer Genome Interpreter type: annotator versions: - 1.0.0 - 1.1.0 - 1.2.0 - 1.3.0 cancer_hotspots: code_size: 29681 commercial_warning: null data_size: 223236 data_sources: 1.0.0: December 2017 1.1.0: December 2017 1.2.0: December 2017 1.2.1: December 2017 data_versions: 1.0.0: 1.0.0 1.1.0: 1.1.0 1.2.0: 1.2.0 1.2.1: 1.2.0 datasource: December 2017 description: A resource for statistically significant mutations in cancer. developer: citation: Chang et al., Accelerating discovery of functional mutant alleles in cancer. Cancer Discovery, 10.1158/2159-8290.CD-17-0321 (2017). email: support@opencravat.org name: Memorial Sloan Kettering Cancer Center organization: Memorial Sloan Kettering Cancer Center website: https://www.cancerhotspots.org/ groups: [] has_logo: true hidden: false latest_version: 1.2.1 publish_time: 2020-08-17T15:24:05.845210+0000 requires: - wgcancer_hotspots size: 252917 tags: - cancer - variants title: Cancer Hotspots type: annotator versions: - 1.0.0 - 1.1.0 - 1.2.0 - 1.2.1 cardioboost: code_size: 33211 commercial_warning: null data_size: 18155524 data_sources: 1.0.0: v2.1 data_versions: 1.0.0: 1.0.0 datasource: v2.1 description: Predicts pathogenicity of missense variants for inherited cardiac conditions developer: citation: Zhang, Xiaolei, et al. "Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions." bioRxiv (2020). email: support@opencravat.org name: CardioBoost organization: CardioBoost website: https://www.cardiodb.org/cardioboost/ groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-12-17T19:19:44.376000+0000 requires: null size: 18188735 tags: - clinical relevance - variant effect prediction - variants title: CardioBoost type: annotator versions: - 1.0.0 casecontrol: code_size: 31049 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null 1.2.0: null data_versions: 1.0.0: null 1.1.0: null 1.2.0: null datasource: null description: Performs case-control analysis on cohorts developer: citation: '' email: support@opencravat.org name: Kyle Moad organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-12-16T22:43:25.996954+0000 requires: - wgcasecontrolsummary - wgcasecontrols size: 31049 tags: null title: Case-Control type: postaggregator versions: - 1.0.0 - 1.1.0 - 1.2.0 ccr: code_size: 73170 commercial_warning: null data_size: 7923716 data_sources: 1.0.0: December 2018 data_versions: 1.0.0: 1.0.0 datasource: December 2018 description: The constrained coding regions model (CCR) uses the Genome Aggregation Database to reveal regions of protein coding genes that are likely to be under potentially purifiying selection. developer: citation: Havrilla, J.M., Pedersen, B.S., Layer, R.M. & Quinlan, A.R. A map of constrained coding regions in the human genome. Nature Genetics (2018). doi:10.1038/s41588-018-0294-6 email: support@opencravat.org name: James M. Havrilla organization: University of Utah website: https://s3.us-east-2.amazonaws.com/ccrs/ccr.html groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-12-17T19:19:44.412975+0000 requires: null size: 7996886 tags: - genes title: 'CCR: Constrained Coding Regions' type: annotator versions: - 1.0.0 ccre_screen: code_size: 265566 commercial_warning: null data_size: 77563908 data_sources: 1.0.0: 2019.1 1.0.1: 2019.1 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 datasource: 2019.1 description: SCREEN allows the user to explore Candidate cis-Regulatory Elements (cCREs) and investigate how these elements relate to other Encyclopedia annotations and raw ENCODE data. developer: citation: "ENCODE Project Consortium, Jill E. Moore, Michael J. Purcaro, Henry\ \ E. Pratt, Charles B. Epstein, Noam Shoresh, Jessika Adrian, et al. 2020. \u201C\ Expanded Encyclopaedias of DNA Elements in the Human and Mouse Genomes.\u201D\ \ Nature 583 (7818): 699\u2013710." email: support@opencravat.org name: Weng Lab organization: UMass Med, ENCODE Data Analysis Center website: https://screen.wenglab.org/ groups: [] has_logo: true hidden: false latest_version: 1.0.1 publish_time: 2020-10-15T19:40:16.488986+0000 requires: - wgccre_screen size: 77829474 tags: - non coding title: Candidate cis-Regulatory Elements by ENCODE (SCREEN) type: annotator versions: - 1.0.0 - 1.0.1 cedar: code_size: 57397 commercial_warning: null data_size: 8634239 data_sources: 1.0.0: null data_versions: 1.0.0: 1.0.0 datasource: null description: Annotations from the Cancer Epitope Database developer: citation: "Ko\u015Falo\u011Flu-Yal\xE7\u0131n Z, Blazeska N, Vita R, Carter H,\ \ Nielsen M, Schoenberger S, Sette A, Peters B. The Cancer Epitope Database\ \ and Analysis Resource (CEDAR). Nucleic Acids Res. 2023 Jan 6;51(D1):D845-D852.\ \ doi: 10.1093/nar/gkac902. PMID: 36250634; PMCID: PMC9825495" email: support@opencravat.org name: CEDAR Team organization: IEDB website: cedar.iedb.org groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-02-29T22:46:27.393580+0000 requires: null size: 8691636 tags: - variants - cancer title: CEDAR type: annotator versions: - 1.0.0 cgc: code_size: 156173 commercial_warning: For commercial use, contact cosmic@sanger.ac.uk data_size: 73728 data_sources: 85.0.0: v85 85.0.1: v85 85.0.10: '2019-03-23' 85.0.11: '2019-03-23' 85.0.12: '2019-03-23' 85.0.3: v85 85.0.5: v85 85.0.6: v85 85.0.7: v85 85.0.8: v85 85.0.9: v85 99.0.0: v99 data_versions: 85.0.0: 85.0.0 85.0.1: 85.0.0 85.0.10: 85.0.10 85.0.11: 85.0.10 85.0.12: 85.0.10 85.0.3: 85.0.3 85.0.5: 85.0.3 85.0.6: 85.0.3 85.0.7: 85.0.3 85.0.8: 85.0.3 85.0.9: 85.0.3 99.0.0: 99.0.0 datasource: v99 description: Cancer Gene Census annotation developer: citation: Futreal, P.A., Coin, L.J., Marshall, M., Down, T., Hubbard, T.L., Wooster, R., Rahman, N., & Stratton, M.R. (2004). A census of human cancer genes. Nature Reviews Cancer, 4, 177-183. email: support@opencravat.org name: Sanger Institute organization: Sanger Institute website: https://cancer.sanger.ac.uk/census groups: [] has_logo: true hidden: false latest_version: 99.0.0 publish_time: 2024-12-17T20:02:16.121002+0000 requires: - wgcgc size: 229901 tags: - genes - cancer title: Cancer Gene Census type: annotator versions: - 85.0.0 - 85.0.1 - 85.0.3 - 85.0.5 - 85.0.6 - 85.0.7 - 85.0.8 - 85.0.9 - 85.0.10 - 85.0.11 - 85.0.12 - 99.0.0 cgd: code_size: 97647 commercial_warning: null data_size: 612356 data_sources: 1.0.0: 2021.02.09 1.0.1: 2021.02.09 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 datasource: 2021.02.09 description: A manually curated database of conditions with known genetic causes, focusing on medically significant genetic data with available interventions. developer: citation: Solomon BD, Nguyen AD, Bear KA, Wolfsberg TG. Clinical Genomic Database. Proc Natl Acad Sci U S A. 2013 May 21. [Epub ahead of print] [PubMed]. email: support@opencravat.org name: NIH organization: NIH website: https://research.nhgri.nih.gov/CGD/ groups: [] has_logo: true hidden: false latest_version: 1.0.1 publish_time: 2021-06-10T18:21:10.186851+0000 requires: - wgcgd size: 710003 tags: - clinical relevance - genes title: 'CGD: Clinical Genomic Database' type: annotator versions: - 1.0.0 - 1.0.1 cgl: code_size: 451341 commercial_warning: null data_size: 14340 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: v2013.03.29 1.0.4: v2013.03.29 1.0.5: v2013.03.29 1.0.6: v2013.03.29 1.0.7: v2013.03.29 1.0.8: v2013.03.29 1.0.9: v2013.03.29 1.1.0: v2013.03.29 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.0.2: 1.0.0 1.0.3: 1.0.0 1.0.4: 1.0.0 1.0.5: 1.0.0 1.0.6: 1.0.0 1.0.7: 1.0.7 1.0.8: 1.0.7 1.0.9: 1.0.7 1.1.0: 1.1.0 datasource: v2013.03.29 description: Oncogenes and tumor supressor genes from Vogelstein et al. 2013 developer: citation: Vogelstein, B., Papadopoulos, N., Velculescu, V.E., Zhou, S., Diaz, L.A., & Kinzler, K.W. (2013). Cancer genome landscapes. Science, 339 6127, 1546-58. email: support@opencravat.org name: Bert Vogelstein organization: Johns Hopkins University website: http://science.sciencemag.org/content/339/6127/1546 groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2019-01-30T18:35:22.551632+0000 requires: null size: 465681 tags: - genes - cancer title: Cancer Gene Landscape type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.0.5 - 1.0.6 - 1.0.7 - 1.0.8 - 1.0.9 - 1.1.0 chasmplus: code_size: 110975 commercial_warning: Freely available for non-commercial use. data_size: 8040433475 data_sources: 1.0.1: null 1.0.10: v1.0.0 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: v1.0.0 1.0.6: v1.0.0 1.0.7: v1.0.0 1.0.8: v1.0.0 1.0.9: v1.0.0 1.1.0: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.2: 1.0.1 1.0.3: 1.0.1 1.0.4: 1.0.1 1.0.5: 1.0.1 1.0.6: 1.0.1 1.0.7: 1.0.1 1.0.8: 1.0.1 1.0.9: 1.0.1 1.1.0: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-01-30T18:35:31.269709+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8040544450 tags: - cancer - variant effect prediction title: CHASMplus type: annotator versions: - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.0.5 - 1.0.6 - 1.0.7 - 1.0.8 - 1.0.9 - 1.0.10 - 1.1.0 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_ACC: code_size: 33807 commercial_warning: null data_size: 8037283752 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:21:24.414464+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037317559 tags: - cancer - variant effect prediction title: CHASMplus ACC type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_ACC_mski: code_size: 34942 commercial_warning: null data_size: 89509 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:55:50.184277+0000 requires: - chasmplus_mski_group - chasmplus_ACC size: 124451 tags: - cancer - variant effect prediction title: CHASMplus ACC MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_BLCA: code_size: 30917 commercial_warning: null data_size: 8037357449 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:21:42.309414+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037388366 tags: - cancer - variant effect prediction title: CHASMplus BLCA type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_BLCA_mski: code_size: 32058 commercial_warning: null data_size: 141217 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:55:50.268897+0000 requires: - chasmplus_mski_group - chasmplus_BLCA size: 173275 tags: - cancer - variant effect prediction title: CHASMplus BLCA MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_BRCA: code_size: 31283 commercial_warning: null data_size: 8037136915 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:21:59.511102+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037168198 tags: - cancer - variant effect prediction title: CHASMplus BRCA type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_BRCA_mski: code_size: 32424 commercial_warning: null data_size: 121501 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:55:50.353857+0000 requires: - chasmplus_mski_group - chasmplus_BRCA size: 153925 tags: - cancer - variant effect prediction title: CHASMplus BRCA MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_CESC: code_size: 31766 commercial_warning: null data_size: 8037053864 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:22:16.689409+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037085630 tags: - cancer - variant effect prediction title: CHASMplus CESC type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_CESC_mski: code_size: 32890 commercial_warning: null data_size: 154467 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:55:50.438565+0000 requires: - chasmplus_mski_group - chasmplus_CESC size: 187357 tags: - cancer - variant effect prediction title: CHASMplus CESC MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_CHOL: code_size: 30588 commercial_warning: null data_size: 8037808854 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:22:33.864305+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037839442 tags: - cancer - variant effect prediction title: CHASMplus CHOL type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_CHOL_mski: code_size: 31721 commercial_warning: null data_size: 74240 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:55:50.523172+0000 requires: - chasmplus_mski_group - chasmplus_CHOL size: 105961 tags: - cancer - variant effect prediction title: CHASMplus CHOL MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_COAD: code_size: 33564 commercial_warning: null data_size: 8036642141 data_sources: 1.0.0: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.10: 1.0.0 1.0.11: 1.0.0 1.1.1: 1.0.0 1.1.2: 1.0.0 1.1.3: 1.0.0 1.1.4: 1.0.0 1.2.0: 1.0.0 1.3.0: 1.0.0 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:22:51.319119+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036675705 tags: - cancer - variant effect prediction title: CHASMplus COAD type: annotator versions: - 1.0.0 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_COAD_mski: code_size: 34708 commercial_warning: null data_size: 147896 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:55:50.608525+0000 requires: - chasmplus_mski_group - chasmplus_COAD size: 182604 tags: - cancer - variant effect prediction title: CHASMplus COAD MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_DLBC: code_size: 31322 commercial_warning: null data_size: 8037176419 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:23:09.674093+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037207741 tags: - cancer - variant effect prediction title: CHASMplus DLBC type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_DLBC_mski: code_size: 32443 commercial_warning: null data_size: 101345 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:55:50.693437+0000 requires: - chasmplus_mski_group - chasmplus_DLBC size: 133788 tags: - cancer - variant effect prediction title: CHASMplus DLBC MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_ESCA: code_size: 29945 commercial_warning: null data_size: 8037437057 data_sources: 1.0.0: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.10: 1.0.0 1.0.11: 1.0.0 1.1.1: 1.0.0 1.1.2: 1.0.0 1.1.3: 1.0.0 1.1.4: 1.0.0 1.2.0: 1.0.0 1.3.0: 1.0.0 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:23:26.881833+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037467002 tags: - cancer - variant effect prediction title: CHASMplus ESCA type: annotator versions: - 1.0.0 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_ESCA_mski: code_size: 31080 commercial_warning: null data_size: 142662 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:55:50.778260+0000 requires: - chasmplus_mski_group - chasmplus_ESCA size: 173742 tags: - cancer - variant effect prediction title: CHASMplus ESCA MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_GBM: code_size: 32894 commercial_warning: null data_size: 8036240284 data_sources: 1.0.0: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.10: 1.0.0 1.0.11: 1.0.0 1.1.1: 1.0.0 1.1.2: 1.0.0 1.1.3: 1.0.0 1.1.4: 1.0.0 1.2.0: 1.0.0 1.3.0: 1.0.0 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:23:44.080965+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036273178 tags: - cancer - variant effect prediction title: CHASMplus GBM type: annotator versions: - 1.0.0 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_GBM_mski: code_size: 34026 commercial_warning: null data_size: 146652 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:55:50.862920+0000 requires: - chasmplus_mski_group - chasmplus_GBM size: 180678 tags: - cancer - variant effect prediction title: CHASMplus GBM MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_HNSC: code_size: 34175 commercial_warning: null data_size: 8035834500 data_sources: 1.0.0: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.10: 1.0.0 1.0.11: 1.0.0 1.1.1: 1.0.0 1.1.2: 1.0.0 1.1.3: 1.0.0 1.1.4: 1.0.0 1.2.0: 1.0.0 1.3.0: 1.0.0 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:24:01.748559+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8035868675 tags: - cancer - variant effect prediction title: CHASMplus HNSC type: annotator versions: - 1.0.0 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_HNSC_mski: code_size: 35326 commercial_warning: null data_size: 156300 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:55:50.947145+0000 requires: - chasmplus_mski_group - chasmplus_HNSC size: 191626 tags: - cancer - variant effect prediction title: CHASMplus HNSC MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_KICH: code_size: 32685 commercial_warning: null data_size: 8037696338 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:24:18.962661+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037729023 tags: - cancer - variant effect prediction title: CHASMplus KICH type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_KICH_mski: code_size: 33830 commercial_warning: null data_size: 98797 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:55:51.032175+0000 requires: - chasmplus_mski_group - chasmplus_KICH size: 132627 tags: - cancer - variant effect prediction title: CHASMplus KICH MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_KIRC: code_size: 33074 commercial_warning: null data_size: 8036923777 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:28:30.820328+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036956851 tags: - cancer - variant effect prediction title: CHASMplus KIRC type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_KIRC_mski: code_size: 34112 commercial_warning: null data_size: 116061 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:55:51.117231+0000 requires: - chasmplus_mski_group - chasmplus_KIRC size: 150173 tags: - cancer - variant effect prediction title: CHASMplus KIRC MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_KIRP: code_size: 33136 commercial_warning: null data_size: 8037201556 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:24:36.235317+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037234692 tags: - cancer - variant effect prediction title: CHASMplus KIRP type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_KIRP_mski: code_size: 34254 commercial_warning: null data_size: 131866 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:55:51.202238+0000 requires: - chasmplus_mski_group - chasmplus_KIRP size: 166120 tags: - cancer - variant effect prediction title: CHASMplus KIRP MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_LAML: code_size: 30940 commercial_warning: null data_size: 8037264659 data_sources: 1.0.0: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.10: 1.0.0 1.0.11: 1.0.0 1.1.1: 1.0.0 1.1.2: 1.0.0 1.1.3: 1.0.0 1.1.4: 1.0.0 1.2.0: 1.0.0 1.3.0: 1.0.0 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:24:53.891396+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037295599 tags: - cancer - variant effect prediction title: CHASMplus LAML type: annotator versions: - 1.0.0 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_LAML_mski: code_size: 32043 commercial_warning: null data_size: 95577 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:41.018976+0000 requires: - chasmplus_mski_group - chasmplus_LAML size: 127620 tags: - cancer - variant effect prediction title: CHASMplus LAML MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_LGG: code_size: 32873 commercial_warning: null data_size: 8036810614 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:25:11.448773+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036843487 tags: - cancer - variant effect prediction title: CHASMplus LGG type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_LGG_mski: code_size: 34018 commercial_warning: null data_size: 129245 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:41.107624+0000 requires: - chasmplus_mski_group - chasmplus_LGG size: 163263 tags: - cancer - variant effect prediction title: CHASMplus LGG MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_LIHC: code_size: 31751 commercial_warning: null data_size: 8036551421 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:28:48.594286+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036583172 tags: - cancer - variant effect prediction title: CHASMplus LIHC type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_LIHC_mski: code_size: 32893 commercial_warning: null data_size: 137803 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:41.198017+0000 requires: - chasmplus_mski_group - chasmplus_LIHC size: 170696 tags: - cancer - variant effect prediction title: CHASMplus LIHC MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_LUAD: code_size: 32486 commercial_warning: null data_size: 8036329847 data_sources: 1.0.0: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.10: 1.0.0 1.0.11: 1.0.0 1.1.1: 1.0.0 1.1.2: 1.0.0 1.1.3: 1.0.0 1.1.4: 1.0.0 1.2.0: 1.0.0 1.3.0: 1.0.0 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:29:05.627192+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036362333 tags: - cancer - variant effect prediction title: CHASMplus LUAD type: annotator versions: - 1.0.0 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_LUAD_mski: code_size: 33625 commercial_warning: null data_size: 237014 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:41.286218+0000 requires: - chasmplus_mski_group - chasmplus_LUAD size: 270639 tags: - cancer - variant effect prediction title: CHASMplus LUAD MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_LUSC: code_size: 32649 commercial_warning: null data_size: 8036621615 data_sources: 1.0.0: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.10: 1.0.0 1.0.11: 1.0.0 1.1.1: 1.0.0 1.1.2: 1.0.0 1.1.3: 1.0.0 1.1.4: 1.0.0 1.2.0: 1.0.0 1.3.0: 1.0.0 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:29:22.870408+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036654264 tags: - cancer - variant effect prediction title: CHASMplus LUSC type: annotator versions: - 1.0.0 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_LUSC_mski: code_size: 33799 commercial_warning: null data_size: 161313 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:41.373913+0000 requires: - chasmplus_mski_group - chasmplus_LUSC size: 195112 tags: - cancer - variant effect prediction title: CHASMplus LUSC MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_MESO: code_size: 36056 commercial_warning: null data_size: 8037316310 data_sources: 1.0.0: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.10: 1.0.0 1.0.11: 1.0.0 1.1.1: 1.0.0 1.1.2: 1.0.0 1.1.3: 1.0.0 1.1.4: 1.0.0 1.2.0: 1.0.0 1.3.0: 1.0.0 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:29:39.953342+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037352366 tags: - cancer - variant effect prediction title: CHASMplus MESO type: annotator versions: - 1.0.0 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_MESO_mski: code_size: 37210 commercial_warning: null data_size: 145118 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:41.460872+0000 requires: - chasmplus_mski_group - chasmplus_MESO size: 182328 tags: - cancer - variant effect prediction title: CHASMplus MESO MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_OV: code_size: 31393 commercial_warning: null data_size: 8037071744 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:29:57.575185+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037103137 tags: - cancer - variant effect prediction title: CHASMplus OV type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_OV_mski: code_size: 32503 commercial_warning: null data_size: 110232 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:41.547877+0000 requires: - chasmplus_mski_group - chasmplus_OV size: 142735 tags: - cancer - variant effect prediction title: CHASMplus OV MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_PAAD: code_size: 32491 commercial_warning: null data_size: 8037643421 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:30:14.724908+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037675912 tags: - cancer - variant effect prediction title: CHASMplus PAAD type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_PAAD_mski: code_size: 33626 commercial_warning: null data_size: 148324 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:41.633978+0000 requires: - chasmplus_mski_group - chasmplus_PAAD size: 181950 tags: - cancer - variant effect prediction title: CHASMplus PAAD MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_PCPG: code_size: 32963 commercial_warning: null data_size: 8037188164 data_sources: 1.0.0: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.10: 1.0.0 1.0.11: 1.0.0 1.1.1: 1.0.0 1.1.2: 1.0.0 1.1.3: 1.0.0 1.1.4: 1.0.0 1.2.0: 1.0.0 1.3.0: 1.0.0 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:30:48.951257+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037221127 tags: - cancer - variant effect prediction title: CHASMplus PCPG type: annotator versions: - 1.0.0 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_PCPG_mski: code_size: 34098 commercial_warning: null data_size: 119444 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:41.720180+0000 requires: - chasmplus_mski_group - chasmplus_PCPG size: 153542 tags: - cancer - variant effect prediction title: CHASMplus PCPG MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_PRAD: code_size: 31897 commercial_warning: null data_size: 8036811406 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:31:06.661266+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036843303 tags: - cancer - variant effect prediction title: CHASMplus PRAD type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_PRAD_mski: code_size: 33039 commercial_warning: null data_size: 136578 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:41.811292+0000 requires: - chasmplus_mski_group - chasmplus_PRAD size: 169617 tags: - cancer - variant effect prediction title: CHASMplus PRAD MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_READ: code_size: 33583 commercial_warning: null data_size: 8036909675 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:31:23.976942+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036943258 tags: - cancer - variant effect prediction title: CHASMplus READ type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_READ_mski: code_size: 34742 commercial_warning: null data_size: 132802 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:41.897100+0000 requires: - chasmplus_mski_group - chasmplus_READ size: 167544 tags: - cancer - variant effect prediction title: CHASMplus READ MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_SARC: code_size: 35701 commercial_warning: null data_size: 8036919336 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:31:41.144509+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036955037 tags: - cancer - variant effect prediction title: CHASMplus SARC type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_SARC_mski: code_size: 36850 commercial_warning: null data_size: 107856 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:41.983461+0000 requires: - chasmplus_mski_group - chasmplus_SARC size: 144706 tags: - cancer - variant effect prediction title: CHASMplus SARC MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_SKCM: code_size: 36983 commercial_warning: null data_size: 8036679474 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:31:58.714812+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036716457 tags: - cancer - variant effect prediction title: CHASMplus SKCM type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_SKCM_mski: code_size: 38060 commercial_warning: null data_size: 136050 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:42.069732+0000 requires: - chasmplus_mski_group - chasmplus_SKCM size: 174110 tags: - cancer - variant effect prediction title: CHASMplus SKCM MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_STAD: code_size: 29962 commercial_warning: null data_size: 8036195924 data_sources: 1.0.0: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.10: 1.0.0 1.0.11: 1.0.0 1.1.1: 1.0.0 1.1.2: 1.0.0 1.1.3: 1.0.0 1.1.4: 1.0.0 1.2.0: 1.0.0 1.3.0: 1.0.0 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:32:16.266425+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036225886 tags: - cancer - variant effect prediction title: CHASMplus STAD type: annotator versions: - 1.0.0 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_STAD_mski: code_size: 31094 commercial_warning: null data_size: 131103 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:56:42.154397+0000 requires: - chasmplus_mski_group - chasmplus_STAD size: 162197 tags: - cancer - variant effect prediction title: CHASMplus STAD MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_TGCT: code_size: 31957 commercial_warning: null data_size: 8037056966 data_sources: 1.0.0: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.10: 1.0.0 1.0.11: 1.0.0 1.1.1: 1.0.0 1.1.2: 1.0.0 1.1.3: 1.0.0 1.1.4: 1.0.0 1.2.0: 1.0.0 1.3.0: 1.0.0 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:32:33.420940+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037088923 tags: - cancer - variant effect prediction title: CHASMplus TGCT type: annotator versions: - 1.0.0 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_TGCT_mski: code_size: 33107 commercial_warning: null data_size: 70726 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:57:32.223494+0000 requires: - chasmplus_mski_group - chasmplus_TGCT size: 103833 tags: - cancer - variant effect prediction title: CHASMplus TGCT MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_THCA: code_size: 28076 commercial_warning: null data_size: 8036843336 data_sources: 1.0.0: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.10: 1.0.0 1.0.11: 1.0.0 1.1.1: 1.0.0 1.1.2: 1.0.0 1.1.3: 1.0.0 1.2.0: 1.0.0 1.3.0: 1.0.0 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: Tokheim, C., Karchin, R. (2018). CHASMplus reveals the scope of somatic missense mutations driving human cancers. bioRxiv, 313296. email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:32:50.659466+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036871412 tags: - cancer - variant effect prediction title: CHASMplus THCA type: annotator versions: - 1.0.0 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.2.0 - 1.3.0 chasmplus_THCA_mski: code_size: 31505 commercial_warning: null data_size: 0 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: null 1.2.0: null 1.3.0: null datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:57:32.310134+0000 requires: - chasmplus_mski_group - chasmplus_THCA size: 31505 tags: - cancer - variant effect prediction title: CHASMplus THCA MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_THYM: code_size: 31799 commercial_warning: null data_size: 8037518076 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:33:07.928708+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037549875 tags: - cancer - variant effect prediction title: CHASMplus THYM type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_THYM_mski: code_size: 32929 commercial_warning: null data_size: 62613 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:57:32.394968+0000 requires: - chasmplus_mski_group - chasmplus_THYM size: 95542 tags: - cancer - variant effect prediction title: CHASMplus THYM MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_UCEC: code_size: 31305 commercial_warning: null data_size: 8036360279 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:33:25.575306+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8036391584 tags: - cancer - variant effect prediction title: CHASMplus UCEC type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_UCEC_mski: code_size: 32450 commercial_warning: null data_size: 210309 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:57:32.479160+0000 requires: - chasmplus_mski_group - chasmplus_UCEC size: 242759 tags: - cancer - variant effect prediction title: CHASMplus UCEC MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_UCS: code_size: 30976 commercial_warning: null data_size: 8037627059 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:33:42.780251+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037658035 tags: - cancer - variant effect prediction title: CHASMplus UCS type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_UCS_mski: code_size: 32128 commercial_warning: null data_size: 160616 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:57:32.563008+0000 requires: - chasmplus_mski_group - chasmplus_UCS size: 192744 tags: - cancer - variant effect prediction title: CHASMplus UCS MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_UVM: code_size: 29988 commercial_warning: null data_size: 8037366925 data_sources: 1.0.0: null 1.0.1: null 1.0.10: v1.0.0 1.0.11: v1.0.0 1.1.1: v1.0.0 1.1.2: v1.0.0 1.1.3: v1.0.0 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.1 1.0.10: 1.0.1 1.0.11: 1.0.1 1.1.1: 1.0.1 1.1.2: 1.0.1 1.1.3: 1.0.1 1.1.4: 1.0.1 1.2.0: 1.0.1 1.3.0: 1.0.1 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2019-05-31T03:34:00.072936+0000 requires: - wgndexchasmplussummary - wgchasmplus - chasmplus_group size: 8037396913 tags: - cancer - variant effect prediction title: CHASMplus UVM type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.10 - 1.0.11 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_UVM_mski: code_size: 31139 commercial_warning: null data_size: 100778 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:57:32.673850+0000 requires: - chasmplus_mski_group - chasmplus_UVM size: 131917 tags: - cancer - variant effect prediction title: CHASMplus UVM MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_group: code_size: 76966 commercial_warning: null data_size: 0 data_sources: 1.0.10: v1.0.0 1.2.0: v1.0.0 data_versions: 1.0.10: null 1.2.0: null datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: Tokheim, C., Karchin, R. (2018). CHASMplus reveals the scope of somatic missense mutations driving human cancers. bioRxiv, 313296. email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: [] has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T22:57:32.696802+0000 requires: null size: 76966 tags: - cancer - variant effect prediction title: CHASMplus type: group versions: - 1.0.10 - 1.2.0 chasmplus_mski: code_size: 102524 commercial_warning: null data_size: 175545 data_sources: 1.1.4: v1.0.0 1.2.0: v1.0.0 1.3.0: v1.0.0 data_versions: 1.1.4: 1.1.4 1.2.0: 1.1.4 1.3.0: 1.1.4 datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: - chasmplus_mski_group has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-09-12T22:57:32.743160+0000 requires: - chasmplus_mski_group - chasmplus size: 278069 tags: - cancer - variant effect prediction title: CHASMplus MSK-IMPACT type: annotator versions: - 1.1.4 - 1.2.0 - 1.3.0 chasmplus_mski_group: code_size: 77116 commercial_warning: Freely available for non-commercial use. data_size: 0 data_sources: 1.0.10: v1.0.0 1.2.0: v1.0.0 data_versions: 1.0.10: null 1.2.0: null datasource: v1.0.0 description: CHASMplus is a machine learning algorithm that discriminates somatic missense mutations as either cancer drivers or passengers. Predictions can be done in either a cancer type-specific manner or by a model considering multiple cancer types together (a useful default). Along with scoring each mutation, CHASMplus has a rigorous statistical model to evaluate the statistical significance of predictions. This OpenCRAVAT module represents the v1.0 precompute of CHASMplus (source code v1.0). developer: citation: 'Tokheim C, Karchin R. CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. Cell Syst. 2019. doi: 10.1016/j.cels.2019.05.005. PubMed PMID: 31202631.' email: ctokhei1@alumni.jh.edu name: Collin Tokheim organization: Johns Hopkins University - Karchin Lab website: http://chasmplus.readthedocs.io/en/latest/ groups: [] has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T22:57:32.764237+0000 requires: null size: 77116 tags: - cancer - variant effect prediction title: CHASMplus MSK-IMPACT type: group versions: - 1.0.10 - 1.2.0 civic: code_size: 101689 commercial_warning: null data_size: 143360 data_sources: 0.0.1: null 1.0.1: null 1.0.10: Jan 2019 1.0.11: Jan 2019 1.0.12: Jan 2019 1.0.13: Jan 2019 1.0.14: Jan 2019 1.0.15: Jan 2019 1.0.16: Jan 2019 1.0.17: Latest Available 1.0.18: Latest Available 1.0.2: null 1.0.3: null 1.0.4: Jan 2019 1.0.5: Jan 2019 1.0.7: Jan 2019 1.0.8: Jan 2019 1.0.9: Jan 2019 2023.04.01: 2023.04.01 2023.06.01: 2023.06.01 2023.07.01: 2023.07.01 2023.08.01: 2023.08.01 2023.09.01: 2023.09.01 2023.10.01: 2023.10.01 2023.12.01: 2023.12.01 2024.01.01: 2024.01.01 2024.02.01: 2024.02.01 2024.03.01: 2024.03.01 2024.04.01: 2024.04.01 2024.06.01: 2024.06.01 2024.07.01: 2024.07.01 2024.08.01: 2024.08.01 2024.09.01: 2024.09.01 2024.10.01: 2024.10.01 2024.12.01: 2024.12.01 2025.02.01: 2025.02.01 2025.03.01: 2025.03.01 2025.04.01: 2025.04.01 2025.05.01: 2025.05.01 2025.06.01: 2025.06.01 2025.07.01: 2025.07.01 data_versions: 0.0.1: null 1.0.1: null 1.0.10: null 1.0.11: null 1.0.12: null 1.0.13: null 1.0.14: null 1.0.15: null 1.0.16: null 1.0.17: null 1.0.18: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.0.7: null 1.0.8: null 1.0.9: null 2023.04.01: 2023.04.01 2023.06.01: 2023.06.01 2023.07.01: 2023.07.01 2023.08.01: 2023.08.01 2023.09.01: 2023.09.01 2023.10.01: 2023.10.01 2023.12.01: 2023.12.01 2024.01.01: 2024.01.01 2024.02.01: 2024.02.01 2024.03.01: 2024.03.01 2024.04.01: 2024.04.01 2024.06.01: 2024.06.01 2024.07.01: 2024.07.01 2024.08.01: 2024.08.01 2024.09.01: 2024.09.01 2024.10.01: 2024.10.01 2024.12.01: 2024.12.01 2025.02.01: 2025.02.01 2025.03.01: 2025.03.01 2025.04.01: 2025.04.01 2025.05.01: 2025.05.01 2025.06.01: 2025.06.01 2025.07.01: 2025.07.01 datasource: 2025.07.01 description: Provides descriptions and linkouts to CIViC developer: citation: Griffith, M., Spies, N.C., Krysiak, K., et al. (2017). CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer. Nature Genetics, 49(2):170-174. email: support@opencravat.org name: The McDonnell Genome Institute at Washington University School of Medicine organization: The McDonnell Genome Institute at Washington University School of Medicine website: https://civicdb.org groups: [] has_logo: true hidden: false latest_version: 2025.07.01 publish_time: 2025-07-08T15:12:00.365898+0000 requires: - wgcivic size: 245049 tags: - variants - clinical relevance - cancer - literature title: CIViC type: annotator versions: - 0.0.1 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.0.5 - 1.0.7 - 1.0.8 - 1.0.9 - 1.0.10 - 1.0.11 - 1.0.12 - 1.0.13 - 1.0.14 - 1.0.15 - 1.0.16 - 1.0.17 - 1.0.18 - 2023.04.01 - 2023.06.01 - 2023.07.01 - 2023.08.01 - 2023.09.01 - 2023.10.01 - 2023.12.01 - 2024.01.01 - 2024.02.01 - 2024.03.01 - 2024.04.01 - 2024.06.01 - 2024.07.01 - 2024.08.01 - 2024.09.01 - 2024.10.01 - 2024.12.01 - 2025.02.01 - 2025.03.01 - 2025.04.01 - 2025.05.01 - 2025.06.01 - 2025.07.01 civic_gene: code_size: 330750 commercial_warning: null data_size: 118784 data_sources: 0.0.1: null 0.0.2: null 0.0.3: null 0.0.4: Jan 2019 0.0.5: Jan 2019 1.0.10: Jan 2019 1.0.6: Jan 2019 1.0.7: Jan 2019 1.0.8: Jan 2019 1.0.9: Jan 2019 2023.04.01: 2023.04.01 2023.06.01: 2023.06.01 2023.07.01: 2023.07.01 2023.08.01: 2023.08.01 2023.09.01: 2023.09.01 2023.10.01: 2023.10.01 2023.12.01: 2023.12.01 2024.01.01: 2024.01.01 2024.02.01: 2024.02.01 2024.03.01: 2024.03.01 2024.04.01: 2024.04.01 2024.06.01: 2024.06.01 2024.07.01: 2024.07.01 2024.07.02: 2024.07.02 2024.08.01: 2024.08.01 2024.09.01: 2024.09.01 2024.10.01: 2024.10.01 2024.12.01: 2024.12.01 2025.02.01: 2025.02.01 2025.04.01: 2025.04.01 2025.05.01: 2025.05.01 2025.06.01: 2025.06.01 2025.07.01: 2025.07.01 data_versions: 0.0.1: null 0.0.2: null 0.0.3: null 0.0.4: null 0.0.5: null 1.0.10: null 1.0.6: null 1.0.7: null 1.0.8: null 1.0.9: null 2023.04.01: 2023.04.01 2023.06.01: 2023.06.01 2023.07.01: 2023.07.01 2023.08.01: 2023.08.01 2023.09.01: 2023.09.01 2023.10.01: 2023.10.01 2023.12.01: 2023.12.01 2024.01.01: 2024.01.01 2024.02.01: 2024.02.01 2024.03.01: 2024.03.01 2024.04.01: 2024.04.01 2024.06.01: 2024.06.01 2024.07.01: 2024.07.01 2024.07.02: 2024.07.02 2024.08.01: 2024.08.01 2024.09.01: 2024.09.01 2024.10.01: 2024.10.01 2024.12.01: 2024.12.01 2025.02.01: 2025.02.01 2025.04.01: 2025.04.01 2025.05.01: 2025.05.01 2025.06.01: 2025.06.01 2025.07.01: 2025.07.01 datasource: 2025.07.01 description: Provides descriptions and linkouts to CIViC developer: citation: Griffith, M., Spies, N.C., Krysiak, K., et al. (2017). CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer. Nature Genetics, 49(2):170-174. email: support@opencravat.org name: The McDonnell Genome Institute at Washington University School of Medicine organization: The McDonnell Genome Institute at Washington University School of Medicine website: https://civicdb.org groups: [] has_logo: true hidden: false latest_version: 2025.07.01 publish_time: 2025-07-08T15:12:00.452952+0000 requires: - wgcivic_gene size: 449534 tags: - cancer - clinical relevance - genes - literature title: CIViC Gene type: annotator versions: - 0.0.1 - 0.0.2 - 0.0.3 - 0.0.4 - 0.0.5 - 1.0.6 - 1.0.7 - 1.0.8 - 1.0.9 - 1.0.10 - 2023.04.01 - 2023.06.01 - 2023.07.01 - 2023.08.01 - 2023.09.01 - 2023.10.01 - 2023.12.01 - 2024.01.01 - 2024.02.01 - 2024.03.01 - 2024.04.01 - 2024.06.01 - 2024.07.01 - 2024.07.02 - 2024.08.01 - 2024.09.01 - 2024.10.01 - 2024.12.01 - 2025.02.01 - 2025.04.01 - 2025.05.01 - 2025.06.01 - 2025.07.01 clingen: code_size: 29618 commercial_warning: null data_size: 669964 data_sources: 1.0.0: null 1.0.1: null 1.1.0: null data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.1.0: 1.1.0 datasource: null description: ClinGen is a National Institutes of Health (NIH)-funded resource dedicated to building a central resource that defines the clinical relevance of genes and variants for use in precision medicine and research. developer: citation: 'Strande NT, Riggs ER, Buchanan AH, Ceyhan-Birsoy O, DiStefano M, Dwight SS, Goldstein J, Ghosh R, Seifert BA, Sneddon TP, Wright MW, Milko LV, Cherry JM, Giovanni MA, Murray MF, O''Daniel JM, Ramos EM, Santani AB, Scott AF, Plon SE, Rehm HL, Martin CL, Berg JS. Evaluating the Clinical Validity of Gene-Disease Associations: An Evidence-Based Framework Developed by the Clinical Genome Resource. Am J Hum Genet. 2017 Jun 1;100(6):895-906. doi: 10.1016/j.ajhg.2017.04.015. Epub 2017 May 25. PubMed PMID: 28552198; PubMed Central PMCID: PMC5473734.' email: clingen@clinicalgenome.org name: Katrina Goddard organization: National Institutes of Health website: https://clinicalgenome.org groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2020-08-21T18:36:56.505747+0000 requires: - wgclingen size: 699582 tags: - genes - clinical relevance title: ClinGen Gene type: annotator versions: - 1.0.0 - 1.0.1 - 1.1.0 clingen-converter: code_size: 14421 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null data_versions: 1.0.0: null 1.0.1: null datasource: null description: File converter for Clingen Allele Registry Canonical Allele Identifiers developer: citation: '' email: kanderson@potomacitgroup.com name: Kyle Anderson organization: Potomac IT Group website: https://potomacitgroup.com/ groups: [] has_logo: true hidden: false latest_version: 1.0.1 publish_time: 2024-10-28T20:02:18.158906+0000 requires: null size: 14421 tags: - input/output title: Clingen Allele Registry Converter type: converter versions: - 1.0.0 - 1.0.1 clingen_allele_registry: code_size: 224959 commercial_warning: null data_size: 6942720 data_sources: 1.0.0: Latest Available 1.1.0: ClinGen Allele Registry API 1.1.1: ClinGen Allele Registry API data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 1.1.1: 1.0.0 datasource: ClinGen Allele Registry API description: Provide Clingen Allele Registry Identifiers for variants. developer: citation: Pawliczek P, Patel RY, Ashmore LR, Jackson AR, Bizon C, Nelson T, Powell B, Freimuth RR, Strande N, Shah N, Paithankar S, Wright MW, Dwight S, Zhen J, Landrum M, McGarvey P, Babb L, Plon SE, Milosavljevic A, Clinical Genome (ClinGen) Resource. ClinGen Allele Registry links information about genetic variants. Hum Mutat. 2018 Nov,39(11) 1690-1701. doi 10.1002/humu.23637. PMID 30311374, PMCID PMC6519371. email: support@opencravat.org name: ClinGen - Clinical Genome Resource organization: ClinGen - Clinical Genome Resource website: https://clinicalgenome.org/ groups: [] has_logo: true hidden: false latest_version: 1.1.1 publish_time: 2025-02-18T18:52:06.417728+0000 requires: null size: 7167679 tags: - clinical relevance - variants title: ClinGen Allele Registry type: annotator versions: - 1.0.0 - 1.1.0 - 1.1.1 clinpred: code_size: 135695 commercial_warning: null data_size: 3788716036 data_sources: 1.0.0: October 2018 data_versions: 1.0.0: 1.0.0 datasource: October 2018 description: Prediction tool to identify disease-relevant nonsynonymous single nucleotide variants. developer: citation: "Alirezaie N, Kernohan KD, Hartley T, Majewski J, Hocking TD. \u201C\ ClinPred: Prediction Tool to Identify Disease-Relevant Nonsynonymous Single-Nucleotide\ \ Variants.\u201D American Journal of Human 2018 Oct 4;103(4):474-483. PMID:30220433" email: support@cravat.us name: Najmeh Alirezaie and Jacek Majewski organization: McGill University website: https://sites.google.com/site/clinpred/home groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2021-03-03T18:47:32.430896+0000 requires: null size: 3788851731 tags: - variants - variant effect prediction - clinical relevance title: ClinPred type: annotator versions: - 1.0.0 clinvar: code_size: 325217 commercial_warning: null data_size: 1437616132 data_sources: 2018.04.06: 2018.04.06 2018.04.061: 2018.04.06 2018.04.062: 2018.04.06 2019.01.021: 2019.01.02 2019.01.022: 2019.01.02 2019.01.024: 2019.01.02 2019.01.025: 2019.01.02 2019.02.006: 2019.01.02 2019.03.20: 2019.01.02 2019.03.26: 2019.01.02 2019.03.261: 2019.01.02 2019.05.13: 2019.01.02 2019.08.02: 2019.01.02 2019.08.23: 2019.01.02 2020.02.11: 2020.02.11 2020.02.11.1: 2020.02.11 2020.11.02: 2020.02.11 2021.01.12: 2021.01.11 2021.02.04: 2021.02.04 2021.03.03: 2021.03.03 2021.04.01: 2021.04.01 2021.05.01: 2021.05.01 2021.06.01: 2021.06.01 2021.08.01: 2021.08.01 2021.09.01: 2021.09.01 2021.10.01: 2021.10.01 2022.03.06: 2022.03.06 2022.06.14: 2022.06.14 2022.11.14: 2023.01.01 2023.02.01: 2023.02.01.1 2024.02.01: 2024.02.01 2024.03.01: 2024.03.01 2024.04.01: 2024.04.01 2024.05.01: 2024.05.01 2024.08.01: 2024.08.01 2024.08.09: 2024.08.09 2024.09.01: 2024.09.01 2024.10.01: 2024.10.01 2024.12.01: 2024.12.01 2025.02.01: 2025.02.01 2025.03.01: 2025.03.01 2025.04.01: 2025.04.01 2025.05.01: 2025.05.01 2025.06.01: 2025.06.01 2025.07.01: 2025.07.01 data_versions: 2018.04.06: 2018.04.06 2018.04.061: 2018.04.061 2018.04.062: 2018.04.061 2019.01.021: 2018.04.061 2019.01.022: 2019.01.022 2019.01.024: 2019.01.022 2019.01.025: 2019.01.022 2019.02.006: 2019.01.022 2019.03.20: 2019.01.022 2019.03.26: 2019.01.022 2019.03.261: 2019.01.022 2019.05.13: 2019.01.022 2019.08.02: 2019.01.022 2019.08.23: 2019.01.022 2020.02.11: 2020.02.11 2020.02.11.1: 2020.02.11 2020.11.02: 2020.11.02 2021.01.12: 2021.01.12 2021.02.04: 2021.02.04 2021.03.03: 2021.03.03 2021.04.01: 2021.04.01 2021.05.01: 2021.05.01 2021.06.01: 2021.06.01 2021.08.01: 2021.08.01 2021.09.01: 2021.09.01 2021.10.01: 2021.10.01 2022.03.06: 2022.03.06 2022.06.14: 2022.06.14 2022.11.14: 2022.11.14 2023.02.01: 2023.02.01 2024.02.01: 2024.02.01 2024.03.01: 2024.03.01 2024.04.01: 2024.04.01 2024.05.01: 2024.05.01 2024.08.01: 2024.08.01 2024.08.09: 2024.08.01 2024.09.01: 2024.09.01 2024.10.01: 2024.10.01 2024.12.01: 2024.12.01 2025.02.01: 2025.02.01 2025.03.01: 2025.03.01 2025.04.01: 2025.04.01 2025.05.01: 2025.05.01 2025.06.01: 2025.06.01 2025.07.01: 2025.07.01 datasource: 2025.07.01 description: ClinVar is an archive of reports of the relationships among human variations and phenotypes, with supporting evidence. developer: citation: 'Landrum, M.J., Lee, J.M., Benson, M., et al. (2016). ClinVar: public archive of interpretations of clinically relevant variants. Nucleic Acids Research, 44(D1):D862-8.' email: support@opencravat.org name: NCBI organization: NCBI website: https://www.ncbi.nlm.nih.gov/clinvar/ groups: [] has_logo: true hidden: false latest_version: 2025.07.01 publish_time: 2025-07-08T15:12:47.807177+0000 requires: - wgclinvar size: 1437941349 tags: - clinical relevance - variants title: ClinVar type: annotator versions: - 2018.04.06 - 2018.04.061 - 2018.04.062 - 2019.01.021 - 2019.01.022 - 2019.01.024 - 2019.01.025 - 2019.02.006 - 2019.03.20 - 2019.03.26 - 2019.03.261 - 2019.05.13 - 2019.08.02 - 2019.08.23 - 2020.02.11 - 2020.02.11.1 - 2020.11.02 - 2021.01.12 - 2021.02.04 - 2021.03.03 - 2021.04.01 - 2021.05.01 - 2021.06.01 - 2021.08.01 - 2021.09.01 - 2021.10.01 - 2022.03.06 - 2022.06.14 - 2022.11.14 - 2023.02.01 - 2024.02.01 - 2024.03.01 - 2024.04.01 - 2024.05.01 - 2024.08.01 - 2024.08.09 - 2024.09.01 - 2024.10.01 - 2024.12.01 - 2025.02.01 - 2025.03.01 - 2025.04.01 - 2025.05.01 - 2025.06.01 - 2025.07.01 clinvar_acmg: code_size: 97401 commercial_warning: null data_size: 119287808 data_sources: 2020.10.05: 2020.10.05 2021.01.13: 2021.01.13 2021.02.04: 2021.02.04 2021.03.03: 2021.03.03 2021.04.01: 2021.04.01 2021.05.01: 2021.05.01 2021.06.01: 2021.06.01 2021.08.01: 2021.08.01 2021.09.01: 2021.09.01 2021.10.01: 2021.10.01 2022.11.01: 2022.11.01 2022.12.01: 2022.12.01 2023.01.01: 2023.01.01 2023.02.01: 2023.02.01 2024.02.01: 2024.02.01 2024.03.01: 2024.03.01 2024.04.01: 2024.04.01 2024.05.01: 2024.05.01 2024.08.01: 2024.08.01 2024.09.01: 2024.09.01 2025.02.01: 2025.02.01 2025.03.01: 2025.03.01 2025.04.01: 2025.04.01 2025.05.01: 2025.05.01 data_versions: 2020.10.05: 2020.10.05 2021.01.13: 2021.01.13 2021.02.04: 2021.02.04 2021.03.03: 2021.03.03 2021.04.01: 2021.04.01 2021.05.01: 2021.05.01 2021.06.01: 2021.06.01 2021.08.01: 2021.08.01 2021.09.01: 2021.09.01 2021.10.01: 2021.10.01 2022.11.01: 2022.11.01 2022.12.01: 2022.12.01 2023.01.01: 2023.01.01 2023.02.01: 2023.02.01 2024.02.01: 2024.02.01 2024.03.01: 2024.03.01 2024.04.01: 2024.04.01 2024.05.01: 2024.05.01 2024.08.01: 2024.08.01 2024.09.01: 2024.09.01 2025.02.01: 2025.02.01 2025.03.01: 2025.03.01 2025.04.01: 2025.04.01 2025.05.01: 2025.05.01 datasource: 2025.05.01 description: ACMG PS1 and PM5 pathogenicity prediction based on ClinVar developer: citation: 'Landrum, M.J., Lee, J.M., Benson, M., et al. (2016). ClinVar: public archive of interpretations of clinically relevant variants. Nucleic Acids Research, 44(D1):D862-8.' email: support@opencravat.org name: NCBI organization: NCBI website: https://www.ncbi.nlm.nih.gov/clinvar/ groups: [] has_logo: true hidden: false latest_version: 2025.05.01 publish_time: 2025-05-05T17:17:07.031874+0000 requires: null size: 119385209 tags: - clinical relevance - variants title: ClinVar ACMG type: annotator versions: - 2020.10.05 - 2021.01.13 - 2021.02.04 - 2021.03.03 - 2021.04.01 - 2021.05.01 - 2021.06.01 - 2021.08.01 - 2021.09.01 - 2021.10.01 - 2022.11.01 - 2022.12.01 - 2023.01.01 - 2023.02.01 - 2024.02.01 - 2024.03.01 - 2024.04.01 - 2024.05.01 - 2024.08.01 - 2024.09.01 - 2025.02.01 - 2025.03.01 - 2025.04.01 - 2025.05.01 cohortcompare: code_size: 30367 commercial_warning: null data_size: 0 data_sources: 1.2.0: null data_versions: 1.2.0: null datasource: null description: Performs case-control analysis on cohorts developer: citation: '' email: support@opencravat.org name: Kyle Moad organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2024-12-17T20:47:30.836071+0000 requires: - wgcasecontrolsummary - wgcasecontrols size: 30367 tags: null title: Cohort Compare type: postaggregator versions: - 1.2.0 cosmic: code_size: 2651740 commercial_warning: For commercial use, contact cosmic@sanger.ac.uk data_size: 1728538628 data_sources: 100.0.0: v100 85.0.0: v85 85.0.1: v85 85.0.11: v85 85.0.12: v85 85.0.13: v85 85.0.14: v85 85.0.15: v85 85.0.2: v85 85.0.3: v85 85.0.4: v85 85.0.5: v85 85.0.6: v85 85.0.7: v85 85.0.8: v85 85.0.9: v85 91.0.0: v91 91.0.1: v91 92.0.0: v92 92.1.0: v92 94.0.0: v94 99.0.0: v99 data_versions: 100.0.0: 100.0.0 85.0.0: 85.0.0 85.0.1: 85.0.0 85.0.11: 85.0.0 85.0.12: 85.0.0 85.0.13: 85.0.0 85.0.14: 85.0.0 85.0.15: 85.0.0 85.0.2: 85.0.0 85.0.3: 85.0.0 85.0.4: 85.0.0 85.0.5: 85.0.0 85.0.6: 85.0.0 85.0.7: 85.0.0 85.0.8: 85.0.0 85.0.9: 85.0.0 91.0.0: 91.0.0 91.0.1: 91.0.0 92.0.0: 92.0.0 92.1.0: 92.1.0 94.0.0: 94.0.0 99.0.0: 99.0.0 datasource: v100 description: Catalogue Of Somatic Mutations In Cancer, is the world's largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer. developer: citation: 'Forbes, S.A., Beare, D., Boutselakis, H., et al. (2017). COSMIC: somatic cancer genetics at high-resolution. Nucleic Acids Research, 45(D1):D777-D783.' email: support@opencravat.org name: Sanger Institute organization: Sanger Institute website: https://cancer.sanger.ac.uk/cosmic groups: [] has_logo: true hidden: false latest_version: 100.0.0 publish_time: 2024-12-17T20:11:42.914330+0000 requires: - wgcosmic size: 1731190368 tags: - cancer - genes - variants title: COSMIC type: annotator versions: - 85.0.0 - 85.0.1 - 85.0.2 - 85.0.3 - 85.0.4 - 85.0.5 - 85.0.6 - 85.0.7 - 85.0.8 - 85.0.9 - 85.0.11 - 85.0.12 - 85.0.13 - 85.0.14 - 85.0.15 - 91.0.0 - 91.0.1 - 92.0.0 - 92.1.0 - 94.0.0 - 99.0.0 - 100.0.0 cosmic_gene: code_size: 2712669 commercial_warning: 'For commercial use, contact cosmic@sanger.ac.uk ' data_size: 136951812 data_sources: 100.0.0: v100 85.0.0: v85 85.0.1: v85 85.0.2: v85 85.0.3: v85 85.0.4: v85 85.0.5: v85 85.0.6: v85 91.0.0: v91 91.0.1: v91 92.0.0: v92 94.0.0: v94 99.0.0: v99 data_versions: 100.0.0: 100.0.0 85.0.0: 85.0.0 85.0.1: 85.0.0 85.0.2: 85.0.2 85.0.3: 85.0.3 85.0.4: 85.0.3 85.0.5: 85.0.3 85.0.6: 85.0.3 91.0.0: 91.0.0 91.0.1: 91.0.0 92.0.0: 92.0.0 94.0.0: 94.0.0 99.0.0: 99.0.0 datasource: v100 description: Catalogue Of Somatic Mutations In Cancer, is the world's largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer. developer: citation: "Simon A. Forbes et al; COSMIC: somatic cancer genetics at high-resolution,\ \ Nucleic Acids Research, Volume 45, Issue D1, 4 January 2017, Pages D777\u2013\ D783, https://doi.org/10.1093/nar/gkw1121" email: support@opencravat.org name: Sanger Institute organization: Sanger Institute website: https://cancer.sanger.ac.uk/cosmic groups: [] has_logo: true hidden: false latest_version: 100.0.0 publish_time: 2024-12-17T20:13:35.682059+0000 requires: - wgcosmic_gene size: 139664481 tags: - genes - cancer title: COSMIC Gene type: annotator versions: - 85.0.0 - 85.0.1 - 85.0.2 - 85.0.3 - 85.0.4 - 85.0.5 - 85.0.6 - 91.0.0 - 91.0.1 - 92.0.0 - 94.0.0 - 99.0.0 - 100.0.0 cravat-converter: code_size: 11136 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.1.0: null 1.1.1: null 1.1.2: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.1.0: null 1.1.1: null 1.1.2: null datasource: null description: File converter for standard cravat input developer: citation: '' email: kmoad@insilico.us.com name: Kyle Moad organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.1.2 publish_time: '2018-12-10T16:51:10.000000' requires: null size: 11136 tags: null title: Cravat Converter type: converter versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.0.5 - 1.1.0 - 1.1.1 - 1.1.2 cscape: code_size: 50444 commercial_warning: null data_size: 59852766222 data_sources: 1.0.0: 2017 1.0.1: 2017 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 datasource: 2017 description: CScape predicts the oncogenic status (disease-driver or neutral) of somatic point mutations in coding and non coding region of the cancer genome. developer: citation: 'Rogers MF, Shihab H, Gaunt TR, Campbell C (2017). CScape: a tool for predicting oncogenic single-point mutations in the cancer genome. Nature Scientific Reports' email: suppor@cravat.us name: '' organization: University of Bristol Integrative Epidemiology Unit website: http://cscape.biocompute.org.uk/ groups: [] has_logo: true hidden: false latest_version: 1.0.1 publish_time: 2021-04-27T15:41:23.202196+0000 requires: null size: 59852816666 tags: - cancer - non coding - variant effect prediction - variants title: CScape type: annotator versions: - 1.0.0 - 1.0.1 cscape_coding: code_size: 190560 commercial_warning: null data_size: 5212235780 data_sources: 1.0.0: 2017 data_versions: 1.0.0: 1.0.0 datasource: 2017 description: CScape predicts the oncogenic status (disease-driver or neutral) of somatic point mutations in the coding region of the cancer genome. developer: citation: 'Rogers MF, Shihab H, Gaunt TR, Campbell C (2017). CScape: a tool for predicting oncogenic single-point mutations in the cancer genome. Nature Scientific Reports' email: suppor@cravat.us name: '' organization: University of Bristol Integrative Epidemiology Unit website: http://cscape.biocompute.org.uk/ groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2023-06-22T17:51:15.415186+0000 requires: null size: 5212426340 tags: - cancer - variant effect prediction - variants title: CScape Coding type: annotator versions: - 1.0.0 csvreporter: code_size: 265067 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.4: null 1.0.7: null 1.0.8: null 1.0.9: null 2.0.0: null 2.0.2: null 2.0.3: null 2.0.4: null 2.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.4: null 1.0.7: null 1.0.8: null 1.0.9: null 2.0.0: null 2.0.2: null 2.0.3: null 2.0.4: null 2.1.0: null datasource: null description: CSV format text file reporter developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: false latest_version: 2.1.0 publish_time: 2019-06-12T17:11:21.008048+0000 requires: null size: 265067 tags: - input/output title: CSV Reporter type: reporter versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.4 - 1.0.7 - 1.0.8 - 1.0.9 - 2.0.0 - 2.0.2 - 2.0.3 - 2.0.4 - 2.1.0 dann: code_size: 537094 commercial_warning: null data_size: 109595992123 data_sources: 1.0.0: March 2015 1.0.1: March 2015 1.0.2: March 2015 1.1.0: March 2015 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.0.2: 1.0.0 1.1.0: 1.0.0 datasource: March 2015 description: A deep learning approach for annotating the pathogenicity of genetic variants. developer: citation: 'Quang, Daniel, Yifei Chen, and Xiaohui Xie. "DANN: a deep learning approach for annotating the pathogenicity of genetic variants." Bioinformatics 31.5 (2015): 761-763.' email: support@opencravat.org name: Center for Complex Biological Systems, University of California organization: Center for Complex Biological Systems, University of California website: https://sites.google.com/site/jpopgen/dbNSFP groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2021-06-09T22:28:46.996583+0000 requires: null size: 109596529217 tags: - non coding - variant effect prediction - variants title: DANN type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 dann_coding: code_size: 125388 commercial_warning: Freely available for non-commercial use. data_size: 4316903428 data_sources: 1.0.0: v4.1 1.1.0: v4.1 data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: v4.1 description: DANN is a functional prediction score retrained based on the training data of CADD using deep neural network. developer: citation: 'Quang, Daniel, Yifei Chen, and Xiaohui Xie. "DANN: a deep learning approach for annotating the pathogenicity of genetic variants." Bioinformatics 31.5 (2015): 761-763.' email: support@opencravat.org name: Center for Complex Biological Systems, University of California organization: Center for Complex Biological Systems, University of California website: https://sites.google.com/site/jpopgen/dbNSFP groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2024-12-17T20:15:28.091922+0000 requires: null size: 4317028816 tags: - variant effect prediction - variants title: DANN Coding type: annotator versions: - 1.0.0 - 1.1.0 dbcid: code_size: 163956 commercial_warning: null data_size: 47108 data_sources: 1.0.0: v1.0 1.0.1: v1.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 datasource: v1.0 description: The database of Cancer driver InDels (dbCID) is a highly curated database of driver indels (insertions and deletions) that are likely to engage in cancer development, progression, or therapy. developer: citation: "Yue, Zhenyu et al. \u201CdbCID: a manually curated resource for exploring\ \ the driver indels in human cancer.\u201D Briefings in bioinformatics vol.\ \ 20,5 (2019): 1925-1933. doi:10.1093/bib/bby059" email: support@opencravat.org name: '' organization: AnHui University website: http://bioinfo.ahu.edu.cn:8080/dbCID groups: [] has_logo: true hidden: false latest_version: 1.0.1 publish_time: 2021-04-26T15:01:40.024228+0000 requires: null size: 211064 tags: - cancer - variants title: 'dbCID: Database of Cancer Driver InDels' type: annotator versions: - 1.0.0 - 1.0.1 dbscsnv: code_size: 109418 commercial_warning: null data_size: 754368512 data_sources: 1.0.0: v1.1 1.1.0: v1.1 data_versions: 1.0.0: 1.0.0 1.1.0: 1.1.0 datasource: v1.1 description: A comprehensive database of all potential human SNVs within splicing consensus regions and their functional annotations. developer: citation: 'Jian, Xueqiu, Eric Boerwinkle, and Xiaoming Liu. "In silico prediction of splice-altering single nucleotide variants in the human genome." Nucleic acids research 42.22 (2014): 13534-13544.' email: support@opencravat.org name: Xiaoming Liu organization: University of South Florida website: http://www.liulab.science/dbscsnv.html groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2020-09-15T20:18:47.460936+0000 requires: null size: 754477930 tags: - variant effect prediction - variants title: dbscSNV type: annotator versions: - 1.0.0 - 1.1.0 dbsnp: code_size: 213708 commercial_warning: null data_size: 52769945604 data_sources: 151.0.0: null 151.0.1: null 151.0.2: v151 151.0.3: v151 151.0.4: v151 151.0.5: v151 151.0.6: v151 151.0.7: v151 151.0.8: v151 151.0.9: v151 154.0.0: v154 154.0.1: v154 154.0.2: v154 156.0.0: v156 156.0.1: v156 data_versions: 151.0.0: 151.0.0 151.0.1: 151.0.0 151.0.2: 151.0.0 151.0.3: 151.0.0 151.0.4: 151.0.0 151.0.5: 151.0.0 151.0.6: 151.0.0 151.0.7: 151.0.0 151.0.8: 151.0.0 151.0.9: 151.0.0 154.0.0: 154.0.0 154.0.1: 154.0.1 154.0.2: 154.0.1 156.0.0: 156.0.0 156.0.1: 156.0.1 datasource: v156 description: Comprehensive database of both single base nucleotide subsitutions and short deletion and insertion polymorphisms developer: citation: 'Sherry, S.T., Ward, M., Kholodov, M., Baker, J., Phan, L., Smigielski, E.M., & Sirotkin, K. (2001). dbSNP: the NCBI database of genetic variation. Nucleic acids research, 29 1, 308-11 .' email: support@opencravat.org name: NCBI organization: NCBI website: https://www.ncbi.nlm.nih.gov/projects/SNP/ groups: [] has_logo: true hidden: false latest_version: 156.0.1 publish_time: 2024-05-14T03:08:13.178419+0000 requires: null size: 52770159312 tags: - variants - literature title: dbSNP type: annotator versions: - 151.0.0 - 151.0.1 - 151.0.2 - 151.0.3 - 151.0.4 - 151.0.5 - 151.0.6 - 151.0.7 - 151.0.8 - 151.0.9 - 154.0.0 - 154.0.1 - 154.0.2 - 156.0.0 - 156.0.1 dbsnp-converter: code_size: 12785 commercial_warning: null data_size: 30397822980 data_sources: 1.0.0: null 1.0.1: null 1.0.2: '153' 1.1.0: '153' 1.1.1: '153' 1.2.0: v154 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.0.2: 1.0.2 1.1.0: 1.0.2 1.1.1: 1.0.2 1.2.0: 1.2.0 datasource: v154 description: Input converter for dbSNP rsid input developer: citation: 'Database of Single Nucleotide Polymorphisms (dbSNP). Bethesda (MD): National Center for Biotechnology Information, National Library of Medicine. (dbSNP Build ID: 151).' email: support@opencravat.org name: Kyle Moad organization: In Silico Solutions website: https://www.ncbi.nlm.nih.gov/snp groups: [] has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2024-12-17T20:45:37.471486+0000 requires: null size: 30397835765 tags: - input/output title: dbSNP Converter type: converter versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 - 1.1.1 - 1.2.0 dbsnp_common: code_size: 164939 commercial_warning: null data_size: 1254324228 data_sources: 1.0.1: v154 1.1.0: v156 1.1.1: v156 data_versions: 1.0.1: 1.0.1 1.1.0: 1.1.0 1.1.1: 1.1.1 datasource: v156 description: Selection of SNPs with a minor allele frequency of 1% or greater is an attempt to identify variants that appear to be reasonably common in the general population. developer: citation: 'Sherry ST, Ward MH, Kholodov M, Baker J, Phan L, Smigielski EM, Sirotkin K. dbSNP: the NCBI database of genetic variation. Nucleic Acids Res. 2001 Jan 1;29(1):308-11. PMID: 11125122; PMC: PMC29783' email: supprt@cravat.us name: NCBI organization: NCBI website: https://genome.ucsc.edu/cgi-bin/hgTrackUi?hgsid=784649537_AtjYqLFz0CTNkRh8qWf8vOHQpNXp&c=chr1&g=snp151Common groups: [] has_logo: true hidden: false latest_version: 1.1.1 publish_time: 2024-05-15T10:20:24.011752+0000 requires: null size: 1254489167 tags: - literature - variants title: dbSNP Common type: annotator versions: - 1.0.1 - 1.1.0 - 1.1.1 denovo: code_size: 186498 commercial_warning: null data_size: 38727680 data_sources: 1.6.1: null 1.6.10: v161 1.6.11: v161 1.6.2: null 1.6.3: v161 1.6.4: v161 1.6.5: v161 1.6.7: v161 1.6.8: v161 1.6.9: v161 data_versions: 1.6.1: 1.6.1 1.6.10: 1.6.1 1.6.11: 1.6.1 1.6.2: 1.6.1 1.6.3: 1.6.1 1.6.4: 1.6.1 1.6.5: 1.6.1 1.6.7: 1.6.1 1.6.8: 1.6.1 1.6.9: 1.6.1 datasource: v161 description: Denovo annotation. Denovo is a collection of germline variants in the human genome which are present in children but not their parents. developer: citation: 'Turner, T.N., Yi, Q., Krumm, N., Huddleston, J., Hoekzema, K., Stessman, H.A., Doebley, A., Bernier, R.A., Nickerson, D.A., & Eichler, E.E. (2017). denovo-db: a compendium of human de novo variants. Nucleic Acids Research, 45(D1):D804-D811.' email: support@opencravat.org name: Tychele Turner organization: University of Washington website: http://denovo-db.gs.washington.edu/ groups: [] has_logo: true hidden: false latest_version: 1.6.11 publish_time: 2019-01-30T18:37:48.877593+0000 requires: null size: 38914178 tags: - variants - clinical relevance title: Denovo-DB type: annotator versions: - 1.6.1 - 1.6.2 - 1.6.3 - 1.6.4 - 1.6.5 - 1.6.7 - 1.6.8 - 1.6.9 - 1.6.10 - 1.6.11 dgi: code_size: 265380 commercial_warning: null data_size: 7256068 data_sources: 1.0.0: Jan 2021 data_versions: 1.0.0: 1.0.0 datasource: Jan 2021 description: The goal of DGIdb is to help you annotate your genes of interest with respect to known drug-gene interactions and potential druggability. developer: citation: "Freshour, Sharon L., et al. \"Integration of the Drug\u2013Gene Interaction\ \ Database (DGIdb 4.0) with open crowdsource efforts.\" Nucleic Acids Research\ \ 49.D1 (2021): D1144-D1151." email: support@opencravat.org name: '' organization: Washington University School of Medicine website: https://dgidb.org/ groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-12-17T20:21:06.494564+0000 requires: - wgdgi size: 7521448 tags: - clinical relevance - variants title: 'DGIdb: The Drug Interaction Database' type: annotator versions: - 1.0.0 ditto: code_size: 428796 commercial_warning: null data_size: 178080273672 data_sources: 0.0.1: null 0.0.2: 0.0.1 data_versions: 0.0.1: 0.0.1 0.0.2: 0.0.1 datasource: 0.0.1 description: DITTO is a transcript-aware explainable Machine Learning tool for scoring the pathogenicity of any type of small variants. developer: citation: 'Mamidi, T.K.K.; Wilk, B.M.; Gajapathy, M.; Worthey, E.A. DITTO: An Explainable Machine-Learning Model for Transcript-Specific Variant Pathogenicity Prediction. Preprints 2024, 2024040837. https://doi.org/10.20944/preprints202404.0837.v1' email: tmamidi@uab.edu name: Tarun Mamidi organization: The University of Alabama at Birmingham website: https://github.com/uab-cgds-worthey/DITTO groups: [] has_logo: false hidden: false latest_version: 0.0.2 publish_time: 2024-12-11T01:57:45.115051+0000 requires: - wgditto size: 178080702468 tags: - variant effect prediction - variants title: DITTO type: annotator versions: - 0.0.1 - 0.0.2 drug_interaction: code_size: 991833 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: Package that identifies variants with potential impact on drug responce. developer: citation: '' email: support@opencravat.org name: OpenCRAVAT Team organization: KarchinLab website: https://opencravat.org groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2023-02-27T17:52:56.383021+0000 requires: - clinvar - pharmgkb - clingen - dgi - tsvreporter size: 991833 tags: null title: Drug Interaction Package type: package versions: - 1.0.0 encode_tfbs: code_size: 706464 commercial_warning: null data_size: 577908736 data_sources: 1.0.0: 2012-03 1.0.1: 2012-03 1.0.2: 2012-03 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.0.2: 1.0.0 datasource: 2012-03 description: Human transcription factor binding sites based on ChIP-seq experiments generated by production groups in the ENCODE Consortium. developer: citation: "ENCODE Project Consortium. An integrated encyclopedia of DNA elements\ \ in the human genome. Nature 489, 57\u201374 (2012)." email: '' name: ENCODE Project Consortium organization: ENCODE Project Consortium website: http://genome.ucsc.edu/cgi-bin/hgFileUi?db=hg19&g=wgEncodeAwgTfbsUniform#TRACK_HTML groups: [] has_logo: true hidden: false latest_version: 1.0.2 publish_time: 2020-08-21T18:44:35.954192+0000 requires: - wgencode_tfbs - hg19 size: 578615200 tags: - non coding title: ENCODE TFBS type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.2 ensembl_regulatory_build: code_size: 83449 commercial_warning: null data_size: 49477636 data_sources: 1.0.0: 2020.06.09 1.0.1: 2020.06.09 1.0.2: 2020.06.09 1.0.3: 2020.06.09 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.0.2: 1.0.0 1.0.3: 1.0.0 datasource: 2020.06.09 description: An up-to-date and comprehensive summary of regulatory features across the genome, as well as popular curated external resources. developer: citation: 'Zerbino DR, Wilder SP, Johnson N, Juettemann T, Flicek PR. The ensembl regulatory build. Genome Biology. 2015 Mar;16:56. DOI: 10.1186/s13059-015-0621-5.' email: support@opencravat.org name: Ensembl organization: Ensembl website: https://uswest.ensembl.org/info/genome/funcgen/regulatory_build.html groups: [] has_logo: true hidden: false latest_version: 1.0.3 publish_time: 2020-09-29T15:47:28.142064+0000 requires: - wgensembl_regulatory_build size: 49561085 tags: - non coding title: Ensembl Regulatory Build type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 esm1b: code_size: 16504 commercial_warning: null data_size: 6655320064 data_sources: 1.0.0: dbNSFP v4.7a 1.0.1: dbNSFP v4.7a 1.1.0: dbNSFP v4.7a data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.1.0: 1.0.0 datasource: dbNSFP v4.7a description: ESM1b is a 650-million-parameter protein language model to predict all ~450 million possible missense variant effects in the human genome. developer: citation: "Brandes, N., Goldman, G., Wang, C.H. et al. Genome-wide prediction\ \ of disease variant effects with a deep protein language model. Nat Genet 55,\ \ 1512\u20131522 (2023). https://doi.org/10.1038/s41588-023-01465-0" email: support@opencravat.org name: Ntranos Lab organization: University of California San Francisco website: https://huggingface.co/spaces/ntranoslab/esm_variants groups: [] has_logo: false hidden: false latest_version: 1.1.0 publish_time: 2024-05-09T16:27:58.505774+0000 requires: - wgesm1b size: 6655336568 tags: - variant effect prediction - variants title: ESM1b type: annotator versions: - 1.0.0 - 1.0.1 - 1.1.0 esp6500: code_size: 1454140 commercial_warning: null data_size: 114604032 data_sources: 1.0.0: null 6500.2.0: null 6500.2.1: v.0.0.30 6500.2.2: v.0.0.30 6500.2.3: v0.0.30 6500.2.4: v0.0.30 6500.2.5: v0.0.30 6500.2.6: v0.0.30 data_versions: 1.0.0: 1.0.0 6500.2.0: 1.0.0 6500.2.1: 1.0.0 6500.2.2: 1.0.0 6500.2.3: 1.0.0 6500.2.4: 1.0.0 6500.2.5: 1.0.0 6500.2.6: 1.0.0 datasource: v0.0.30 description: Exome Sequencing Project 6500 developer: citation: Exome Variant Server, NHLBI GO Exome Sequencing Project (ESP), Seattle, WA email: evsserver@uw.edu name: University of Washington organization: University of Washington website: http://evs.gs.washington.edu/EVS/ groups: [] has_logo: true hidden: false latest_version: 6500.2.6 publish_time: 2019-01-30T01:56:13.545867+0000 requires: - wgesp6500 size: 116058172 tags: - allele frequency title: ESP6500 type: annotator versions: - 1.0.0 - 6500.2.0 - 6500.2.1 - 6500.2.2 - 6500.2.3 - 6500.2.4 - 6500.2.5 - 6500.2.6 ess_gene: code_size: 19718 commercial_warning: null data_size: 321540 data_sources: 3.5.0: null 3.5.01: null 3.5.02: dbNSFP v4.0b1 3.5.03: dbNSFP v4.0b1 3.5.04: dbNSFP v4.0b1 3.5.5: dbNSFP v4.0b1 3.5.6: dbNSFP v4.0b1 3.5.7: dbNSFP v4.0b1 3.5.8: dbNSFP v4.0b1 data_versions: 3.5.0: 3.5.0 3.5.01: 3.5.0 3.5.02: 3.5.0 3.5.03: 3.5.0 3.5.04: 3.5.04 3.5.5: 3.5.04 3.5.6: 3.5.04 3.5.7: 3.5.04 3.5.8: 3.5.04 datasource: dbNSFP v4.0b1 description: Essential Genes provides a database of genetic variation & mutational burden in 2472 human orthologs developer: citation: 'Georgi, B., Voight, B.F., & Bucan, M. (2013). From Mouse to Human: Evolutionary Genomics Analysis of Human Orthologs of Essential Genes. PLoS genetics 9(5): e1003484.' email: support@opencravat.org name: "Benjamin Georgi, Benjamin F. Voight, Maja Bu\u0107an" organization: Department of Genetics, University of Pennsylvania website: https://doi.org/10.1371/journal.pgen.1003484 groups: [] has_logo: true hidden: false latest_version: 3.5.8 publish_time: 2019-01-30T18:39:07.249427+0000 requires: null size: 341258 tags: - genes title: Essential Genes type: annotator versions: - 3.5.0 - 3.5.01 - 3.5.02 - 3.5.03 - 3.5.04 - 3.5.5 - 3.5.6 - 3.5.7 - 3.5.8 eve: code_size: 2961 commercial_warning: null data_size: 1442578432 data_sources: 1.0.0: dbNSFP v4.9a data_versions: 1.0.0: 1.0.0 datasource: dbNSFP v4.9a description: EVE is a unsupervised model designed to predict the clinical relevance of human single amino acid variants by examining the sequences of various organisms throughout evolutionary history. developer: citation: https://www.nature.com/articles/s41586-021-04043-8 email: support@opencravat.org name: Jonathan Frazer, Pascal Notin, Mafalda Dias organization: University of Oxford website: https://evemodel.org/ groups: [] has_logo: false hidden: false latest_version: 1.0.0 publish_time: 2025-03-07T16:30:45.953148+0000 requires: null size: 1442581393 tags: - variant effect prediction - variants title: EVE type: annotator versions: - 1.0.0 exac_gene: code_size: 17477 commercial_warning: null data_size: 2516996 data_sources: 0.3.1: null 0.3.11: null 0.3.12: null 0.3.13: v0.3.1 0.3.14: v0.3.1 0.3.15: v0.3.1 0.3.16: v0.3.1 0.3.17: v0.3.1 0.3.18: v0.3.1 0.3.19: v0.3.1 0.3.20: v0.3.1 0.3.21: v0.3.1 0.4.0: v0.3.1 data_versions: 0.3.1: 0.3.1 0.3.11: 0.3.1 0.3.12: 0.3.1 0.3.13: 0.3.1 0.3.14: 0.3.1 0.3.15: 0.3.1 0.3.16: 0.3.1 0.3.17: 0.3.1 0.3.18: 0.3.1 0.3.19: 0.3.1 0.3.20: 0.3.1 0.3.21: 0.3.1 0.4.0: 0.4.0 datasource: v0.3.1 description: ExAC Functional Gene Constraint & CNV Scores provides probability of LoF tolerance/intolerance developer: citation: Lek, M., Karczewski, K. J., Minikel, E. V., et al. (2016). Analysis of protein-coding genetic variation in 60,706 humans. Nature, 536(7616), 285. email: support@opencravat.org name: ExAC organization: Exome Aggregation Consortium website: http://exac.broadinstitute.org/ groups: [] has_logo: true hidden: false latest_version: 0.4.0 publish_time: 2019-01-30T18:39:16.427766+0000 requires: null size: 2534473 tags: - genes title: ExAC Gene and CNV type: annotator versions: - 0.3.1 - 0.3.11 - 0.3.12 - 0.3.13 - 0.3.14 - 0.3.15 - 0.3.16 - 0.3.17 - 0.3.18 - 0.3.19 - 0.3.20 - 0.3.21 - 0.4.0 excelreporter: code_size: 1613713 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.4: null 1.0.5: null 1.0.6: null 1.0.7: null 2.1.0: null 2.1.1: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.4: null 1.0.5: null 1.0.6: null 1.0.7: null 2.1.0: null 2.1.1: null datasource: null description: Microsoft Excel reporter developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 2.1.1 publish_time: '2018-08-14T15:05:24.000000' requires: null size: 1613713 tags: - input/output title: Excel Reporter type: reporter versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.4 - 1.0.5 - 1.0.6 - 1.0.7 - 2.1.0 - 2.1.1 fathmm: code_size: 23203 commercial_warning: null data_size: 10401128448 data_sources: 2.3.0: null 2.3.01: null 2.3.02: v2.3 2.3.03: v2.3 2.3.4: v2.3 2.3.5: v2.3 2.3.6: v2.3 2.3.7: v2.3 2.4.0: v2.3 data_versions: 2.3.0: 2.3.0 2.3.01: 2.3.0 2.3.02: 2.3.0 2.3.03: 2.3.0 2.3.4: 2.3.0 2.3.5: 2.3.0 2.3.6: 2.3.0 2.3.7: 2.3.0 2.4.0: 2.3.0 datasource: v2.3 description: Functional analysis through hidden markov models. developer: citation: Shihab, H. A., Gough, J., Mort, M., Cooper, D. N., Day, I. N., & Gaunt, T. R. (2014). Ranking non-synonymous single nucleotide polymorphisms based on disease concepts. Human genomics, 8(1), 11. email: support@opencravat.org name: Chris Campbell organization: University of Bristol Integrative Epidemiology Unit website: http://fathmm.biocompute.org.uk/index.html groups: [] has_logo: true hidden: false latest_version: 2.4.0 publish_time: 2019-01-30T18:39:44.613445+0000 requires: - wgfathmm size: 10401151651 tags: - variant effect prediction - variants - clinical relevance title: FATHMM type: annotator versions: - 2.3.0 - 2.3.01 - 2.3.02 - 2.3.03 - 2.3.4 - 2.3.5 - 2.3.6 - 2.3.7 - 2.4.0 fathmm_mkl: code_size: 126979 commercial_warning: null data_size: 5069600772 data_sources: 1.0.0: v4.1 1.1.0: v4.1 data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: v4.1 description: A database capable of predicting the effects of coding variants using nucleotide-based HMMs. developer: citation: 'Shihab, Hashem A., et al. "An integrative approach to predicting the functional effects of non-coding and coding sequence variation." Bioinformatics 31.10 (2015): 1536-1543.' email: support@opencravat.org name: Chris Campbell organization: University of Bristol Integrative Epidemiology Unit website: http://fathmm.biocompute.org.uk/fathmmMKL.htm groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2024-12-17T20:24:52.181274+0000 requires: null size: 5069727751 tags: - variant effect prediction - variants title: FATHMM MKL type: annotator versions: - 1.0.0 - 1.1.0 fathmm_xf: code_size: 15085 commercial_warning: null data_size: 38602925793 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.0.2: 1.0.0 datasource: null description: Enhanced Accuracy in Predicting the Functional Consequences of Coding Single Nucleotide Variants (SNVs). developer: citation: 'Rogers, Mark F., et al. "Supplementary information for FATHMM-XF: accurate prediction of pathogenic point mutations via extended features." (2015).' email: support@opencravat.org name: Chris Campbell organization: University of Bristol Integrative Epidemiology Unit website: http://fathmm.biocompute.org.uk/fathmm-xf/index.html groups: [] has_logo: false hidden: false latest_version: 1.0.2 publish_time: 2021-06-14T18:10:52.201216+0000 requires: null size: 38602940878 tags: - non coding - variant effect prediction - variants title: FATHMM XF type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.2 fathmm_xf_coding: code_size: 109941 commercial_warning: null data_size: 4061906948 data_sources: 1.0.0: v4.1 1.1.0: v4.1 data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: v4.1 description: Enhanced Accuracy in Predicting the Functional Consequences of Coding Single Nucleotide Variants (SNVs). developer: citation: 'Rogers, Mark F., et al. "Supplementary information for FATHMM-XF: accurate prediction of pathogenic point mutations via extended features." (2015).' email: support@opencravat.org name: Chris Campbell organization: University of Bristol Integrative Epidemiology Unit website: http://fathmm.biocompute.org.uk/fathmm-xf/index.html groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2024-12-17T20:26:44.997483+0000 requires: null size: 4062016889 tags: - variant effect prediction - variants title: FATHMM XF Coding type: annotator versions: - 1.0.0 - 1.1.0 fitcons: code_size: 543247 commercial_warning: null data_size: 4229273604 data_sources: 1.0.0: v4.1 data_versions: 1.0.0: 1.0.0 datasource: v4.1 description: fitCons predicts the fraction of genomic positions belonging to a specific function class that are under selective pressure. developer: citation: 'Gulko, Brad, et al. "A method for calculating probabilities of fitness consequences for point mutations across the human genome." Nature genetics 47.3 (2015): 276-283.' email: support@opencravat.org name: Department of Biological Statistics & Computational Biology, Cornell University organization: Department of Biological Statistics & Computational Biology, Cornell University website: http://compgen.cshl.edu/fitCons/ groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-12-17T20:26:45.061267+0000 requires: null size: 4229816851 tags: - variant effect prediction - variants title: fitCons type: annotator versions: - 1.0.0 flank_seq: code_size: 25696 commercial_warning: null data_size: 6014561977 data_sources: 0.0.1: null 0.0.2: null 0.0.3: null data_versions: 0.0.1: 0.0.1 0.0.2: 0.0.1 0.0.3: 0.0.1 datasource: null description: Reference and alternate bases with flanking sequence developer: citation: Wood, M. A., et al. (2018). neoepiscope Improves Neoepitope Prediction with Multi-variant Phasing. BioRxiv, 418129. email: support@opencravat.org name: Mary Wood organization: Oregon Health and Science University website: https://github.com/pdxgx/neoepiscope groups: [] has_logo: true hidden: false latest_version: 0.0.3 publish_time: 2019-03-07T18:46:08.026166+0000 requires: null size: 6014587673 tags: - variants title: Flanking Sequence type: annotator versions: - 0.0.1 - 0.0.2 - 0.0.3 ftdna-converter: code_size: 30546 commercial_warning: null data_size: 60 data_sources: 1.2.2: null 1.3.0: null 1.3.1: null 1.4.0: null data_versions: 1.2.2: 1.2.2 1.3.0: 1.3.0 1.3.1: 1.3.0 1.4.0: 1.3.0 datasource: null description: Allows user to input files in FamilyTreeDNA format. In both the graphical interface and command line usage, file format will be automatically detected after this converter is installed. developer: citation: '' email: kmoad@insilico.us.com name: Kyle Moad organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: false latest_version: 1.4.0 publish_time: 2020-04-01T10:30:57.549546+0000 requires: - varmeta - vcfinfo>=1.1.5 - hg19wgs size: 30606 tags: - input/output title: FamilyTreeDNA Converter type: converter versions: - 1.2.2 - 1.3.0 - 1.3.1 - 1.4.0 funseq2: code_size: 83300 commercial_warning: null data_size: 33367131186 data_sources: 1.0.0: v2.1.6 1.0.1: v2.1.6 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 datasource: v2.1.6 description: A flexible framework to prioritize regulatory mutations from cancer genome sequencing developer: citation: 'Fu, Y., Liu, Z., Lou, S. et al. FunSeq2: a framework for prioritizing noncoding regulatory variants in cancer. Genome Biol 15, 480 (2014). https://doi.org/10.1186/s13059-014-0480-5' email: support@opencravat.org name: Gerstein Lab organization: Yale University website: http://funseq2.gersteinlab.org/ groups: [] has_logo: true hidden: false latest_version: 1.0.1 publish_time: 2021-04-02T17:17:00.475275+0000 requires: - wgfunseq2 size: 33367214486 tags: - cancer - non coding - variant effect prediction - variants title: FunSeq2 type: annotator versions: - 1.0.0 - 1.0.1 gencode: code_size: 3219765 commercial_warning: null data_size: 349957323 data_sources: 33.0.0: null data_versions: 33.0.0: 33.0.0 datasource: null description: Gene mapper using UCSC Gencode developer: citation: '' email: rkim@oakbioinformatics.com name: Rick Kim organization: Oak Bioinformatics LLC website: http://www.oakbioinformatics.com groups: [] has_logo: false hidden: false latest_version: 33.0.0 publish_time: 2022-01-17T22:42:32.988292+0000 requires: - hg38wgs size: 353177088 tags: null title: Gencode Gene Mapper type: mapper versions: - 33.0.0 genehancer: code_size: 49935 commercial_warning: Freely available for non-commercial use. data_size: 42317828 data_sources: 1.0.0: v4.7 1.1.0: v4.7 data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: v4.7 description: GeneHancer is a database of genome-wide enhancer-to-gene and promoter-to-gene associations. developer: citation: 'Rosen, N., V. Chalifa-Caspi, O. Shmueli, A. Adato, M. Lapidot, J. Stampnitzky, M. Safran, and D. Lancet (2003). GeneLoc: Exon-based integration of human genome maps. Bioinformatics 19(S1). URL: http://genecards.weizmann.ac.il/geneloc' email: support@opencravat.org name: Weizmann Institute of Science organization: Weizmann Institute of Science website: https://genecards.weizmann.ac.il/geneloc_prev/index.shtml groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2020-11-10T20:40:26.352043+0000 requires: - wggenehancer - wgenhancer size: 42367763 tags: - non coding title: GeneHancer type: annotator versions: - 1.0.0 - 1.1.0 genocanyon: code_size: 72465 commercial_warning: null data_size: 4294141956 data_sources: 1.0.0: v4.2 data_versions: 1.0.0: 1.0.0 datasource: v4.2 description: GenoCanyon is a whole-genome functional annotation approach based on unsupervised statistical learning. It integrates genomic conservation measures and biochemical annotation data to predict the functional potential at each nucleotid. developer: citation: Lu, Q., Hu, Y., Sun, J. et al. A Statistical Framework to Predict Functional Non-Coding Regions in the Human Genome Through Integrated Analysis of Annotation Data. Sci Rep 5, 10576 (2015). https://doi.org/10.1038/srep10576 email: support@opencravat.org name: '' organization: Yale University website: http://zhaocenter.org/GenoCanyon_Index.html groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-12-17T20:28:38.047419+0000 requires: null size: 4294214421 tags: - non coding title: GenoCanyon type: annotator versions: - 1.0.0 gerp: code_size: 16023 commercial_warning: null data_size: 4685320192 data_sources: 3.5.0: null 3.5.01: null 3.5.02: null 3.5.03: dbNSFP v4.0b1 3.5.04: dbNSFP v4.0b1 3.5.5: dbNSFP v4.0b1 3.5.6: dbNSFP v4.0b1 3.6.1: dbNSFP v4.0b1 3.6.2: dbNSFP v4.0b1 3.7.0: dbNSFP v4.0b1 data_versions: 3.5.0: 3.5.0 3.5.01: 3.5.0 3.5.02: 3.5.0 3.5.03: 3.5.0 3.5.04: 3.5.0 3.5.5: 3.5.0 3.5.6: 3.5.0 3.6.1: 3.5.0 3.6.2: 3.5.0 3.7.0: 3.5.0 datasource: dbNSFP v4.0b1 description: Genomic Evolutionary Rate Profiling developer: citation: Davydov, E. V., Goode, D. L., Sirota, M., Cooper, G. M., Sidow, A., & Batzoglou, S. (2010). Identifying a high fraction of the human genome to be under selective constraint using GERP++. PLoS computational biology, 6(12), e1001025. email: support@opencravat.org name: Stanford University Sidow Lab organization: Stanford University Sidow Lab website: http://mendel.stanford.edu/SidowLab/downloads/gerp/index.html groups: [] has_logo: true hidden: false latest_version: 3.7.0 publish_time: 2019-01-30T18:39:54.218255+0000 requires: - wggerp size: 4685336215 tags: - variant effect prediction - variants - evolution - clinical relevance title: GERP++ type: annotator versions: - 3.5.0 - 3.5.01 - 3.5.02 - 3.5.03 - 3.5.04 - 3.5.5 - 3.5.6 - 3.6.1 - 3.6.2 - 3.7.0 geuvadis: code_size: 26473 commercial_warning: null data_size: 262144 data_sources: 0.0.1: null data_versions: 0.0.1: 0.0.1 datasource: null description: Significant snp-gene associations reported by the Geuvadis project developer: citation: 'Lappalainen, Tuuli, et al. "Transcriptome and genome sequencing uncovers functional variation in humans." Nature 501.7468 (2013): 506-511.' email: support@opencravat.org name: In Silico Solutions organization: dbNSFP website: https://sites.google.com/site/jpopgen/dbNSFP groups: [] has_logo: true hidden: false latest_version: 0.0.1 publish_time: 2024-12-17T20:28:38.098203+0000 requires: null size: 288617 tags: - variants title: Geuvadis eQTLs type: annotator versions: - 0.0.1 ghis: code_size: 24498 commercial_warning: null data_size: 681988 data_sources: 3.5.0: null 3.5.01: null 3.5.02: dbNSFP v4.0b1 3.5.03: dbNSFP v4.0b1 3.5.4: dbNSFP v4.0b1 3.5.5: dbNSFP v4.0b1 3.6.0: dbNSFP v4.0b1 data_versions: 3.5.0: 3.5.0 3.5.01: 3.5.0 3.5.02: 3.5.0 3.5.03: 3.5.0 3.5.4: 3.5.0 3.5.5: 3.5.0 3.6.0: 3.6.0 datasource: dbNSFP v4.0b1 description: Gene haploinsufficiency scoring developer: citation: Steinberg, J., Honti, F., Meader, S., & Webber, C. (2015). Haploinsufficiency predictions without study bias. Nucleic acids research, 43(15), e101-e101. email: support@opencravat.org name: Julia Steinberg, Frantisek Honti, Stephen Meader, Caleb Webber organization: 1MRC Functional Genomics Unit, University of Oxford website: https://doi.org/10.1093/nar/gkv474 groups: [] has_logo: true hidden: false latest_version: 3.6.0 publish_time: 2019-01-30T18:40:02.446704+0000 requires: - wgghis size: 706486 tags: - genes title: GHIS type: annotator versions: - 3.5.0 - 3.5.01 - 3.5.02 - 3.5.03 - 3.5.4 - 3.5.5 - 3.6.0 gmvp: code_size: 2822 commercial_warning: null data_size: 8132075520 data_sources: 1.0.0: dbNSFP v4.9a data_versions: 1.0.0: 1.0.0 datasource: dbNSFP v4.9a description: gMVP is a graph attention neural network developer: citation: https://www.nature.com/articles/s42256-022-00561-w email: support@opencravat.org name: Haicang Zhang organization: Columbia University website: https://github.com/ShenLab/gMVP groups: [] has_logo: false hidden: false latest_version: 1.0.0 publish_time: 2025-03-07T16:18:47.673511+0000 requires: null size: 8132078342 tags: - variant effect prediction - variants title: gMVP type: annotator versions: - 1.0.0 gnomad: code_size: 169521 commercial_warning: null data_size: 17426890752 data_sources: 2.0.2: null '2.1': null 2.1.0: null 2.1.01: null 2.1.02: null 2.1.03: v2.1 2.1.04: v2.1 2.1.5: v2.1 2.1.6: v2.1 2.1.7: v2.1 2.1.8: v2.1 2.2.0: v2.1 data_versions: 2.0.2: 2.0.2 '2.1': '2.1' 2.1.0: '2.1' 2.1.01: '2.1' 2.1.02: '2.1' 2.1.03: '2.1' 2.1.04: '2.1' 2.1.5: '2.1' 2.1.6: '2.1' 2.1.7: '2.1' 2.1.8: '2.1' 2.2.0: '2.1' datasource: v2.1 description: Genome Aggregation Database (gnomAD) is a resource developed by an international coalition of investigators, with the goal of aggregating and harmonizing both exome and genome sequencing data from a wide variety of large-scale sequencing projects developer: citation: Lek, M., Karczewski, K. J., Minikel, E. V., et al. (2016). Analysis of protein-coding genetic variation in 60,706 humans. Nature, 536(7616), 285. email: '' name: Broad Institute organization: Broad Institute website: http://gnomad.broadinstitute.org/ groups: [] has_logo: true hidden: false latest_version: 2.2.0 publish_time: 2019-01-30T18:40:12.357216+0000 requires: - wggnomad - wgallelefrequency size: 17427060273 tags: - allele frequency title: gnomAD type: annotator versions: - 2.0.2 - '2.1' - 2.1.0 - 2.1.01 - 2.1.02 - 2.1.03 - 2.1.04 - 2.1.5 - 2.1.6 - 2.1.7 - 2.1.8 - 2.2.0 gnomad3: code_size: 166721 commercial_warning: null data_size: 44017865728 data_sources: 1.0.0: v3 1.1.0: v3 data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: v3 description: Genome Aggregation Database (gnomAD) is a resource developed by an international coalition of investigators, with the goal of aggregating and harmonizing both exome and genome sequencing data from a wide variety of large-scale sequencing projects developer: citation: Karczewski, Konrad J., et al. "The Mutational Constraint Spectrum Quantified from Variation in 141,456 Humans." BioRxiv, Apr. 2020, p. 531210. www.biorxiv.org, doi:10.1101/531210. email: '' name: Broad Institute organization: Broad Institute website: http://gnomad.broadinstitute.org/ groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2020-08-21T18:53:57.553853+0000 requires: - wggnomad3 size: 44018032449 tags: - allele frequency title: gnomAD3 type: annotator versions: - 1.0.0 - 1.1.0 gnomad3_counts: code_size: 98986 commercial_warning: null data_size: 3635828740 data_sources: 1.0.0: v3.1 1.1.0: v3.1 data_versions: 1.0.0: 1.0.0 1.1.0: 1.1.0 datasource: v3.1 description: Genome Aggregation Database (gnomAD) is a resource developed by an international coalition of investigators, with the goal of aggregating and harmonizing both exome and genome sequencing data from a wide variety of large-scale sequencing projects developer: citation: Karczewski, Konrad J., et al. "The Mutational Constraint Spectrum Quantified from Variation in 141,456 Humans." BioRxiv, Apr. 2020, p. 531210. www.biorxiv.org, doi:10.1101/531210. email: '' name: Broad Institute organization: Broad Institute website: http://gnomad.broadinstitute.org/ groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2021-06-28T13:22:16.519131+0000 requires: null size: 3635927726 tags: - allele frequency title: gnomAD3 Counts type: annotator versions: - 1.0.0 - 1.1.0 gnomad4: code_size: 171618 commercial_warning: null data_size: 17530655476 data_sources: 4.1.0: v4.1 4.1.1: v4.1 4.1.2: v4.1 data_versions: 4.1.0: 4.1.0 4.1.1: 4.1.1 4.1.2: 4.1.2 datasource: v4.1 description: Genome Aggregation Database (gnomAD) is a resource developed by an international coalition of investigators, with the goal of aggregating and harmonizing both exome and genome sequencing data from a wide variety of large-scale sequencing projects developer: citation: https://doi.org/10.1038/s41586-023-06045-0 email: support@opencravat.org name: Broad Institute organization: Broad Institute website: http://gnomad.broadinstitute.org/ groups: [] has_logo: true hidden: false latest_version: 4.1.2 publish_time: 2024-09-06T19:03:59.716829+0000 requires: null size: 17530827094 tags: - allele frequency title: gnomAD4 type: annotator versions: - 4.1.0 - 4.1.1 - 4.1.2 gnomad_gene: code_size: 180687 commercial_warning: null data_size: 10373124 data_sources: 2.1.03: null 2.1.04: v2.1 2.1.5: v2.1 2.1.6: v2.1 2.1.7: v2.1 2.1.8: v2.1 2.2.0: v2.1 2.2.1: v2.1 data_versions: 2.1.03: 2.1.03 2.1.04: 2.1.03 2.1.5: 2.1.03 2.1.6: 2.1.03 2.1.7: 2.1.03 2.1.8: 2.1.03 2.2.0: 2.2.0 2.2.1: 2.2.0 datasource: v2.1 description: Gene level population statistics from gnomAD developer: citation: https://www.nature.com/articles/nature19057 email: support@opencravat.org name: Broad Institute organization: Broad Institute website: http://gnomad.broadinstitute.org/ groups: [] has_logo: true hidden: false latest_version: 2.2.1 publish_time: 2019-01-30T18:40:20.370464+0000 requires: - wggnomad_gene size: 10553811 tags: - allele frequency - genes title: gnomAD Gene type: annotator versions: - 2.1.03 - 2.1.04 - 2.1.5 - 2.1.6 - 2.1.7 - 2.1.8 - 2.2.0 - 2.2.1 go: code_size: 1509467 commercial_warning: null data_size: 48205824 data_sources: 2018.03.08: null 2018.12.02: null 2018.12.021: null 2018.12.022: 2018.12.06 2018.12.023: 2018.12.06 2019.03.20: 2018.12.06 2019.05.13: 2018.12.06 2019.08.02: 2018.12.06 2019.08.16: 2018.12.06 2019.2.006: 2018.12.06 2020.12.03: 2020.12.03 2021.02.04: 2020.12.03 2022.02.01: 2023.02.01 2022.10.05: 2022.10.05 2022.11.01: 2023.01.01 2024.02.01: 2024.02.01 2024.05.01: 2024.05.01 2024.12.10: 2024.12.10 2025.03.01: 2025.03.01 2025.04.01: 2025.04.01 2025.07.01: 2025.07.01 data_versions: 2018.03.08: 2018.03.08 2018.12.02: 2018.03.08 2018.12.021: 2018.12.021 2018.12.022: 2018.12.021 2018.12.023: 2018.12.021 2019.03.20: 2018.12.021 2019.05.13: 2018.12.021 2019.08.02: 2018.12.021 2019.08.16: 2018.12.021 2019.2.006: 2018.12.021 2020.12.03: 2020.12.03 2021.02.04: 2021.02.04 2022.02.01: 2022.02.01 2022.10.05: 2022.10.05 2022.11.01: 2022.11.01 2024.02.01: 2024.02.01 2024.05.01: 2024.05.01 2024.12.10: 2024.12.10 2025.03.01: 2025.03.01 2025.04.01: 2025.04.01 2025.07.01: 2025.07.01 datasource: 2025.07.01 description: Gene Ontology (GO) project provides a comprehensive computable knowledge regarding the functions of genes and gene products. developer: citation: 'Ashburner, M., Ball, C. A., Blake, J. A., et al. (2000). Gene Ontology: tool for the unification of biology. Nature genetics, 25(1), 25.' email: support@opencravat.org name: Gene Ontology Consortium organization: Gene Ontology Consortium website: http://geneontology.org/ groups: [] has_logo: true hidden: false latest_version: 2025.07.01 publish_time: 2025-07-08T15:12:50.498264+0000 requires: - wggo size: 49715291 tags: - genes title: Gene Ontology type: annotator versions: - 2018.03.08 - 2018.12.02 - 2018.12.021 - 2018.12.022 - 2018.12.023 - 2019.2.006 - 2019.03.20 - 2019.05.13 - 2019.08.02 - 2019.08.16 - 2020.12.03 - 2021.02.04 - 2022.02.01 - 2022.10.05 - 2022.11.01 - 2024.02.01 - 2024.05.01 - 2024.12.10 - 2025.03.01 - 2025.04.01 - 2025.07.01 grasp: code_size: 123965 commercial_warning: 'For commercial use, contact johnsonad2@nhlbi.nih.gov. ' data_size: 714883072 data_sources: 2.0.0: null 2.0.1: null 2.0.2: null 2.0.3: null 2.0.4: v2.0.0.0 2.0.5: v2.0.0.0 2.0.6: v2.0.0.0 2.0.7: v2.0.0.0 2.0.8: v2.0.0.0 data_versions: 2.0.0: 2.0.0 2.0.1: 2.0.1 2.0.2: 2.0.2 2.0.3: 2.0.2 2.0.4: 2.0.2 2.0.5: 2.0.2 2.0.6: 2.0.2 2.0.7: 2.0.2 2.0.8: 2.0.2 datasource: v2.0.0.0 description: Genome-Wide Repository of Associations Between SNPs and Phenotypes developer: citation: "Leslie R, O\u2019Donnell CJ, Johnson AD (2014) GRASP: analysis of genotype-phenotype\ \ results from 1,390 genome-wide association studies and corresponding open\ \ access database. Bioinformatics 30(12), i185-94" email: support@opencravat.org name: NIH organization: NIH website: https://grasp.nhlbi.nih.gov/Overview.aspx groups: [] has_logo: true hidden: false latest_version: 2.0.8 publish_time: 2019-01-30T18:41:07.241162+0000 requires: - wggrasp size: 715007037 tags: - variants - non coding - clinical relevance - literature title: GRASP type: annotator versions: - 2.0.0 - 2.0.1 - 2.0.2 - 2.0.3 - 2.0.4 - 2.0.5 - 2.0.6 - 2.0.7 - 2.0.8 gtex: code_size: 17212 commercial_warning: null data_size: 18395136 data_sources: 6.0.0: null 6.0.01: null 7.0.0: null 7.0.1: v7 7.0.2: v7 7.0.3: v7 7.0.4: v7 8.0.0: v8 data_versions: 6.0.0: 6.0.0 6.0.01: 6.0.0 7.0.0: 6.0.0 7.0.1: 7.0.1 7.0.2: 7.0.1 7.0.3: 7.0.1 7.0.4: 7.0.1 8.0.0: 8.0.0 datasource: v8 description: Genotype-tissue expression developer: citation: https://gtexportal.org/home/faq#citePortal email: support@opencravat.org name: GTEx Consortium organization: The Broad Institute of MIT and Harvard website: https://gtexportal.org/home/ groups: [] has_logo: true hidden: false latest_version: 8.0.0 publish_time: 2024-12-17T20:32:24.803420+0000 requires: - wggtex size: 18412348 tags: - variants title: GTEx eQTLs type: annotator versions: - 6.0.0 - 6.0.01 - 7.0.0 - 7.0.1 - 7.0.2 - 7.0.3 - 7.0.4 - 8.0.0 gwas_catalog: code_size: 128069 commercial_warning: null data_size: 189739008 data_sources: 1.0.0: null 2025.07.02: 2025.07.02 2025.07.07: 2025.07.02 data_versions: 1.0.0: 1.0.0 2025.07.02: 2025.07.02 2025.07.07: 2025.07.02 datasource: 2025.07.02 description: GWAS Catalog Annotator developer: citation: 'Buniello A, MacArthur JAL, Cerezo M, Harris LW, Hayhurst J, Malangone C, McMahon A, Morales J, Mountjoy E, Sollis E, Suveges D, Vrousgou O, Whetzel PL, Amode R, Guillen JA, Riat HS, Trevanion SJ, Hall P, Junkins H, Flicek P, Burdett T, Hindorff LA, Cunningham F and Parkinson H. The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019. Nucleic Acids Research, 2019, Vol. 47 (Database issue): D1005-D1012.' email: gwas-info@ebi.ac.uk. name: NHGRI-EBI organization: NHGRI-EBI website: https://www.ebi.ac.uk/gwas/home groups: [] has_logo: true hidden: false latest_version: 2025.07.07 publish_time: 2025-07-02T20:43:14.304714+0000 requires: - wggwas_catalog size: 189867077 tags: - variants - non coding - clinical relevance - literature title: GWAS Catalog type: annotator versions: - 1.0.0 - 2025.07.02 - 2025.07.07 haploreg_afr: code_size: 9959 commercial_warning: null data_size: 10396768256 data_sources: 1.0.0: v4.1 1.1.0: v4.1 data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: v4.1 description: SNPs in LD with the variant in African populations developer: citation: "Lucas D. Ward, Manolis Kellis, HaploReg: a resource for exploring chromatin\ \ states, conservation, and regulatory motif alterations within sets of genetically\ \ linked variants, Nucleic Acids Research, Volume 40, Issue D1, 1 January 2012,\ \ Pages D930\u2013D934, https://doi.org/10.1093/nar/gkr917" email: luke@lukeward.net name: Luke Ward organization: MIT Kellis Lab website: https://pubs.broadinstitute.org/mammals/haploreg/haploreg.php groups: - haploreg_group has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2020-12-03T16:58:47.649809+0000 requires: - dbsnp - wghaploreg_afr size: 10396778215 tags: - non coding - variants title: HaploReg African type: annotator versions: - 1.0.0 - 1.1.0 haploreg_amr: code_size: 9934 commercial_warning: null data_size: 15905863680 data_sources: 1.0.0: v4.1 1.1.0: v4.1 data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: v4.1 description: SNPs in LD with the variant in American populations developer: citation: "Lucas D. Ward, Manolis Kellis, HaploReg: a resource for exploring chromatin\ \ states, conservation, and regulatory motif alterations within sets of genetically\ \ linked variants, Nucleic Acids Research, Volume 40, Issue D1, 1 January 2012,\ \ Pages D930\u2013D934, https://doi.org/10.1093/nar/gkr917" email: luke@lukeward.net name: Luke Ward organization: MIT Kellis Lab website: https://pubs.broadinstitute.org/mammals/haploreg/haploreg.php groups: - haploreg_group has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2020-12-03T17:26:28.706126+0000 requires: - dbsnp - wghaploreg_amr size: 15905873614 tags: - non coding - variants title: HaploReg American type: annotator versions: - 1.0.0 - 1.1.0 haploreg_asn: code_size: 10034 commercial_warning: null data_size: 12917386240 data_sources: 1.0.0: v4.1 1.1.0: v4.1 data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: v4.1 description: SNPs in LD with the variant in Asian populations developer: citation: "Lucas D. Ward, Manolis Kellis, HaploReg: a resource for exploring chromatin\ \ states, conservation, and regulatory motif alterations within sets of genetically\ \ linked variants, Nucleic Acids Research, Volume 40, Issue D1, 1 January 2012,\ \ Pages D930\u2013D934, https://doi.org/10.1093/nar/gkr917" email: luke@lukeward.net name: Luke Ward organization: MIT Kellis Lab website: https://pubs.broadinstitute.org/mammals/haploreg/haploreg.php groups: - haploreg_group has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2020-12-31T14:47:03.039024+0000 requires: - dbsnp - wghaploreg_asn size: 12917396274 tags: - non coding - variants title: HaploReg Asian type: annotator versions: - 1.0.0 - 1.1.0 haploreg_eur: code_size: 9993 commercial_warning: null data_size: 15219340288 data_sources: 1.0.0: v4.1 1.1.0: v4.1 data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: v4.1 description: SNPs in LD with the variant in European populations developer: citation: "Lucas D. Ward, Manolis Kellis, HaploReg: a resource for exploring chromatin\ \ states, conservation, and regulatory motif alterations within sets of genetically\ \ linked variants, Nucleic Acids Research, Volume 40, Issue D1, 1 January 2012,\ \ Pages D930\u2013D934, https://doi.org/10.1093/nar/gkr917" email: luke@lukeward.net name: Luke Ward organization: MIT Kellis Lab website: https://pubs.broadinstitute.org/mammals/haploreg/haploreg.php groups: - haploreg_group has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2020-12-03T17:43:34.345345+0000 requires: - dbsnp - wghaploreg_eur size: 15219350281 tags: - non coding - variants title: HaploReg European type: annotator versions: - 1.0.0 - 1.1.0 haploreg_group: code_size: 4329 commercial_warning: null data_size: 0 data_sources: 1.0.0: v4.1 data_versions: 1.0.0: null datasource: v4.1 description: SNPs in LD with the variant developer: citation: "Lucas D. Ward, Manolis Kellis, HaploReg: a resource for exploring chromatin\ \ states, conservation, and regulatory motif alterations within sets of genetically\ \ linked variants, Nucleic Acids Research, Volume 40, Issue D1, 1 January 2012,\ \ Pages D930\u2013D934, https://doi.org/10.1093/nar/gkr917" email: luke@lukeward.net name: Luke Ward organization: MIT Kellis Lab website: https://pubs.broadinstitute.org/mammals/haploreg/haploreg.php groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2020-08-21T18:59:04.386705+0000 requires: null size: 4329 tags: - non coding title: HaploReg type: group versions: - 1.0.0 hereditary_cancer: code_size: 343564 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: Reports on variants in a gene list implicated in nine hereditary cancer types by the Cancer Gene Census developer: citation: '' email: support@opencravat.org name: OpenCRAVAT Team organization: KarchinLab website: https://opencravat.org groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2023-04-13T20:13:15.610259+0000 requires: - clinvar - cosmic - dbsnp - gnomad3 - cgc size: 343564 tags: null title: Hereditary Cancer type: package versions: - 1.0.0 - 1.1.0 hg19: code_size: 25574 commercial_warning: null data_size: 3915120 data_sources: 1.0.4: null 1.0.5: null 1.0.6: null data_versions: 1.0.4: 1.0.4 1.0.5: 1.0.4 1.0.6: 1.0.4 datasource: null description: Input coordinates are mapped to hg19 through liftOver. developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: https://github.com/KarchinLab/open-cravat-modules-karchinlab groups: [] has_logo: true hidden: false latest_version: 1.0.6 publish_time: 2019-11-26T19:57:36.190745+0000 requires: null size: 3940694 tags: - variants title: hg19 coordinates type: annotator versions: - 1.0.4 - 1.0.5 - 1.0.6 hg19wgs: code_size: 2209 commercial_warning: null data_size: 816241703 data_sources: 1.0.0: null data_versions: 1.0.0: 1.0.0 datasource: null description: UCSC hg19 whole genome sequence module developer: citation: '' email: support@cravat.su name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.0 publish_time: 2020-05-18T19:08:14.663706+0000 requires: null size: 816243912 tags: null title: UCSC hg19 Whole Genome Sequence type: common versions: - 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hg38wgs size: 732028756 tags: null title: UCSC hg38 Gene Mapper type: mapper versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.1.0 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.1.5 - 1.1.6 - 1.1.7 - 1.1.8 - 1.1.9 - 1.2.0 - 1.2.5 - 1.2.7 - 1.5.0 - 1.5.1 - 1.5.2 - 1.5.3 - 1.5.4 - 1.5.5 - 1.5.6 - 1.5.7 - 1.5.8 - 1.7.3 - 1.7.4 - 1.7.5 - 1.7.6 - 1.7.7 - 1.7.8 - 1.7.9 - 1.9.0 - 1.9.1 - 1.9.2 - 1.9.3 - 1.9.4 - 1.9.5 - 1.9.6 - 1.9.7 - 1.9.8 - 1.9.9 - 1.9.10 - 1.10.0 - 1.10.1 - 1.10.2 - 1.10.3 - 1.10.4 - 1.11.0 - 1.47.0 hg38wgs: code_size: 2240 commercial_warning: null data_size: 835393456 data_sources: 1.0.0: null data_versions: 1.0.0: 1.0.0 datasource: null description: UCSC hg38 whole genome sequence module developer: citation: '' email: support@cravat.su name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.0 publish_time: 2020-05-18T19:08:58.046364+0000 requires: null size: 835395696 tags: null title: UCSC hg38 Whole Genome Sequence type: common versions: - 1.0.0 hgdp: code_size: 1998931 commercial_warning: 'For academic use only. ' data_size: 61444096 data_sources: 1.0.0: null data_versions: 1.0.0: 1.0.0 datasource: null description: Human Genome Diversity Panel (HGDP) DNA from individuals among 51 different populations. developer: citation: '' email: '' name: Jun Z. Li et al. organization: Stanford University School of Medicine website: https://www.hagsc.org/hgdp/ groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2021-06-28T21:36:06.657764+0000 requires: null size: 63443027 tags: - allele frequency title: HGDP type: annotator versions: - 1.0.0 hgvs: code_size: 118430 commercial_warning: null data_size: 205697024 data_sources: 1.0.0: null 1.0.1: null 1.0.2: v15.11 1.0.3: v15.11 1.0.4: v15.11 1.0.5: v15.11 1.0.6: v15.11 1.0.7: v15.11 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.0.2: 1.0.0 1.0.3: 1.0.0 1.0.4: 1.0.0 1.0.5: 1.0.0 1.0.6: 1.0.0 1.0.7: 1.0.0 datasource: v15.11 description: Variants described in HGVS format developer: citation: 'den Dunnen, J. T., Dalgleish, R., Maglott, D. R., et al. (2016). HGVS recommendations for the description of sequence variants: 2016 update. Human mutation, 37(6), 564-569.' email: support@cravat.us name: Human Genome Variation Society organization: Human Genome Variation Society website: http://www.hgvs.org/ groups: [] has_logo: true hidden: false latest_version: 1.0.7 publish_time: 2019-01-30T18:41:41.109583+0000 requires: - wghgvs size: 205815454 tags: - variants title: HGVS Format type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.0.5 - 1.0.6 - 1.0.7 hgvs-converter: code_size: 207880 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: File converter for HGVS string input developer: citation: '' email: kanderson@potomacitgroup.com name: Kyle Anderson organization: Potomac IT Group website: https://potomacitgroup.com/ groups: [] has_logo: false hidden: false latest_version: 1.1.0 publish_time: 2024-05-02T19:18:12.209970+0000 requires: null size: 207880 tags: null title: HGVS Converter type: converter versions: - 1.0.0 - 1.1.0 hpo: code_size: 760486 commercial_warning: null data_size: 18767872 data_sources: 1.0.0: April 2021 2.0.0: November 2022 2.1.0: February 2024 2.1.1: April 2024 2.1.2: May 2024 2.1.3: August 2024 2024.12.10: 2024.12.10 2025.02.01: 2025.02.01 2025.04.01: 2025.04.01 2025.06.01: 2025.06.01 data_versions: 1.0.0: 1.0.0 2.0.0: 2.0.0 2.1.0: 2.1.0 2.1.1: 2.1.1 2.1.2: 2.1.2 2.1.3: 2.1.3 2024.12.10: 2024.12.10 2025.02.01: 2025.02.01 2025.04.01: 2025.04.01 2025.06.01: 2025.06.01 datasource: 2025.06.01 description: The Human Phenotype Ontology (HPO) provides a standardized vocabulary of phenotypic abnormalities encountered in human disease. Each term in the HPO describes a phenotypic abnormality. developer: citation: 'Koehler, Sebastian et al. The Human Phenotype Ontology in 2021.Nucleic acids research vol. 49,D1 (2021): D1207-D1217. doi:10.1093/nar/gkaa1043' email: support@opencravat.org name: '' organization: The Jackson Laboratory website: https://hpo.jax.org/app/ groups: [] has_logo: true hidden: false latest_version: 2025.06.01 publish_time: 2025-06-05T19:09:47.466497+0000 requires: - wghpo size: 19528358 tags: - genes title: Human Phenotype Ontology type: annotator versions: - 1.0.0 - 2.0.0 - 2.1.0 - 2.1.1 - 2.1.2 - 2.1.3 - 2024.12.10 - 2025.02.01 - 2025.04.01 - 2025.06.01 intact: code_size: 52593 commercial_warning: null data_size: 8708096 data_sources: 2018.11.30: 4.0.0 2019.03.20: 2018.11.30 2019.05.13: 2018.11.30 2019.08.23: 2018.11.30 2019.1.24: 4.0.0 2019.1.25: 2018.11.30 2019.2.06: 2018.11.30 data_versions: 2018.11.30: 2018.11.30 2019.03.20: 2018.11.30 2019.05.13: 2018.11.30 2019.08.23: 2018.11.30 2019.1.24: 2018.11.30 2019.1.25: 2018.11.30 2019.2.06: 2018.11.30 datasource: 2018.11.30 description: Molecular interaction data developer: citation: "Orchard, S., Ammari, M., Aranda, B., et al. (2013). The MIntAct project\xE2\ \u20AC\u201DIntAct as a common curation platform for 11 molecular interaction\ \ databases. Nucleic acids research, 42(D1), D358-D363." email: support@opencravat.org name: Orchard S et al. organization: European Bioinformatics Institute (EMBL-EBI) website: https://www.ebi.ac.uk/intact/ groups: [] has_logo: true hidden: false latest_version: 2019.08.23 publish_time: 2019-01-30T18:41:50.829659+0000 requires: - wgintact size: 8760689 tags: - genes title: IntAct type: annotator versions: - 2018.11.30 - 2019.1.24 - 2019.1.25 - 2019.2.06 - 2019.03.20 - 2019.05.13 - 2019.08.23 interpro: code_size: 148308 commercial_warning: null data_size: 7279765508 data_sources: 71.0.0: 4.0.0 71.0.1: v71 71.0.2: v71 71.0.3: v71 71.0.4: v71 71.0.5: v71 71.0.6: v71 71.1.0: v71 71.2.0: v71 71.3.0: v71 data_versions: 71.0.0: 71.0.0 71.0.1: 71.0.0 71.0.2: 71.0.0 71.0.3: 71.0.0 71.0.4: 71.0.0 71.0.5: 71.0.0 71.0.6: 71.0.0 71.1.0: 71.1.0 71.2.0: 71.1.0 71.3.0: 71.3.0 datasource: v71 description: Protein sequence analysis & classification developer: citation: 'Mitchell, A. L., Attwood, T. K., Babbitt, P. C., et al. (2018). InterPro in 2019: improving coverage, classification and access to protein sequence annotations. Nucleic acids research, 47(D1), D351-D360.' email: support@cravat.us name: Alex L. Mitchell et al. organization: European Bioinformatics Institute (EMBL-EBI) website: https://www.ebi.ac.uk/interpro/ groups: [] has_logo: true hidden: false latest_version: 71.3.0 publish_time: 2019-01-30T18:41:58.811979+0000 requires: - wginterpro size: 7279913816 tags: - genes title: InterPro type: annotator versions: - 71.0.0 - 71.0.1 - 71.0.2 - 71.0.3 - 71.0.4 - 71.0.5 - 71.0.6 - 71.1.0 - 71.2.0 - 71.3.0 javierre_promoters: code_size: 32060 commercial_warning: null data_size: 522331 data_sources: 2019.03.20: November 17, 2016 2019.05.20: November 17, 2016 2019.2.13: November 17, 2016 2019.2.22: November 17, 2016 2019.2.5: November 17, 2016 2019.3.12: November 17, 2016 2022.12.12: November 17, 2016 data_versions: 2019.03.20: 2019.2.5 2019.05.20: 2019.05.20 2019.2.13: 2019.2.5 2019.2.22: 2019.2.5 2019.2.5: 2019.2.5 2019.3.12: 2019.2.5 2022.12.12: 2019.05.20 datasource: November 17, 2016 description: Javierre et al promoter-interacting regions | Promoter capture Hi-C was used to identify interacting regions of 31,253 promoters that are significantly associated across 17 human primary hematopoietic cell types. developer: citation: Javierre, B. M., Burren S.E. et al. (2016). Lineage-specific genome architecture links enhancers and non-coding disease variants to target gene promoters. Cell, 167(5), 1369-1384. email: null name: null organization: The Babraham Institute, Babraham Research Campus, Cambridge website: https://doi.org/10.1016/j.cell.2016.09.037 groups: [] has_logo: true hidden: false latest_version: 2022.12.12 publish_time: 2019-02-11T20:29:36.950176+0000 requires: null size: 554391 tags: - genes - non coding - functional studies title: Promoter IR type: annotator versions: - 2019.2.5 - 2019.2.13 - 2019.2.22 - 2019.3.12 - 2019.03.20 - 2019.05.20 - 2022.12.12 linsight: code_size: 144517 commercial_warning: For commercial use, contact xmliu.uth@gmail.com data_size: 9191047168 data_sources: 1.0.0: null 2018.10.19: 2018.10.19 2018.10.191: 2018.10.19 2018.10.192: 2018.10.19 2019.02.006: 2018.10.19 2019.03.20: 2018.10.19 2019.05.13: 2018.10.19 2021.01.08: 2018.10.19 data_versions: 1.0.0: 1.0.0 2018.10.19: 2018.10.19 2018.10.191: 2018.10.19 2018.10.192: 2018.10.19 2019.02.006: 2018.10.19 2019.03.20: 2018.10.19 2019.05.13: 2018.10.19 2021.01.08: 2018.10.19 datasource: 2018.10.19 description: LINSIGHT developer: citation: Huang, Y. F., Gulko, B., & Siepel, A. (2017). Fast, scalable prediction of deleterious noncoding variants from functional and population genomic data. Nature genetics, 49(4), 618. email: asiepel@cshl.edu name: Adam Siepel organization: Cold Spring Harbor Laboratory website: http://github.com/CshlSiepelLab/LINSIGHT/blob/master/README.md groups: [] has_logo: true hidden: false latest_version: 2021.01.08 publish_time: '2018-11-01T20:59:34.000000' requires: null size: 9191191685 tags: - evolution - non coding - variant effect prediction - variants title: LINSIGHT type: annotator versions: - 1.0.0 - 2018.10.19 - 2018.10.191 - 2018.10.192 - 2019.02.006 - 2019.03.20 - 2019.05.13 - 2021.01.08 litvar: code_size: 363100 commercial_warning: null data_size: 0 data_sources: 1.0.0: Live 1.1.0: Live 1.2.0: Live data_versions: 1.0.0: null 1.1.0: null 1.2.0: null datasource: Live description: LitVar allows the search and retrieval of variant relevant information from biomedical literature. developer: citation: 'Allot, Alexis, et al. "LitVar: a semantic search engine for linking genomic variant data in PubMed and PMC." Nucleic acids research 46.W1 (2018): W530-W536.' email: support@opencravat.org name: NCBI organization: NCBI website: https://www.ncbi.nlm.nih.gov/CBBresearch/Lu/Demo/LitVar/#!?query= groups: [] has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-12-03T16:55:04.281555+0000 requires: - dbsnp size: 363100 tags: - literature title: LitVar type: annotator versions: - 1.0.0 - 1.1.0 - 1.2.0 litvar_full: code_size: 354398 commercial_warning: null data_size: 211492864 data_sources: 2.0.0: null data_versions: 2.0.0: 2.0.0 datasource: null description: LitVar allows the search and retrieval of variant relevant information from biomedical literature. developer: citation: 'Allot, Alexis, et al. "LitVar: a semantic search engine for linking genomic variant data in PubMed and PMC." Nucleic acids research 46.W1 (2018): W530-W536.' email: support@opencravat.org name: NCBI organization: NCBI website: https://www.ncbi.nlm.nih.gov/CBBresearch/Lu/Demo/LitVar/#!?query= groups: [] has_logo: true hidden: false latest_version: 2.0.0 publish_time: 2024-03-06T14:54:30.889566+0000 requires: null size: 211847262 tags: - literature - variants title: LitVar Full type: annotator versions: - 2.0.0 loftool: code_size: 15130 commercial_warning: null data_size: 559108 data_sources: 3.5.0: null 3.5.01: null 3.5.02: dbNSFP v4.0b1 3.5.03: dbNSFP v4.0b1 3.5.4: dbNSFP v4.0b1 3.5.5: dbNSFP v4.0b1 3.6.0: dbNSFP v4.0b1 3.6.1: dbNSFP v4.0b1 data_versions: 3.5.0: 3.5.0 3.5.01: 3.5.0 3.5.02: 3.5.0 3.5.03: 3.5.0 3.5.4: 3.5.0 3.5.5: 3.5.0 3.6.0: 3.6.0 3.6.1: 3.6.0 datasource: dbNSFP v4.0b1 description: Gene intolerance score based on loss-of-function variants developer: citation: 'Fadista, J., Oskolkov, N., Hansson, O., & Groop, L. (2016). LoFtool: a gene intolerance score based on loss-of-function variants in 60 706 individuals. Bioinformatics, 33(4), 471-474.' email: support@opencravat.org name: "Jo\xE3o Fadista, Nikolay Oskolkov, Ola Hansson, Leif Groop" organization: Lund University Diabetes Centre website: https://doi.org/10.1093/bioinformatics/btv602 groups: [] has_logo: true hidden: false latest_version: 3.6.1 publish_time: 2019-01-30T18:42:16.687716+0000 requires: null size: 574238 tags: - genes title: LoFtool type: annotator versions: - 3.5.0 - 3.5.01 - 3.5.02 - 3.5.03 - 3.5.4 - 3.5.5 - 3.6.0 - 3.6.1 lrt: code_size: 79274 commercial_warning: null data_size: 3874093060 data_sources: 1.0.0: v4.1 data_versions: 1.0.0: 1.0.0 datasource: v4.1 description: The likelihood ratio test (LRT) can accurately identify a subset of deleterious mutations that disrupt highly conserved amino acids within protein-coding sequences. developer: citation: 'Chun, Sung, and Justin C. Fay. "Identification of deleterious mutations within three human genomes." Genome research 19.9 (2009): 1553-1561.' email: support@opencravat.org name: Sung Chun and Justin C. Fay organization: Computational Biology Program, University of Washington website: http://www.genetics.wustl.edu/jflab/lrt_query.html groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-12-17T20:34:17.494349+0000 requires: null size: 3874172334 tags: - variant effect prediction - variants title: Likelihood Ratio Test type: annotator versions: - 1.0.0 mavedb: code_size: 50486 commercial_warning: null data_size: 2021380 data_sources: 1.0.0: v1.7.1 1.0.1: v1.7.2 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 datasource: v1.7.2 description: MaveDB is a public repository for datasets from Multiplexed Assays of Variant Effect (MAVEs). developer: citation: 'Esposito, Daniel, et al. "MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect." Genome biology 20.1 (2019): 1-11.' email: support@opencravat.org name: Fowler Lab organization: University of Washington, Department of Genome Sciences website: https://www.mavedb.org/ groups: [] has_logo: true hidden: false latest_version: 1.0.1 publish_time: 2024-12-17T20:34:17.519756+0000 requires: null size: 2071866 tags: - functional studies title: MaveDB type: annotator versions: - 1.0.0 - 1.0.1 metalr: code_size: 245060 commercial_warning: null data_size: 3968645124 data_sources: 1.0.0: v4.1 1.0.1: v4.1 1.0.2: v4.1 1.0.3: v4.1 1.1.0: v4.1 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.0.2: 1.0.0 1.0.3: 1.0.0 1.1.0: 1.0.0 datasource: v4.1 description: MetaLR creates an ensemble-based prediction score by using machine learning and logistic regression. developer: citation: Dong C, Wei P, Jian X, Gibbs R, Boerwinkle E, Wang K* and Liu X*. (2015) Comparison and integration of deleteriousness prediction methods for nonsynonymous SNVs in whole exome sequencing studies. Human Molecular Genetics 24(8):2125-2137. email: support@opencravat.org name: Chengliang Dong organization: University of Southern California, Biostatistics Department website: https://academic.oup.com/hmg/article/24/8/2125/651446 groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2020-09-14T14:59:15.764989+0000 requires: null size: 3968890184 tags: - variant effect prediction - variants title: MetaLR type: annotator versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.1.0 metarnn: code_size: 8408 commercial_warning: null data_size: 9732190208 data_sources: 1.0.0: dbNSFP v4.9a 1.1.0: dbNSFP v4.9a data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: dbNSFP v4.9a description: Recurrent neural network predictor using an ensembl of 16 sub-predictors developer: citation: https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-022-01120-z email: support@opencravat.org name: Chang Li organization: University of South Florida website: http://www.liulab.science/metarnn.html groups: [] has_logo: false hidden: false latest_version: 1.1.0 publish_time: 2025-03-07T16:29:32.221156+0000 requires: null size: 9732198616 tags: - variant effect prediction - variants title: MetaRNN type: annotator versions: - 1.0.0 - 1.1.0 metasvm: code_size: 273848 commercial_warning: null data_size: 3968694276 data_sources: 1.0.0: v4.1 1.0.1: v4.1 1.1.0: v4.1 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.1.0: 1.0.0 datasource: v4.1 description: MetaSVM creates an ensemble-based prediction score by using a support vector machine model. developer: citation: Dong C, Wei P, Jian X, Gibbs R, Boerwinkle E, Wang K* and Liu X*. (2015) Comparison and integration of deleteriousness prediction methods for nonsynonymous SNVs in whole exome sequencing studies. Human Molecular Genetics 24(8):2125-2137. email: support@opencravat.org name: Chengliang Dong organization: University of Southern California, Biostatistics Department website: https://academic.oup.com/hmg/article/24/8/2125/651446 groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2020-09-14T15:00:20.993477+0000 requires: null size: 3968968124 tags: - variant effect prediction - variants title: MetaSVM type: annotator versions: - 1.0.0 - 1.0.1 - 1.1.0 mirbase: code_size: 175884 commercial_warning: null data_size: 468996 data_sources: 1.0.0: v3.0 1.0.1: v3.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 datasource: v3.0 description: A microRNA database is a searchable database of published miRNA sequences and annotation. developer: citation: 'Kozomara, Ana, and Sam Griffiths-Jones. "miRBase: annotating high confidence microRNAs using deep sequencing data." Nucleic acids research 42.D1 (2014): D68-D73' email: mirbase@manchester.ac.uk name: Faculty of Biology, Medicine, and Health, Uninversity of Manchester organization: Faculty of Biology, Medicine, and Health, Uninversity of Manchester website: http://www.mirbase.org/ groups: [] has_logo: true hidden: false latest_version: 1.0.1 publish_time: 2020-08-31T15:01:17.047131+0000 requires: - wgmirbase size: 644880 tags: - non coding title: miRBase type: annotator versions: - 1.0.0 - 1.0.1 mistic: code_size: 105145 commercial_warning: MISTIC is freely available for all non-commercial applications. For a commercial application, please contact here https://lbgi.fr/mistic/contact. data_size: 3279654912 data_sources: 1.0.0: 2021 1.1.0: 2021 data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: 2021 description: A supervised machine-learning model dedicated to the prediction of deleterious missense variants. developer: citation: "Chennen K, Weber T, Lornage X, Kress A, B\xF6hm J, Thompson J, Laporte\ \ J, Poch O. MISTIC: A prediction tool to reveal disease-relevant deleterious\ \ missense variants. 2020 Jul 31;15(7):e0236962. doi: https://doi.org/10.1371/journal.pone.0236962.\ \ eCollection 2020." email: support@opencravat.org name: Kirsley Chennen, Thomas Webber, and Oliver Poch organization: "Facult\xE9 de m\xE9decine de Strasbourg" website: https://lbgi.fr/mistic/ groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2024-08-20T22:44:55.350246+0000 requires: null size: 3279760057 tags: - variants - variant effect prediction title: MISTIC (MISsense deleTeriousness predICtor) type: annotator versions: - 1.0.0 - 1.1.0 mitomap: code_size: 90100 commercial_warning: null data_size: 301060 data_sources: 1.0.0: 2020.04.27 1.1.0: 2020.04.27 1.2.0: 2023.06.21 data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 1.2.0: 1.2.0 datasource: 2023.06.21 description: The MITOMAP database of human mitochondrial DNA (mtDNA) information has been an important compilation of mtDNA variation for researchers, clinicians and genetic counselors. developer: citation: Lott, et al., mtDNA variation and analysis using MITOMAP and MITOMASTER, Current Protocols in Bioinformatics 44:1.23.1-1.23.26 (December 2013). email: support@opencravat.org name: '' organization: FOSWIKI website: https://mitomap.org/foswiki/bin/view/MITOMAP/WebHome groups: [] has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2024-12-17T20:34:17.985169+0000 requires: - wgmitomap size: 391160 tags: - variant effect prediction - variants title: MITOMAP type: annotator versions: - 1.0.0 - 1.1.0 - 1.2.0 mupit: code_size: 286130 commercial_warning: null data_size: 5287936 data_sources: 1.0.0: null 4.1.0: null 4.2.1: null 4.2.2: null 4.2.3: v5.2.4 4.2.4: v5.2.4 4.2.5: v5.2.4 4.2.6: v5.2.4 4.3.0: v5.2.4 4.3.1: v5.2.4 4.3.2: v5.2.4 4.3.3: v5.2.4 data_versions: 1.0.0: 1.0.0 4.1.0: 1.0.0 4.2.1: 1.0.0 4.2.2: 4.2.2 4.2.3: 4.2.2 4.2.4: 4.2.2 4.2.5: 4.2.2 4.2.6: 4.2.2 4.3.0: 4.2.2 4.3.1: 4.2.2 4.3.2: 4.2.2 4.3.3: 4.2.2 datasource: v5.2.4 description: Provides links to variant position and annotations in 3D MuPIT structure viewer. developer: citation: 'Niknafs, N., Kim, D., Kim, R., et al. (2013). MuPIT interactive: webserver for mapping variant positions to annotated, interactive 3D structures. Human genetics, 132(11), 1235-1243.' email: '' name: Johns Hopkins - Karchin Lab organization: Johns Hopkins - Karchin Lab website: http://mupit.icm.jhu.edu/MuPIT_Interactive/ groups: [] has_logo: true hidden: false latest_version: 4.3.3 publish_time: 2019-01-30T18:42:26.597314+0000 requires: null size: 5574066 tags: - genes - variants - visualization title: MuPIT type: annotator versions: - 1.0.0 - 4.1.0 - 4.2.1 - 4.2.2 - 4.2.3 - 4.2.4 - 4.2.5 - 4.2.6 - 4.3.0 - 4.3.1 - 4.3.2 - 4.3.3 mutation_assessor: code_size: 22555 commercial_warning: null data_size: 4283258884 data_sources: '3.0': null 3.0.01: null 3.0.02: Release 3 3.0.03: Release 3 3.0.4: Release 3 3.0.5: Release 3 3.0.6: Release 3 3.1.0: Release 3 3.1.1: Release 3 3.1.2: Release 3 3.1.3: Release 3 data_versions: '3.0': '3.0' 3.0.01: '3.0' 3.0.02: '3.0' 3.0.03: '3.0' 3.0.4: '3.0' 3.0.5: '3.0' 3.0.6: '3.0' 3.1.0: 3.1.0 3.1.1: 3.1.0 3.1.2: 3.1.0 3.1.3: 3.1.0 datasource: Release 3 description: Mutation Assessor is a database providing prediction of the functional impact of amino-acid substitutions in proteins developer: citation: Reva, B., Antipin, Y., & Sander, C. (2007). Determinants of protein function revealed by combinatorial entropy optimization. Genome biology, 8(11), R232. email: support@opencravat.org name: Chris Sander organization: Memorial Sloan-Kettering Cancer Center website: http://mutationassessor.org/r3/about.php groups: [] has_logo: true hidden: false latest_version: 3.1.3 publish_time: 2019-01-30T18:42:36.301616+0000 requires: - wgmutation_assessor size: 4283281439 tags: - variant effect prediction - variants title: Mutation Assessor type: annotator versions: - '3.0' - 3.0.01 - 3.0.02 - 3.0.03 - 3.0.4 - 3.0.5 - 3.0.6 - 3.1.0 - 3.1.1 - 3.1.2 - 3.1.3 mutationtaster: code_size: 500823 commercial_warning: null data_size: 12146579460 data_sources: 1.0.0: v4.1a 1.1.0: v4.1a data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: v4.1a description: Evaluates disease-causing potential of sequence alterations developer: citation: "Schwarz, J., R\xF6delsperger, C., Schuelke, M. et al. MutationTaster\ \ evaluates disease-causing potential of sequence alterations. Nat Methods 7,\ \ 575\u2013576 (2010). https://doi.org/10.1038/nmeth0810-575" email: support@opencravat.org name: '' organization: "Department of Neuropediatrics, \u201CCharit\xE9\u2013Universit\xE4\ tsmedizin Berlin\u201D, Berlin, Germany" website: http://www.mutationtaster.org/ChrPos.html groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2024-12-17T20:36:11.180580+0000 requires: - wgmutationtaster size: 12147080283 tags: - variant effect prediction - variants title: MutationTaster type: annotator versions: - 1.0.0 - 1.1.0 mutpanning: code_size: 311973 commercial_warning: null data_size: 75780 data_sources: 1.0.0: v2.0 data_versions: 1.0.0: 1.0.0 datasource: v2.0 description: Discovers new tumor genes in aggregated sequencing data. developer: citation: 'Detlein, Felix, et al. "Identification of cancer driver genes based on nucleotide context." Nature Genetics 52.2 (2020): 208-218.' email: support@opencravat.org name: Broad Institute organization: Broad Institute website: http://www.cancer-genes.org groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-12-17T20:36:11.238513+0000 requires: null size: 387753 tags: - genes - cancer title: Mutpanning type: annotator versions: - 1.0.0 mutpred1: code_size: 400103 commercial_warning: null data_size: 15587162116 data_sources: 1.2.0: null 1.2.1: null 1.2.2: null 1.2.3: v1 1.2.4: v1.2 1.2.5: v1.2 1.2.6: v1.2 1.3.0: v4.1 1.4.0: v4.1 1.5.0: v4.1 data_versions: 1.2.0: 1.2.0 1.2.1: 1.2.0 1.2.2: 1.2.0 1.2.3: 1.2.0 1.2.4: 1.2.0 1.2.5: 1.2.0 1.2.6: 1.2.0 1.3.0: 1.3.0 1.4.0: 1.4.0 1.5.0: 1.4.0 datasource: v4.1 description: MutPred is a random forest model for the prediction of pathogenic missense variants and automated inference of molecular mechanisms of disease. developer: citation: 'Li B, Krishnan VG, Mort ME, Xin F, Kamati KK, Cooper DN, Mooney SD, Radivojac P. Automated inference of molecular mechanisms of disease from amino acid substitutions. Bioinformatics (2009) 25(21): 2744-2750.' email: vpejaver@uw.edu name: Vikas Pejaver organization: University of Washington website: http://mutpred1.mutdb.org/ groups: [] has_logo: true hidden: false latest_version: 1.5.0 publish_time: 2020-10-29T20:22:01.193992+0000 requires: - wgmutpred1 size: 15587562219 tags: - variant effect prediction - variants title: MutPred type: annotator versions: - 1.2.0 - 1.2.1 - 1.2.2 - 1.2.3 - 1.2.4 - 1.2.5 - 1.2.6 - 1.3.0 - 1.4.0 - 1.5.0 mutpred_indel: code_size: 404895 commercial_warning: null data_size: 17905113092 data_sources: 1.0.0: v1.0 1.1.0: v1.0 1.1.1: v1.0 data_versions: 1.0.0: 1.0.0 1.1.0: 1.1.0 1.1.1: 1.1.0 datasource: v1.0 description: A web application developed to classify human non-frameshifting indels as pathogenic or benign. In addition, it predicts their impact on over 50 different protein properties and, thus, enables the inference of molecular mechanisms of pathogenicity. developer: citation: 'Pagel, Kymberleigh A., et al. "Pathogenicity and functional impact of non-frameshifting insertion/deletion variation in the human genome." PLoS computational biology 15.6 (2019): e1007112.' email: support@opencravat.org name: Kymberleigh Pagel organization: Indiana University website: http://mutpred2.mutdb.org/mutpredindel/ groups: [] has_logo: true hidden: false latest_version: 1.1.1 publish_time: 2021-01-19T15:45:50.688799+0000 requires: null size: 17905517987 tags: - variant effect prediction - variants title: MutPred-Indel type: annotator versions: - 1.0.0 - 1.1.0 - 1.1.1 ncbigene: code_size: 93045 commercial_warning: null data_size: 71229440 data_sources: 2018.02.21: null 2018.02.211: null 2018.02.213: null 2019.02.006: null 2019.03.23: 2019.03.23 2019.05.13: 2019.03.23 2019.08.02: 2019.03.23 2022.08.30: 2022.08.30 2024.02.01: 2024.02.01 2024.03.01: 2024.03.01 2024.04.01: 2024.04.01 2024.05.01: 2024.05.01 2024.08.01: 2024.08.01 2024.09.01: 2024.09.01 2024.12.10: 2024.12.10 2025.02.01: 2025.02.01 2025.03.01: 2025.03.01 2025.04.01: 2025.04.01 2025.05.01: 2025.05.01 2025.06.01: 2025.06.01 2025.07.01: 2025.07.01 data_versions: 2018.02.21: 2018.02.21 2018.02.211: 2018.02.21 2018.02.213: 2018.02.21 2019.02.006: 2019.02.006 2019.03.23: 2019.03.23 2019.05.13: 2019.03.23 2019.08.02: 2019.03.23 2022.08.30: 2022.08.30 2024.02.01: 2024.02.01 2024.03.01: 2024.03.01 2024.04.01: 2024.04.01 2024.05.01: 2024.05.01 2024.08.01: 2024.08.01 2024.09.01: 2024.09.01 2024.12.10: 2024.12.10 2025.02.01: 2025.02.01 2025.03.01: 2025.03.01 2025.04.01: 2025.04.01 2025.05.01: 2025.05.01 2025.06.01: 2025.06.01 2025.07.01: 2025.07.01 datasource: 2025.07.01 description: Gene description from NIH's NCBI Gene Info developer: citation: Wheeler, D. L., Barrett, T., Benson, D. A., Bryant, S. H., et al. (2006). Database resources of the national center for biotechnology information. Nucleic acids research, 35(suppl_1), D5-D12. email: '' name: NIH organization: NIH website: https://www.ncbi.nlm.nih.gov/gene groups: [] has_logo: true hidden: false latest_version: 2025.07.01 publish_time: 2025-07-08T15:12:52.461079+0000 requires: - wgncbigene size: 71322485 tags: - genes - literature title: NCBI Gene type: annotator versions: - 2018.02.21 - 2018.02.211 - 2018.02.213 - 2019.02.006 - 2019.03.23 - 2019.05.13 - 2019.08.02 - 2022.08.30 - 2024.02.01 - 2024.03.01 - 2024.04.01 - 2024.05.01 - 2024.08.01 - 2024.09.01 - 2024.12.10 - 2025.02.01 - 2025.03.01 - 2025.04.01 - 2025.05.01 - 2025.06.01 - 2025.07.01 ncer: code_size: 50843 commercial_warning: null data_size: 14529298432 data_sources: 1.0.0: v2 2022.09.22: 2022.09.22 data_versions: 1.0.0: 1.0.0 2022.09.22: 2022.09.22 datasource: 2022.09.22 description: ncER has a good performance for the identification of deleterious variants in the non-coding genome. ncER can also identify non-coding regions associated with cell viability, an in vitro surrogate of essentiality9, and with regulation of an essential gene. developer: citation: Wells, A., Heckerman, D., Torkamani, A. et al. Ranking of non-coding pathogenic variants and putative essential regions of the human genome. Nat Commun 10, 5241 (2019). https://doi.org/10.1038/s41467-019-13212-3 email: support@opencravat.org name: '' organization: Department of Integrative Structural and Computational Biology, The Scripps Research Institute website: https://github.com/TelentiLab/ncER_datasets groups: [] has_logo: true hidden: false latest_version: 2022.09.22 publish_time: 2024-12-17T20:36:11.311346+0000 requires: null size: 14529349275 tags: - non coding title: 'ncER: non-coding essential regulation' type: annotator versions: - 1.0.0 - 2022.09.22 ncrna: code_size: 72911 commercial_warning: null data_size: 5773839 data_sources: 2014.1.10: null 2014.1.102: hg38 2019.02.006: hg38 2019.05.13: hg38 2019.08.19: hg38 2022.12.12: hg38 data_versions: 2014.1.10: 2014.1.10 2014.1.102: 2014.1.10 2019.02.006: 2014.1.10 2019.05.13: 2019.05.13 2019.08.19: 2019.05.13 2022.12.12: 2019.05.13 datasource: hg38 description: Non-coding RNA from RepeatMasker library developer: citation: Bao, W., Kojima, K. K., & Kohany, O. (2015). Repbase Update, a database of repetitive elements in eukaryotic genomes. Mobile DNA, 6(1), 11. email: '' name: Genetic Information Research Institute organization: Genetic Information Research Institute website: https://www.girinst.org/server/RepBase/index.php groups: [] has_logo: true hidden: false latest_version: 2022.12.12 publish_time: 2019-01-30T20:42:51.131258+0000 requires: - wgncrna size: 5846750 tags: - non coding title: ncRNA type: annotator versions: - 2014.1.10 - 2014.1.102 - 2019.02.006 - 2019.05.13 - 2019.08.19 - 2022.12.12 ndex: code_size: 205130 commercial_warning: For commercial users, contact the source databases and purchase an appropriate license if necessary. Screen reader support enabled. data_size: 590848 data_sources: 4.0.0: null 4.0.10: v2 4.0.11: v2 4.0.2: null 4.0.3: v2 4.0.4: v2 4.0.5: v2 4.0.6: v2 4.0.7: v2 4.0.9: v2 data_versions: 4.0.0: 4.0.0 4.0.10: 4.0.0 4.0.11: 4.0.0 4.0.2: 4.0.0 4.0.3: 4.0.0 4.0.4: 4.0.0 4.0.5: 4.0.0 4.0.6: 4.0.0 4.0.7: 4.0.0 4.0.9: 4.0.0 datasource: v2 description: Network Data Exchange developer: citation: Pratt, D., Chen, J., Welker, D., et al. (2015). NDEx, the network data exchange. Cell systems, 1(4), 302-305. email: '' name: The Cytoscape Consortium organization: The Cytoscape Consortium website: http://home.ndexbio.org/index/ groups: - ndex_group has_logo: true hidden: false latest_version: 4.0.11 publish_time: 2019-01-30T01:56:40.452873+0000 requires: - wgndex - ndex_group - wgndexsummary size: 795978 tags: - genes - visualization title: NDEx NCI Cancer Pathways type: annotator versions: - 4.0.0 - 4.0.2 - 4.0.3 - 4.0.4 - 4.0.5 - 4.0.6 - 4.0.7 - 4.0.9 - 4.0.10 - 4.0.11 ndex_chd: code_size: 281595 commercial_warning: For commercial users, contact the source databases and purchase an appropriate license if necessary. Screen reader support enabled. data_size: 114688 data_sources: 1.0.1: v2 1.0.2: v2 data_versions: 1.0.1: 1.0.1 1.0.2: 1.0.2 datasource: v2 description: Network Data Exchange Congenital Heart Disease Pathways developer: citation: Pratt, D., Chen, J., Welker, D., et al. (2015). NDEx, the network data exchange. Cell systems, 1(4), 302-305. email: '' name: The Cytoscape Consortium organization: The Cytoscape Consortium website: http://home.ndexbio.org/index/ groups: - ndex_group has_logo: true hidden: false latest_version: 1.0.2 publish_time: 2020-09-22T21:59:57.515766+0000 requires: - wgndex_chd - ndex_group - wgndex_chdsummary size: 396283 tags: - variants - genes - cancer title: NDEx Congenital Heart Disease type: annotator versions: - 1.0.1 - 1.0.2 ndex_group: code_size: 74778 commercial_warning: null data_size: 0 data_sources: 1.0.0: 2020.08 data_versions: 1.0.0: null datasource: 2020.08 description: NDEx Annotation Modules developer: email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: https://insilico.us.com groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2021-06-24T18:06:33.393808+0000 requires: null size: 74778 tags: - variants - genes title: NDEx type: group versions: - 1.0.0 ndex_signor: code_size: 214699 commercial_warning: For commercial users, contact the source databases and purchase an appropriate license if necessary. Screen reader support enabled. data_size: 102400 data_sources: 1.0.0: v2 1.0.2: v2 data_versions: 1.0.0: 1.0.0 1.0.2: 1.0.0 datasource: v2 description: Network Data Exchange Signor Pathways developer: citation: Pratt, D., Chen, J., Welker, D., et al. (2015). NDEx, the network data exchange. Cell systems, 1(4), 302-305. email: '' name: The Cytoscape Consortium organization: The Cytoscape Consortium website: http://home.ndexbio.org/index/ groups: - ndex_group has_logo: true hidden: false latest_version: 1.0.2 publish_time: 2020-08-18T00:46:34.699489+0000 requires: - wgndex_signor - ndex_group - wgndex_signorsummary size: 317099 tags: - variants - genes - cancer title: NDEx SIGNOR type: annotator versions: - 1.0.0 - 1.0.2 oldcravat-converter: code_size: 9561 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 1.1.1: null 1.1.2: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 1.1.1: null 1.1.2: null datasource: null description: File converter for old architecture cravat input developer: email: kmoad@insilico.us.com itation: '' name: Kyle Moad organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.1.2 publish_time: '2019-01-07T22:43:03.000000' requires: null size: 9561 tags: null title: OldCravat Converter type: converter versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 - 1.1.1 - 1.1.2 omim: code_size: 15467 commercial_warning: null data_size: 10360836 data_sources: 1.0.0: v4.1 1.1.0: v4.1 data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: v4.1 description: Online Mendelian Inheritance in Man. Catalog of human genes and genetic disorders and traits. developer: citation: 'Amberger JS, Bocchini CA, Scott AF, Hamosh A. OMIM.org: leveraging knowledge across phenotype-gene relationships. Nucleic Acids Res. 2019 Jan 8;47(D1):D1038-D1043. doi:10.1093/nar/gky1151. PMID: 30445645.' email: support@opencravat.org name: Johns Hopkins University organization: Johns Hopkins University website: https://omim.org/ groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2020-08-21T19:10:57.862193+0000 requires: null size: 10376303 tags: - variants - clinical relevance title: OMIM type: annotator versions: - 1.0.0 - 1.1.0 oncokb: code_size: 246432 commercial_warning: For commercial use, visit https://www.oncokb.org/account/register. data_size: 0 data_sources: 1.1.1: 11.29.21 1.1.2: 11.29.21 1.1.3: APIv1 data_versions: 1.1.1: null 1.1.2: null 1.1.3: null datasource: APIv1 description: '*Local Installation Use Only* OncoKB is a precision oncology knowledge base that annotates the biological consequences and clinical implications (therapeutic, diagnostic, and prognostic) of genetic variants in cancer.' developer: citation: 'Chakravarty, Debyani, et al. "OncoKB: a precision oncology knowledge base." JCO precision oncology 1 (2017): 1-16.' email: rkim@oakbioinformatics.com name: Memorial Sloan Cancer Center organization: Memorial Sloan Cancer Center website: https://www.oncokb.org/ groups: [] has_logo: true hidden: false latest_version: 1.1.3 publish_time: 2025-01-20T19:50:33.449090+0000 requires: - wgoncokb size: 246432 tags: - cancer title: OncoKB type: annotator versions: - 1.1.1 - 1.1.2 - 1.1.3 pandasreporter: code_size: 197548 commercial_warning: null data_size: 0 data_sources: 1.1.0: null 1.2.0: null data_versions: 1.1.0: null 1.2.0: null datasource: null description: Python pandas DataFrame reporter developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2021-02-18T19:52:45.484056+0000 requires: null size: 197548 tags: - input/output title: pandas Reporter type: reporter versions: - 1.1.0 - 1.2.0 pangalodb: code_size: 398632 commercial_warning: null data_size: 940036 data_sources: 1.0.0: 2020.03.27 data_versions: 1.0.0: 1.0.0 datasource: 2020.03.27 description: PanglaoDB is a single cell gene expression resource for the scientific community. The goal of this database is to provide exploration of single cell RNA sequencing experiments. developer: citation: "Oscar Franz\xE9n, Li-Ming Gan, Johan L M Bj\xF6rkegren, PanglaoDB:\ \ a web server for exploration of mouse and human single-cell RNA sequencing\ \ data, Database, Volume 2019, 2019, baz046, https://doi.org/10.1093/database/baz046" email: support@opencravat.org name: Oscar Franzen organization: Integrated Cardio Metabolic Centre at Karolinska Institutet. website: https://panglaodb.se/markers.html?cell_type=%27Smooth%20muscle%20cells%27 groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-12-17T20:36:11.392663+0000 requires: - wgpangalodb size: 1338668 tags: - genes title: PangaloDB type: annotator versions: - 1.0.0 pathogenic: code_size: 608072 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: Package that identifies disease related variants. developer: citation: '' email: support@opencravat.org name: OpenCRAVAT Team organization: KarchinLab website: https://opencravat.org groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2023-03-13T13:23:35.766907+0000 requires: - clinvar - clinvar_acmg - denovo - gwas_catalog - clingen - tsvreporter size: 608072 tags: null title: Pathogenic Variant Package type: package versions: - 1.0.0 pharmgkb: code_size: 250658 commercial_warning: null data_size: 3650280 data_sources: 1.0.0: null 1.1.0: null 1.1.1: null 2.0.0: '2021-01-14' 2.1.0: '2021-03-03' 2.2.0: '2021-03-03' 2.3.0: '2021-04-01' 2.3.1: '2021-05-01' 2.3.2: '2021-06-01' 2.3.3: '2021-08-01' 2.3.4: '2021-09-01' 2.3.5: '2021-10-01' 2.3.6: '2022-11-01' 2.3.7: '2023-01-01' 2.3.8: '2023-02-01' 2.3.9: '2024-02-01' 2.4.0: '2024-03-01' 2.4.1: '2024-04-01' 2.4.2: '2024-05-01' 2.4.3: '2024-08-01' 2024.12.10: 2024.12.10 2025.02.01: 2025.02.01 2025.03.01: 2025.03.01 2025.04.01: 2025.04.01 2025.05.01: 2025.05.01 2025.06.01: 2025.06.01 2025.06.25: 2025.06.01 2025.07.01: 2025.07.01 data_versions: 1.0.0: 1.0.0 1.1.0: 1.1.0 1.1.1: 1.1.0 2.0.0: 2.0.0 2.1.0: 2.1.0 2.2.0: 2.2.0 2.3.0: 2.3.0 2.3.1: 2.3.1 2.3.2: 2.3.2 2.3.3: 2.3.3 2.3.4: 2.3.4 2.3.5: 2.3.5 2.3.6: 2.3.6 2.3.7: 2.3.7 2.3.8: 2.3.8 2.3.9: 2.3.9 2.4.0: 2.4.0 2.4.1: 2.4.1 2.4.2: 2.4.2 2.4.3: 2.4.3 2024.12.10: 2024.12.10 2025.02.01: 2025.02.01 2025.03.01: 2025.03.01 2025.04.01: 2025.04.01 2025.05.01: 2025.05.01 2025.06.01: 2025.06.01 2025.06.25: 2025.06.01 2025.07.01: 2025.07.01 datasource: 2025.07.01 description: Clinically actionable gene-drug associations and genotype-phenotype relationships developer: citation: 'M. Whirl-Carrillo, E.M. McDonagh, J. M. Hebert, L. Gong, K. Sangkuhl, C.F. Thorn, R.B. Altman and T.E. Klein. "Pharmacogenomics Knowledge for Personalized Medicine" Clinical Pharmacology & Therapeutics (2012) 92(4): 414-417' email: feedback@pharmgkb.org name: Teri E. Klein organization: Shriram Center for Bioengineering and Chemical Engineering website: https://www.pharmgkb.org/ groups: [] has_logo: true hidden: false latest_version: 2025.07.01 publish_time: 2025-07-08T15:12:52.741349+0000 requires: - wgpharmgkb>=2.0.0 size: 3900938 tags: - clinical relevance - literature - variants title: PharmGKB type: annotator versions: - 1.0.0 - 1.1.0 - 1.1.1 - 2.0.0 - 2.1.0 - 2.2.0 - 2.3.0 - 2.3.1 - 2.3.2 - 2.3.3 - 2.3.4 - 2.3.5 - 2.3.6 - 2.3.7 - 2.3.8 - 2.3.9 - 2.4.0 - 2.4.1 - 2.4.2 - 2.4.3 - 2024.12.10 - 2025.02.01 - 2025.03.01 - 2025.04.01 - 2025.05.01 - 2025.06.01 - 2025.06.25 - 2025.07.01 phastcons: code_size: 119644 commercial_warning: null data_size: 5986715652 data_sources: 3.5.0: null 3.5.01: null 3.5.02: dbNSFP v4.0b1 3.5.03: dbNSFP v4.0b1 3.5.04: dbNSFP v4.0b1 3.5.5: dbNSFP v4.0b1 3.5.6: dbNSFP v4.0b1 3.5.7: dbNSFP v4.0b1 3.5.8: dbNSFP v4.0b1 3.5.9: dbNSFP v4.0b1 3.6.0: dbNSFP v4.5a data_versions: 3.5.0: 3.5.0 3.5.01: 3.5.0 3.5.02: 3.5.0 3.5.03: 3.5.0 3.5.04: 3.5.04 3.5.5: 3.5.04 3.5.6: 3.5.04 3.5.7: 3.5.04 3.5.8: 3.5.04 3.5.9: 3.5.04 3.6.0: 3.6.0 datasource: dbNSFP v4.5a description: A database of compressed phastCons conservation scores. developer: citation: Pollard, K. S., Hubisz, M. J., Rosenbloom, K. R., & Siepel, A. (2010). Detection of nonneutral substitution rates on mammalian phylogenies. Genome research, 20(1), 110-121. email: support@opencravat.org name: UCSC organization: University of California Santa Cruz Genomics Institute website: https://sites.google.com/site/jpopgen/dbNSFP groups: [] has_logo: true hidden: false latest_version: 3.6.0 publish_time: 2024-12-17T20:36:12.127979+0000 requires: - wgphastcons>=1.2.0 size: 5986835296 tags: - variants - evolution title: Phast Cons type: annotator versions: - 3.5.0 - 3.5.01 - 3.5.02 - 3.5.03 - 3.5.04 - 3.5.5 - 3.5.6 - 3.5.7 - 3.5.8 - 3.5.9 - 3.6.0 phdsnpg: code_size: 23603 commercial_warning: null data_size: 5253156864 data_sources: 0.0.2: null 0.0.4: null 0.0.5: dbNSFP v4.0b1 0.0.6: dbNSFP v4.0b1 0.0.7: dbNSFP v4.0b1 0.0.8: dbNSFP v4.0b1 0.0.9: dbNSFP v4.0b1 0.1.0: dbNSFP v4.0b1 data_versions: 0.0.2: 0.0.2 0.0.4: 0.0.2 0.0.5: 0.0.2 0.0.6: 0.0.2 0.0.7: 0.0.2 0.0.8: 0.0.2 0.0.9: 0.0.2 0.1.0: 0.0.2 datasource: dbNSFP v4.0b1 description: A binary classifier for predicting pathogenic variants in coding and non-coding regions. developer: citation: 'Capriotti, E., & Fariselli, P. (2017). PhD-SNPg: a webserver and lightweight tool for scoring single nucleotide variants. Nucleic acids research, 45(W1), W247-W252.' email: emidio.capriotti@unibo.it name: Emidio Capriotti organization: University of Bologna website: http://snps.biofold.org/phd-snpg/index.html groups: [] has_logo: true hidden: false latest_version: 0.1.0 publish_time: 2019-01-30T18:44:04.627754+0000 requires: - wgphdsnpg size: 5253180467 tags: - variant effect prediction - variants title: PhD-SNPg type: annotator versions: - 0.0.2 - 0.0.4 - 0.0.5 - 0.0.6 - 0.0.7 - 0.0.8 - 0.0.9 - 0.1.0 phi: code_size: 17663 commercial_warning: null data_size: 698372 data_sources: 3.5.0: 3.5.0 3.5.1: dbNSFP v4.0b1 3.5.2: dbNSFP v4.0b1 3.5.3: dbNSFP v4.0b1 3.5.4: dbNSFP v4.0b1 3.6.0: dbNSFP v4.0b1 3.6.1: dbNSFP v4.0b1 data_versions: 3.5.0: 3.5.0 3.5.1: 3.5.0 3.5.2: 3.5.0 3.5.3: 3.5.0 3.5.4: 3.5.0 3.6.0: 3.6.0 3.6.1: 3.6.0 datasource: dbNSFP v4.0b1 description: Providing probabilities for gene-based haploinsufficiency developer: citation: Huang, N., Lee, I., Marcotte, E. M., & Hurles, M. E. (2010). Characterising and predicting haploinsufficiency in the human genome. PLoS genetics, 6(10), e1001154. email: support@opencravat.org name: Ni Huang, Insuk Lee, Edward M. Marcotte, Matthew E. Hurles organization: Wellcome Trust Sanger Institute website: https://doi.org/10.1371/journal.pgen.1001154 groups: [] has_logo: true hidden: false latest_version: 3.6.1 publish_time: 2019-01-30T18:44:14.269915+0000 requires: null size: 716035 tags: - genes title: p(HI) type: annotator versions: - 3.5.0 - 3.5.1 - 3.5.2 - 3.5.3 - 3.5.4 - 3.6.0 - 3.6.1 phylop: code_size: 238282 commercial_warning: null data_size: 6421039108 data_sources: 3.5.0: null 3.5.01: null 3.5.02: null 3.5.03: hg38 3.5.04: hg38 3.5.05: hg38 3.5.10: dbNSFP v4.0b1 3.5.6: dbNSFP v4.0b1 3.5.7: dbNSFP v4.0b1 3.5.8: dbNSFP v4.0b1 3.5.9: dbNSFP v4.0b1 3.6.0: dbNSFP v4.5a 3.7.0: dbNSFP v4.5a data_versions: 3.5.0: 3.5.0 3.5.01: 3.5.0 3.5.02: 3.5.0 3.5.03: 3.5.0 3.5.04: 3.5.0 3.5.05: 3.5.05 3.5.10: 3.5.05 3.5.6: 3.5.05 3.5.7: 3.5.05 3.5.8: 3.5.05 3.5.9: 3.5.05 3.6.0: 3.6.0 3.7.0: 3.6.0 datasource: dbNSFP v4.5a description: A database providing conservation scoring by phylogenetic p-values developer: citation: Pollard, K. S., Hubisz, M. J., Rosenbloom, K. R., & Siepel, A. (2010). Detection of nonneutral substitution rates on mammalian phylogenies. Genome research, 20(1), 110-121. email: support@opencravat.org name: UCSC organization: University of California Santa Cruz Genomics Institute website: https://sites.google.com/site/jpopgen/dbNSFP groups: [] has_logo: true hidden: false latest_version: 3.7.0 publish_time: 2024-03-25T13:13:29.663866+0000 requires: - wgphylop>=1.2.0 size: 6421277390 tags: - variants - variant effect prediction - evolution title: PhyloP type: annotator versions: - 3.5.0 - 3.5.01 - 3.5.02 - 3.5.03 - 3.5.04 - 3.5.05 - 3.5.6 - 3.5.7 - 3.5.8 - 3.5.9 - 3.5.10 - 3.6.0 - 3.7.0 polyphen2: code_size: 32286 commercial_warning: null data_size: 8269815808 data_sources: 1.0.0: '2' 1.1.0: v4.1 2022.09.19: 2022.09.19 2022.09.27: 2022.09.27 2022.10.13: 2022.10.13 2024.01.12: 2022.10.13 data_versions: 1.0.0: 1.0.0 1.1.0: 1.1.0 2022.09.19: 1.1.0 2022.09.27: 2022.09.27 2022.10.13: 2022.09.27 2024.01.12: 2022.09.27 datasource: 2022.10.13 description: PolyPhen-2 (Polymorphism Phenotyping v2) is a tool which predicts possible impact of an amino acid substitution on the structure and function of a human protein using straightforward physical and comparative considerations developer: citation: Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, Kondrashov AS, Sunyaev SR. Nat Methods 7(4):248-249 (2010). email: iadzhubey@rics.bwh.harvard.edu name: Ivan A Adzhubei organization: Brigham and Women's Hospital website: http://genetics.bwh.harvard.edu/pph2/ groups: [] has_logo: true hidden: false latest_version: 2024.01.12 publish_time: 2023-06-22T17:54:08.385611+0000 requires: null size: 8269848094 tags: - variant effect prediction - variants title: PolyPhen-2 type: annotator versions: - 1.0.0 - 1.1.0 - 2022.09.19 - 2022.09.27 - 2022.10.13 - 2024.01.12 prec: code_size: 22064 commercial_warning: null data_size: 575492 data_sources: 3.5.0: 3.5.0 3.5.1: 3.5.0 3.5.2: dbNSFP v4.0b1 3.5.3: dbNSFP v4.0b1 3.5.4: dbNSFP v4.0b1 3.5.5: dbNSFP v4.0b1 3.5.6: dbNSFP v4.0b1 3.5.7: dbNSFP v4.0b1 3.6.0: dbNSFP v4.0b1 data_versions: 3.5.0: 3.5.0 3.5.1: 3.5.0 3.5.2: 3.5.0 3.5.3: 3.5.0 3.5.4: 3.5.0 3.5.5: 3.5.0 3.5.6: 3.5.0 3.5.7: 3.5.0 3.6.0: 3.6.0 datasource: dbNSFP v4.0b1 description: Providing probabilities for LoF alleles developer: citation: MacArthur, D. G., Balasubramanian, S., Frankish, A., et al. (2012). A systematic survey of loss-of-function variants in human protein-coding genes. Science, 335(6070), 823-828. email: support@opencravat.org name: Daniel G. MacArthur organization: Wellcome Trust Sanger Institute website: https://doi.org/10.1126/science.1215040 groups: [] has_logo: true hidden: false latest_version: 3.6.0 publish_time: '2019-01-28T21:42:44.000000' requires: - wgprec size: 597556 tags: - genes title: P(rec) type: annotator versions: - 3.5.0 - 3.5.1 - 3.5.2 - 3.5.3 - 3.5.4 - 3.5.5 - 3.5.6 - 3.5.7 - 3.6.0 primateai: code_size: 139354 commercial_warning: null data_size: 3580977152 data_sources: 1.0.0: dbNSFPv4.7a data_versions: 1.0.0: 1.0.0 datasource: dbNSFPv4.7a description: Deep residual neural network for classifying the pathogenicity of missense mutations developer: citation: "Sundaram, L., Gao, H., Padigepati, S.R. et al. Predicting the clinical\ \ impact of human mutation with deep neural networks. Nat Genet 50, 1161\u2013\ 1170 (2018). https://doi.org/10.1038/s41588-018-0167-z" email: support@opencravat.org name: '' organization: Illumina Artificial Intelligence Laboratory, Illumina Inc, San Diego, CA, USA website: https://github.com/Illumina/PrimateAI groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2025-04-18T18:17:29.665031+0000 requires: - wgprimateai size: 3581116506 tags: - variants - variant effect prediction - clinical relevance title: PrimateAI type: annotator versions: - 1.0.0 provean: code_size: 90438 commercial_warning: null data_size: 12534163460 data_sources: 1.0.0: v4.1a 1.1.0: v4.1a data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 datasource: v4.1a description: A tool to predict the functional effect of amino acid substitutions and indels. developer: citation: 'Choi Y, Chan AP (2015) PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels. Bioinformatics 31(16): 2745-2747.' email: support@cravat.us name: Yongwook Choi, Agnes Chan organization: J. Craig Venter Institute (JCVI) website: http://provean.jcvi.org/index.php groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2025-04-23T19:30:50.773392+0000 requires: - wgprovean size: 12534253898 tags: - variant effect prediction title: 'PROVEAN: Protein Variant Effect Analyzer' type: annotator versions: - 1.0.0 - 1.1.0 pseudogene: code_size: 44116 commercial_warning: null data_size: 1148955 data_sources: 1.0.0: null 27.0.0: null 27.0.1: null 27.0.2: null 27.0.3: null 27.0.4: hg38 27.0.5: hg38 27.0.6: hg38 28.0.1: hg38 42.0.1: hg38 45.0.0: hg38 46.0.0: hg38 47.0.0: hg38 48.0.0: hg38 data_versions: 1.0.0: 1.0.0 27.0.0: 1.0.0 27.0.1: 1.0.0 27.0.2: 1.0.0 27.0.3: 1.0.0 27.0.4: 1.0.0 27.0.5: 1.0.0 27.0.6: 1.0.0 28.0.1: 28.0.1 42.0.1: 42.0.1 45.0.0: 45.0.0 46.0.0: 46.0.0 47.0.0: 47.0.0 48.0.0: 48.0.0 datasource: hg38 description: Pseudogenes from UCSC hg38 wgEncodeGencodePseudoGeneV46 developer: citation: 'Harrow, J., Frankish, A., Gonzalez, J. M., Tapanari, E., Diekhans, M., Kokocinski, F., ... & Barnes, I. (2012). GENCODE: the reference human genome annotation for The ENCODE Project. Genome research, 22(9), 1760-1774.' email: '' name: UCSC organization: UCSC website: https://www.gencodegenes.org/ groups: [] has_logo: true hidden: false latest_version: 48.0.0 publish_time: 2019-01-30T18:44:48.081851+0000 requires: - wgpseudogene size: 1193071 tags: - non coding title: Pseudogene type: annotator versions: - 1.0.0 - 27.0.0 - 27.0.1 - 27.0.2 - 27.0.3 - 27.0.4 - 27.0.5 - 27.0.6 - 28.0.1 - 42.0.1 - 45.0.0 - 46.0.0 - 47.0.0 - 48.0.0 pubmed: code_size: 47739 commercial_warning: null data_size: 933888 data_sources: 1.0.0: null 1.1.0: null 1.1.1: null 1.1.2: null 1.1.3: null 1.1.4: null 1.1.5: null data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 1.1.1: 1.0.0 1.1.2: 1.0.0 1.1.3: 1.0.0 1.1.4: 1.0.0 1.1.5: 1.0.0 datasource: null description: PubMed articles related to a particular gene developer: citation: '' email: pubmedcentral@ncbi.nlm.nih.gov name: NCBI organization: NCBI website: https://www.ncbi.nlm.nih.gov/pubmed groups: [] has_logo: true hidden: false latest_version: 1.1.5 publish_time: '2018-09-27T17:48:28.000000' requires: null size: 981627 tags: - literature title: PubMed type: annotator versions: - 1.0.0 - 1.1.0 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.1.5 rare_coding: code_size: 469462 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: Package that identifies rare coding variants developer: citation: '' email: support@opencravat.org name: OpenCRAVAT Team organization: KarchinLab website: https://opencravat.org groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2023-03-13T13:26:08.887996+0000 requires: - dbsnp - gnomad3 - go - ncbigene - tsvreporter size: 469462 tags: null title: Rare Coding Package type: package versions: - 1.0.0 rdatareporter: code_size: 17935 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.1.0: null 1.2.0: null data_versions: 1.0.0: null 1.0.1: null 1.1.0: null 1.2.0: null datasource: null description: RData file is generated from a result database. developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-11-10T17:20:20.547143+0000 requires: null size: 17935 tags: - input/output title: RData Reporter type: reporter versions: - 1.0.0 - 1.0.1 - 1.1.0 - 1.2.0 regeneron: code_size: 506154 commercial_warning: null data_size: 3028418560 data_sources: 1.0.0: null data_versions: 1.0.0: 1.0.0 datasource: null description: Allele counts and frequencies from the Regeneron Million Exomes dataset. developer: citation: "Sun, K. Y. et al. A deep catalogue of protein-coding variation in 983,578\ \ individuals. Nature 631, 583\u2013592 (2024)." email: mdawood@bcm.edu name: Moez Dawood organization: Regeneron Genetics Center and Baylor College of Medicine Human Genome Sequencing Center website: https://rgc-research.regeneron.com/me/home groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2025-04-14T19:44:44.028411+0000 requires: null size: 3028924714 tags: - variants - allele frequency title: Regeneron type: annotator versions: - 1.0.0 regulomedb: code_size: 75972 commercial_warning: null data_size: 1067202564 data_sources: 1.0.0: v2.0 1.0.1: v2.0 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 datasource: v2.0 description: Identifies DNA features and regulatory elements in non-coding regions of the human genome. developer: citation: 'Boyle AP, Hong EL, Hariharan M, Cheng Y, Schaub MA, Kasowski M, Karczewski KJ, Park J, Hitz BC, Weng S, Cherry JM, Snyder M. Annotation of functional variation in personal genomes usingRegulomeDB. Genome Research 2012, 22(9):1790-1797. PMID: 22955989.' email: support@opencravat.org name: '' organization: Stanford University website: https://www.regulomedb.org/ groups: [] has_logo: true hidden: false latest_version: 1.0.1 publish_time: 2021-03-31T15:14:10.837161+0000 requires: null size: 1067278536 tags: - non coding title: RegulomeDB type: annotator versions: - 1.0.0 - 1.0.1 repeat: code_size: 69574 commercial_warning: null data_size: 366328832 data_sources: 2014.1.10: null 2014.1.101: null 2014.1.102: null 2014.1.104: hg38 2019.05.13: hg38 2019.08.02: hg38 2019.08.22: hg38 2019.2.060: hg38 2020.10.16: hg38 data_versions: 2014.1.10: 2014.1.10 2014.1.101: 2014.1.10 2014.1.102: 2014.1.10 2014.1.104: 2014.1.10 2019.05.13: 2014.1.10 2019.08.02: 2014.1.10 2019.08.22: 2014.1.10 2019.2.060: 2014.1.10 2020.10.16: 2014.1.10 datasource: hg38 description: Repeating elements from RepeatMasker and Simple Repeat tracks of UCSC hg38 database. UCSC Genome Browser Tracks rmsk and simpleRepeat were used to obtain Low complexity, SINE, LINE, LTR, Simple Repeat, and Satellite data and they were combined. developer: citation: 'Haeussler, M., Zweig, A. S., Tyner, C., et al. (2018). The UCSC Genome Browser database: 2019 update. Nucleic acids research, 47(D1), D853-D858.' email: '' name: null organization: UCSC website: http://genome.ucsc.edu groups: [] has_logo: true hidden: false latest_version: 2020.10.16 publish_time: 2019-01-30T18:45:06.202135+0000 requires: null size: 366398406 tags: - non coding title: Repeat Sequences type: annotator versions: - 2014.1.10 - 2014.1.101 - 2014.1.102 - 2014.1.104 - 2019.2.060 - 2019.05.13 - 2019.08.02 - 2019.08.22 - 2020.10.16 revel: code_size: 127256 commercial_warning: For commercial use, contact xmliu.uth@gmail.com data_size: 6989649924 data_sources: 2016.06.03: 2016.06.03 2016.06.04: 2016.06.03 2019.02.06: 2016.06.03 2019.03.20: 2016.06.03 2019.03.27: 2019.03.27 2019.05.13: '2017-06-21' 2020.12.02: v4.1a 2022.11.29: v4.3a 2024.07.30: v4.3a data_versions: 2016.06.03: 2016.06.03 2016.06.04: 2016.06.03 2019.02.06: 2016.06.03 2019.03.20: 2016.06.03 2019.03.27: 2019.03.27 2019.05.13: 2019.03.27 2020.12.02: 2020.12.02 2022.11.29: 2022.11.29 2024.07.30: 2022.11.29 datasource: v4.3a description: Rare Exome Variant Ensemble Learner developer: citation: 'Ioannidis, N. M., Rothstein, J. H., Pejaver, V., et al. (2016). REVEL: an ensemble method for predicting the pathogenicity of rare missense variants. The American Journal of Human Genetics, 99(4), 877-885.' email: joseph.rothstein@mssm.edu name: Joe Rothstein organization: Icahn School of Medicine at Mount Sinai website: https://sites.google.com/site/revelgenomics/ groups: [] has_logo: true hidden: false latest_version: 2024.07.30 publish_time: 2023-06-22T17:54:08.483014+0000 requires: - wgrevel size: 6989777180 tags: - variant effect prediction - variants - clinical relevance title: REVEL type: annotator versions: - 2016.06.03 - 2016.06.04 - 2019.02.06 - 2019.03.20 - 2019.03.27 - 2019.05.13 - 2020.12.02 - 2022.11.29 - 2024.07.30 rvis: code_size: 16266 commercial_warning: null data_size: 1353732 data_sources: 3.0.0: null 3.0.01: null 3.0.02: null 3.0.03: null 3.0.04: v3 3.0.05: v3 3.0.6: v3 3.0.7: v3 3.0.8: v3 3.1.0: v3 data_versions: 3.0.0: 3.0.0 3.0.01: 3.0.0 3.0.02: 3.0.0 3.0.03: 3.0.0 3.0.04: 3.0.0 3.0.05: 3.0.0 3.0.6: 3.0.0 3.0.7: 3.0.0 3.0.8: 3.0.0 3.1.0: 3.1.0 datasource: v3 description: Residual variation intolerance scoring developer: citation: Petrovski, S., Wang, Q., Heinzen, E. L., Allen, A. S., & Goldstein, D. B. (2013). Genic intolerance to functional variation and the interpretation of personal genomes. PLoS genetics, 9(8), e1003709. email: support@opencravat.org name: "Slav\xE9 Petrovski, Quanli Wang, Erin L. Heinzen, Andrew S. Allen, David\ \ B. Goldstein" organization: Center for Human Genome Variation, Duke University website: https://doi.org/10.1371/journal.pgen.1003709 groups: [] has_logo: true hidden: false latest_version: 3.1.0 publish_time: 2019-01-30T18:45:23.421954+0000 requires: - wgrvis size: 1369998 tags: - genes title: RVIS type: annotator versions: - 3.0.0 - 3.0.01 - 3.0.02 - 3.0.03 - 3.0.04 - 3.0.05 - 3.0.6 - 3.0.7 - 3.0.8 - 3.1.0 segway: code_size: 164238 commercial_warning: null data_size: 8093696 data_sources: 1.0.0: null 1.2.0: null 1.2.1: null data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 1.2.1: 1.0.0 datasource: null description: Chromatin state activity scores developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.1 publish_time: 2020-09-12T20:08:49.525614+0000 requires: - segway_group size: 8257934 tags: - variants - non coding title: Segway type: annotator versions: - 1.0.0 - 1.2.0 - 1.2.1 segway_adrenal: code_size: 11669 commercial_warning: null data_size: 318869504 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Adrenal tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:09:37.106540+0000 requires: - segway_group size: 318881173 tags: - non coding title: Segway Adrenal type: annotator versions: - 1.0.0 - 1.2.0 segway_blood: code_size: 18175 commercial_warning: null data_size: 10196074496 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Blood tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:10:24.447585+0000 requires: - segway_group size: 10196092671 tags: - non coding title: Segway Blood type: annotator versions: - 1.0.0 - 1.2.0 segway_brain: code_size: 20613 commercial_warning: null data_size: 4480552960 data_sources: 1.0.0: 2019.09.01 1.1.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.1.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Brain tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:11:11.639143+0000 requires: - segway_group size: 4480573573 tags: - non coding title: Segway Brain type: annotator versions: - 1.0.0 - 1.1.0 - 1.2.0 segway_breast: code_size: 11957 commercial_warning: null data_size: 691527680 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Breast tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:11:58.740914+0000 requires: - segway_group size: 691539637 tags: - non coding title: Segway Breast type: annotator versions: - 1.0.0 - 1.2.0 segway_esc: code_size: 12787 commercial_warning: null data_size: 1872506880 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Esc tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:12:46.087067+0000 requires: - segway_group size: 1872519667 tags: - non coding title: Segway Esc type: annotator versions: - 1.0.0 - 1.2.0 segway_esc_derived: code_size: 14605 commercial_warning: null data_size: 5715992576 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Esc Derived tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:13:33.407910+0000 requires: - segway_group size: 5716007181 tags: - non coding title: Segway Esc Derived type: annotator versions: - 1.0.0 - 1.2.0 segway_fat: code_size: 12045 commercial_warning: null data_size: 1032069120 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Fat tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:14:20.790696+0000 requires: - segway_group size: 1032081165 tags: - non coding title: Segway Fat type: annotator versions: - 1.0.0 - 1.2.0 segway_gi_colon: code_size: 12223 commercial_warning: null data_size: 1098141696 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for GI Colon tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:15:08.176627+0000 requires: - segway_group size: 1098153919 tags: - non coding title: Segway GI Colon type: annotator versions: - 1.0.0 - 1.2.0 segway_gi_duodenum: code_size: 11974 commercial_warning: null data_size: 908914688 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for GI Duodenum tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:15:55.361222+0000 requires: - segway_group size: 908926662 tags: - non coding title: Segway GI Duodenum type: annotator versions: - 1.0.0 - 1.2.0 segway_gi_intestine: code_size: 11988 commercial_warning: null data_size: 777023488 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for GI Intestine tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:16:42.646577+0000 requires: - segway_group size: 777035476 tags: - non coding title: Segway GI Intestine type: annotator versions: - 1.0.0 - 1.2.0 segway_gi_rectum: code_size: 12287 commercial_warning: null data_size: 1451003904 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for GI Rectum tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:17:30.113048+0000 requires: - segway_group size: 1451016191 tags: - non coding title: Segway GI Rectum type: annotator versions: - 1.0.0 - 1.2.0 segway_gi_stomach: code_size: 12493 commercial_warning: null data_size: 1518788608 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for GI Stomach tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:18:17.380751+0000 requires: - segway_group size: 1518801101 tags: - non coding title: Segway GI Stomach type: annotator versions: - 1.0.0 - 1.2.0 segway_group: code_size: 6882 commercial_warning: null data_size: 0 data_sources: 1.0.0: 2019.09 data_versions: 1.0.0: null datasource: 2019.09 description: Chromatin state annotations from Segway developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2020-09-12T20:38:14.401354+0000 requires: null size: 6882 tags: - non coding title: Segway type: group versions: - 1.0.0 segway_heart: code_size: 12473 commercial_warning: null data_size: 1492787200 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Heart tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:19:05.928121+0000 requires: - segway_group size: 1492799673 tags: - non coding title: Segway Heart type: annotator versions: - 1.0.0 - 1.2.0 segway_ipsc: code_size: 12807 commercial_warning: null data_size: 2085855232 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Ipsc tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:19:53.460029+0000 requires: - segway_group size: 2085868039 tags: - non coding title: Segway Ipsc type: annotator versions: - 1.0.0 - 1.2.0 segway_kidney: code_size: 11649 commercial_warning: null data_size: 493993984 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Kidney tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:20:40.781153+0000 requires: - segway_group size: 494005633 tags: - non coding title: Segway Kidney type: annotator versions: - 1.0.0 - 1.2.0 segway_liver: code_size: 11637 commercial_warning: null data_size: 367927296 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Liver tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:21:27.900970+0000 requires: - segway_group size: 367938933 tags: - non coding title: Segway Liver type: annotator versions: - 1.0.0 - 1.2.0 segway_lung: code_size: 11633 commercial_warning: null data_size: 368173056 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Lung tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:22:15.165440+0000 requires: - segway_group size: 368184689 tags: - non coding title: Segway Lung type: annotator versions: - 1.0.0 - 1.2.0 segway_muscle: code_size: 12269 commercial_warning: null data_size: 1135779840 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Muscle tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:23:02.628756+0000 requires: - segway_group size: 1135792109 tags: - non coding title: Segway Muscle type: annotator versions: - 1.0.0 - 1.2.0 segway_muscle_leg: code_size: 11672 commercial_warning: null data_size: 297504768 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Muscle Leg tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:23:50.095197+0000 requires: - segway_group size: 297516440 tags: - non coding title: Segway Muscle Leg type: annotator versions: - 1.0.0 - 1.2.0 segway_ovary: code_size: 11621 commercial_warning: null data_size: 342245376 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Ovary tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:24:37.436427+0000 requires: - segway_group size: 342256997 tags: - non coding title: Segway Ovary type: annotator versions: - 1.0.0 - 1.2.0 segway_placenta: code_size: 11942 commercial_warning: null data_size: 822734848 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Placenta tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:25:24.640069+0000 requires: - segway_group size: 822746790 tags: - non coding title: Segway Placenta type: annotator versions: - 1.0.0 - 1.2.0 segway_skin: code_size: 13638 commercial_warning: null data_size: 2971197440 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Skin tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:26:12.111781+0000 requires: - segway_group size: 2971211078 tags: - non coding title: Segway Skin type: annotator versions: - 1.0.0 - 1.2.0 segway_stromal_connective: code_size: 12289 commercial_warning: null data_size: 1325142016 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Stromal Connective tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:27:00.004560+0000 requires: - segway_group size: 1325154305 tags: - non coding title: Segway Stromal Connective type: annotator versions: - 1.0.0 - 1.2.0 segway_thymus: code_size: 11905 commercial_warning: null data_size: 714776576 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Thymus tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:27:47.185959+0000 requires: - segway_group size: 714788481 tags: - non coding title: Segway Thymus type: annotator versions: - 1.0.0 - 1.2.0 segway_vascular: code_size: 11633 commercial_warning: null data_size: 296783872 data_sources: 1.0.0: 2019.09.01 1.2.0: 2019.09.01 data_versions: 1.0.0: 1.0.0 1.2.0: 1.0.0 datasource: 2019.09.01 description: Chromatin state for Vascular tissues developer: citation: 'Libbrecht, Maxwell W., et al. "A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types." Genome Biology 20.1 (2019): 1-14.' email: michael.hoffman@utoronto.ca name: Michael Hoffman organization: Princess Margaret Cancer Centre website: https://segway.hoffmanlab.org/ groups: - segway_group has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2020-09-12T20:28:34.447763+0000 requires: - segway_group size: 296795505 tags: - non coding title: Segway Vascular type: annotator versions: - 1.0.0 - 1.2.0 sift: code_size: 24454 commercial_warning: Freely available to the academic community. Commercial licensees should contact Steven Henikoff. data_size: 21874354180 data_sources: 1.0.0: SIFT4G 2016-02-22 1.1.0: SIFT4G 2016-02-22 1.2.0: SIFT4G 2016-02-22 1.3.0: SIFT4G 2016-02-22 data_versions: 1.0.0: 1.0.0 1.1.0: 1.1.0 1.2.0: 1.1.0 1.3.0: 1.1.0 datasource: SIFT4G 2016-02-22 description: SIFT predicts whether an amino acid substitution affects protein function developer: citation: 'Vaser R, Adusumalli S, Leng SN, Sikic M, Ng PC (2016) SIFT missense predictions for genomes. Nat Protocols 11: 1-9.' email: ngpc4@gis.a-star.edu.sg name: Pauline Ng organization: Bioinformatics Institute, Agency for Science, Technology and Research, Singapore website: sift.bii.a-star.edu.sg groups: [] has_logo: true hidden: false latest_version: 1.3.0 publish_time: 2020-11-10T20:41:21.626925+0000 requires: - wgsift size: 21874378634 tags: - variant effect prediction - variants - clinical relevance title: SIFT type: annotator versions: - 1.0.0 - 1.1.0 - 1.2.0 - 1.3.0 siphy: code_size: 45817 commercial_warning: null data_size: 5569429504 data_sources: 3.5.0: 3.5.0 3.5.1: dbNSFP v4.0b1 3.5.2: dbNSFP v4.0b1 3.5.3: dbNSFP v4.0b1 3.5.4: dbNSFP v4.0b1 3.5.5: dbNSFP v4.0b1 data_versions: 3.5.0: 3.5.0 3.5.1: 3.5.0 3.5.2: 3.5.0 3.5.3: 3.5.0 3.5.4: 3.5.0 3.5.5: 3.5.0 datasource: dbNSFP v4.0b1 description: A database of conservation scores based on 29 mammal genomes developer: citation: Lindblad-Toh, K., Garber, M., Zuk, et al. (2011). A high-resolution map of human evolutionary constraint using 29 mammals. Nature, 478(7370), 476. email: support@opencravat.org name: '' organization: Broad Institute website: https://www.broadinstitute.org/mammals-models/29-mammals-project groups: [] has_logo: true hidden: false latest_version: 3.5.5 publish_time: 2019-01-30T18:45:33.527748+0000 requires: - wgsiphy size: 5569475321 tags: - variants - evolution title: SiPhy type: annotator versions: - 3.5.0 - 3.5.1 - 3.5.2 - 3.5.3 - 3.5.4 - 3.5.5 spliceai: code_size: 204344 commercial_warning: Freely available for non-commercial use. data_size: 1808545796 data_sources: 1.0.0: v4.0 data_versions: 1.0.0: 1.0.0 datasource: v4.0 description: A deep neural network that accurately predicts splice junctions from an arbitrary pre-mRNA transcript sequence, enabling precise prediction of noncoding genetic variants that cause cryptic splicing. developer: citation: 'Jaganathan, Kishore, et al. "Predicting splicing from primary sequence with deep learning." Cell 176.3 (2019): 535-548.' email: support@opencravat.org name: illumina organization: illumina website: https://sites.google.com/site/jpopgen/dbNSFP groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-12-17T20:39:58.457299+0000 requires: null size: 1808750140 tags: - variant effect prediction - variants title: SpliceAI type: annotator versions: - 1.0.0 splicing: code_size: 1009649 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: Package that identifies variants related to splicing. developer: citation: '' email: support@opencravat.org name: OpenCRAVAT Team organization: KarchinLab website: https://opencravat.org groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2023-03-13T13:27:37.582973+0000 requires: - dbscsnv - spliceai - ncbigene - tsvreporter size: 1009649 tags: null title: Splicing Package type: package versions: - 1.0.0 stdoutreporter: code_size: 1069 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null data_versions: 1.0.0: null 1.0.1: null datasource: null description: STDOUT reporter developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.1 publish_time: 2020-07-14T13:33:05.362044+0000 requires: null size: 1069 tags: - reporters title: STDOUT Reporter type: reporter versions: - 1.0.0 - 1.0.1 swissprot_binding: code_size: 230088 commercial_warning: null data_size: 2799620 data_sources: 1.0.0: 12.02.2020 data_versions: 1.0.0: 1.0.0 datasource: 12.02.2020 description: Provides any useful information about the protein, mostly binding sites. developer: citation: "The UniProt Consortium, UniProt: a hub for protein information, Nucleic\ \ Acids Research, Volume 43, Issue D1, 28 January 2015, Pages D204\u2013D212,\ \ https://doi.org/10.1093/nar/gku989" email: support@opencravat.org name: The UniProt Consortium organization: The UniProt Consortium website: https://www.uniprot.org/help/function_section groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-12-17T20:39:58.523326+0000 requires: - wgswissprot_binding size: 3029708 tags: - functional studies title: Swiss-Prot Binding type: annotator versions: - 1.0.0 swissprot_domains: code_size: 230122 commercial_warning: null data_size: 11978756 data_sources: 1.0.0: 12.02.2020 1.1.0: 02.01.2024 data_versions: 1.0.0: 1.0.0 1.1.0: 1.1.0 datasource: 02.01.2024 description: Provides information on location,topology, and domain(s) of a protein. developer: citation: "The UniProt Consortium, UniProt: a worldwide hub of protein knowledge,\ \ Nucleic Acids Research, Volume 47, Issue D1, 08 January 2019, Pages D506\u2013\ D515, https://doi.org/10.1093/nar/gky1049" email: support@opencravat.org name: The UniProt Consortium organization: The UniProt Consortium website: https://www.uniprot.org/help/family_and_domains_section groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2024-12-17T20:41:51.457815+0000 requires: - wgswissprot_domains size: 12208878 tags: - functional studies title: Swiss-Prot Domains type: annotator versions: - 1.0.0 - 1.1.0 swissprot_ptm: code_size: 407839 commercial_warning: null data_size: 7464964 data_sources: 1.0.0: 2018.04.10 1.0.1: 2018.04.10 1.1.0: 2018.04.10 1.2.0: 2024.02.01 data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.1.0: 1.1.0 1.2.0: 1.2.0 datasource: 2024.02.01 description: A high quality manually annotated protein sequence database, specifying in post-translational modifications (PTMs). developer: citation: 'Khoury, George A., Richard C. Baliban, and Christodoulos A. Floudas. "Proteome-wide post-translational modification statistics: frequency analysis and curation of the swiss-prot database." Scientific reports 1 (2011): 90.' email: support@opencravat.org name: The UniProt Consortium organization: The UniProt Consortium website: https://www.uniprot.org/help/ptm_processing_section groups: [] has_logo: true hidden: false latest_version: 1.2.0 publish_time: 2024-12-17T20:41:51.546856+0000 requires: - wgswissprot_ptm size: 7872803 tags: - functional studies title: Swiss-Prot PTM type: annotator versions: - 1.0.0 - 1.0.1 - 1.1.0 - 1.2.0 tagsampler: code_size: 3110 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.10: null 1.0.11: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.0.6: null 1.0.7: null 1.0.8: null 1.1.0: null 1.1.1: null 1.1.2: null 1.1.3: null 1.1.4: null 1.1.5: null 1.1.6: null data_versions: 1.0.0: null 1.0.1: null 1.0.10: null 1.0.11: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.0.6: null 1.0.7: null 1.0.8: null 1.1.0: null 1.1.1: null 1.1.2: null 1.1.3: null 1.1.4: null 1.1.5: null 1.1.6: null datasource: null description: Aggregates tags and samples developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.1.6 publish_time: '2018-07-24T19:44:47.000000' requires: null size: 3110 tags: null title: Tag Sampler type: postaggregator versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.0.5 - 1.0.6 - 1.0.7 - 1.0.8 - 1.0.10 - 1.0.11 - 1.1.0 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.1.5 - 1.1.6 target: code_size: 23205 commercial_warning: null data_size: 26628 data_sources: 1.0.0: null 3.0.0: null 3.0.1: null 3.0.11: 3.0.1 3.0.12: 3.0.1 3.0.13: v3.0.1 3.0.14: v3.0.1 3.0.15: v3.0.1 3.0.16: v3.0.1 3.0.17: v3.0.1 3.1.0: v3.0.1 data_versions: 1.0.0: 1.0.0 3.0.0: 1.0.0 3.0.1: 1.0.0 3.0.11: 1.0.0 3.0.12: 1.0.0 3.0.13: 1.0.0 3.0.14: 1.0.0 3.0.15: 1.0.0 3.0.16: 1.0.0 3.0.17: 1.0.0 3.1.0: 3.1.0 datasource: v3.0.1 description: Tumor Alterations Relevant for GEnomics-driven Therapy developer: citation: Van Allen, E. M., Wagle, N., Stojanov, P., et al. (2014). Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine. Nature medicine, 20(6), 682. email: support@opencravat.org name: Broad Institute organization: Broad Institute website: https://software.broadinstitute.org/cancer/cga/target groups: [] has_logo: true hidden: false latest_version: 3.1.0 publish_time: 2019-01-30T18:45:59.292148+0000 requires: - wgtarget size: 49833 tags: - genes - cancer title: TARGET type: annotator versions: - 1.0.0 - 3.0.0 - 3.0.1 - 3.0.11 - 3.0.12 - 3.0.13 - 3.0.14 - 3.0.15 - 3.0.16 - 3.0.17 - 3.1.0 textreporter: code_size: 241980 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.4: null 1.0.5: null 1.0.6: null 1.0.7: null 2.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.4: null 1.0.5: null 1.0.6: null 1.0.7: null 2.1.0: null datasource: null description: Text format reporter developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 2.1.0 publish_time: '2018-08-14T15:06:06.000000' requires: null size: 241980 tags: - input/output title: Text Reporter type: reporter versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.4 - 1.0.5 - 1.0.6 - 1.0.7 - 2.1.0 thousandgenomes: code_size: 418692 commercial_warning: null data_size: 5291798528 data_sources: 1.0.0: null 3.0.0: null 3.0.1: null 3.0.2: null 3.0.3: null 3.0.4: Phase 3 3.0.5: Phase 3 3.1.0: Phase 3 4.0.1: Phase 3 4.0.2: Phase 3 4.0.4: Phase 3 4.0.5: Phase 3 4.1.0: Phase 3 data_versions: 1.0.0: 1.0.0 3.0.0: 1.0.0 3.0.1: 1.0.0 3.0.2: 1.0.0 3.0.3: 1.0.0 3.0.4: 1.0.0 3.0.5: 1.0.0 3.1.0: 3.1.0 4.0.1: 3.1.0 4.0.2: 4.0.2 4.0.4: 4.0.2 4.0.5: 4.0.2 4.1.0: 4.0.2 datasource: Phase 3 description: Population allele frequencies from 1000 Genomes Project developer: citation: 1000 Genomes Project Consortium. (2015). A global reference for human genetic variation. Nature, 526(7571), 68. email: support@opencravat.org name: 1000 Genomes Project Consortium organization: 1000 Genomes Project Consortium website: http://www.internationalgenome.org/home groups: - thousandgenomes_group has_logo: true hidden: false latest_version: 4.1.0 publish_time: 2019-01-30T18:46:33.377326+0000 requires: - wgthousandgenomes - thousandgenomes_group size: 5292217220 tags: - allele frequency title: 1000 Genomes type: annotator versions: - 1.0.0 - 3.0.0 - 3.0.1 - 3.0.2 - 3.0.3 - 3.0.4 - 3.0.5 - 3.1.0 - 4.0.1 - 4.0.2 - 4.0.4 - 4.0.5 - 4.1.0 thousandgenomes_ad_mixed_american: code_size: 507288 commercial_warning: null data_size: 4097593344 data_sources: 3.1.0: Phase 3 3.1.1: Phase 3 3.1.3: Phase 3 4.1.0: Phase 3 4.1.1: Phase 3 data_versions: 3.1.0: 3.1.0 3.1.1: 3.1.1 3.1.3: 3.1.1 4.1.0: 3.1.1 4.1.1: 3.1.1 datasource: Phase 3 description: Population allele frequencies from 1000 Genomes Project developer: citation: 1000 Genomes Project Consortium. (2015). A global reference for human genetic variation. Nature, 526(7571), 68. email: support@opencravat.org name: 1000 Genomes Project Consortium organization: 1000 Genomes Project Consortium website: http://www.internationalgenome.org/home groups: - thousandgenomes_group has_logo: true hidden: false latest_version: 4.1.1 publish_time: 2019-06-07T18:59:59.557670+0000 requires: - thousandgenomes_group - wgthousandgenomes_ad_mixed_american size: 4098100632 tags: - allele frequency title: 1000 Genomes-Ad Mixed American type: annotator versions: - 3.1.0 - 3.1.1 - 3.1.3 - 4.1.0 - 4.1.1 thousandgenomes_african: code_size: 418518 commercial_warning: null data_size: 5269155840 data_sources: 3.1.0: Phase 3 3.1.1: Phase 3 3.1.3: Phase 3 3.1.4: Phase 3 4.1.0: Phase 3 4.1.1: Phase 3 data_versions: 3.1.0: 3.1.0 3.1.1: 3.1.1 3.1.3: 3.1.1 3.1.4: 3.1.1 4.1.0: 3.1.1 4.1.1: 3.1.1 datasource: Phase 3 description: Population allele frequencies from 1000 Genomes Project developer: citation: 1000 Genomes Project Consortium. (2015). A global reference for human genetic variation. Nature, 526(7571), 68. email: support@opencravat.org name: 1000 Genomes Project Consortium organization: 1000 Genomes Project Consortium website: http://www.internationalgenome.org/home groups: - thousandgenomes_group has_logo: true hidden: false latest_version: 4.1.1 publish_time: 2019-06-07T19:00:17.976738+0000 requires: - thousandgenomes_group - wgthousandgenomes_african size: 5269574358 tags: - allele frequency title: 1000 Genomes-African type: annotator versions: - 3.1.0 - 3.1.1 - 3.1.3 - 3.1.4 - 4.1.0 - 4.1.1 thousandgenomes_east_asian: code_size: 418068 commercial_warning: null data_size: 4120207360 data_sources: 3.1.0: Phase 3 3.1.1: Phase 3 3.1.3: Phase 3 4.1.0: Phase 3 4.1.1: Phase 3 data_versions: 3.1.0: 3.1.0 3.1.1: 3.1.1 3.1.3: 3.1.1 4.1.0: 3.1.1 4.1.1: 3.1.1 datasource: Phase 3 description: Population allele frequencies from 1000 Genomes Project developer: citation: 1000 Genomes Project Consortium. (2015). A global reference for human genetic variation. Nature, 526(7571), 68. email: support@opencravat.org name: 1000 Genomes Project Consortium organization: 1000 Genomes Project Consortium website: http://www.internationalgenome.org/home groups: - thousandgenomes_group has_logo: true hidden: false latest_version: 4.1.1 publish_time: 2019-06-07T19:00:35.927973+0000 requires: - thousandgenomes_group - wgthousandgenomes_east_asian size: 4120625428 tags: - allele frequency title: 1000 Genomes-East Asian type: annotator versions: - 3.1.0 - 3.1.1 - 3.1.3 - 4.1.0 - 4.1.1 thousandgenomes_european: code_size: 418048 commercial_warning: null data_size: 4173643776 data_sources: 3.1.0: Phase 3 3.1.1: Phase 3 3.1.3: Phase 3 4.1.0: Phase 3 4.1.1: Phase 3 data_versions: 3.1.0: 3.1.0 3.1.1: 3.1.1 3.1.3: 3.1.1 4.1.0: 3.1.1 4.1.1: 3.1.1 datasource: Phase 3 description: Population allele frequencies from 1000 Genomes Project developer: citation: 1000 Genomes Project Consortium. (2015). A global reference for human genetic variation. Nature, 526(7571), 68. email: support@opencravat.org name: 1000 Genomes Project Consortium organization: 1000 Genomes Project Consortium website: http://www.internationalgenome.org/home groups: - thousandgenomes_group has_logo: true hidden: false latest_version: 4.1.1 publish_time: 2019-06-07T19:00:53.753998+0000 requires: - thousandgenomes_group - wgthousandgenomes_european size: 4174061824 tags: - allele frequency title: 1000 Genomes-European type: annotator versions: - 3.1.0 - 3.1.1 - 3.1.3 - 4.1.0 - 4.1.1 thousandgenomes_group: code_size: 17643 commercial_warning: null data_size: 0 data_sources: 3.1.0: Phase 3 data_versions: 3.1.0: null datasource: Phase 3 description: Population allele frequencies from 1000 Genomes Project developer: citation: 1000 Genomes Project Consortium. (2015). A global reference for human genetic variation. Nature, 526(7571), 68. email: support@opencravat.org name: 1000 Genomes Project Consortium organization: 1000 Genomes Project Consortium website: http://www.internationalgenome.org/home groups: [] has_logo: true hidden: false latest_version: 3.1.0 publish_time: 2024-12-17T20:45:37.567986+0000 requires: null size: 17643 tags: - allele frequency title: 1000 Genomes type: group versions: - 3.1.0 thousandgenomes_south_asian: code_size: 418013 commercial_warning: null data_size: 4243808256 data_sources: 3.1.0: Phase 3 3.1.1: Phase 3 3.1.3: Phase 3 4.1.0: Phase 3 4.1.1: Phase 3 data_versions: 3.1.0: 3.1.0 3.1.1: 3.1.1 3.1.3: 3.1.1 4.1.0: 3.1.1 4.1.1: 3.1.1 datasource: Phase 3 description: Population allele frequencies from 1000 Genomes Project developer: citation: 1000 Genomes Project Consortium. (2015). A global reference for human genetic variation. Nature, 526(7571), 68. email: support@opencravat.org name: 1000 Genomes Project Consortium organization: 1000 Genomes Project Consortium website: http://www.internationalgenome.org/home groups: - thousandgenomes_group has_logo: true hidden: false latest_version: 4.1.1 publish_time: 2019-06-07T19:15:43.009947+0000 requires: - thousandgenomes_group - wgthousandgenomes_south_asian size: 4244226269 tags: - allele frequency title: 1000 Genomes-South Asian type: annotator versions: - 3.1.0 - 3.1.1 - 3.1.3 - 4.1.0 - 4.1.1 trinity: code_size: 102761 commercial_warning: null data_size: 59396 data_sources: 1.0.0: 26 February 2020 data_versions: 1.0.0: 1.0.0 datasource: 26 February 2020 description: Trinity assembles transcript sequences from Illumina RNA-Seq data. developer: citation: 'Grabherr MG, Haas BJ, Yassour M, Levin JZ, Thompson DA, Amit I, Adiconis X, Fan L, Raychowdhury R, Zeng Q, Chen Z, Mauceli E, Hacohen N, Gnirke A, Rhind N, di Palma F, Birren BW, Nusbaum C, Lindblad-Toh K, Friedman N, Regev A. Full-length transcriptome assembly from RNA-seq data without a reference genome. Nat Biotechnol. 2011 May 15;29(7):644-52. doi: 10.1038/nbt.1883. PubMed PMID: 21572440.' email: support@opencravat.org name: Broad Institute organization: Broad Institute website: https://data.broadinstitute.org/Trinity/CTAT_RESOURCE_LIB/MUTATION_LIB_SUPPLEMENT/rna_editing/ groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-12-17T20:43:44.674610+0000 requires: null size: 162157 tags: - non coding title: Trinity CTAT type: annotator versions: - 1.0.0 tsvreporter: code_size: 263314 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.10: null 1.0.2: null 1.0.4: null 1.0.5: null 1.0.7: null 1.0.8: null 1.0.9: null 2.0.0: null 2.0.2: null 2.0.3: null 2.0.4: null 2.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.10: null 1.0.2: null 1.0.4: null 1.0.5: null 1.0.7: null 1.0.8: null 1.0.9: null 2.0.0: null 2.0.2: null 2.0.3: null 2.0.4: null 2.1.0: null datasource: null description: Tab-delimited format text file reporter developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: false latest_version: 2.1.0 publish_time: 2019-06-12T17:11:00.368964+0000 requires: null size: 263314 tags: - input/output title: TSV Reporter type: reporter versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.4 - 1.0.5 - 1.0.7 - 1.0.8 - 1.0.9 - 1.0.10 - 2.0.0 - 2.0.2 - 2.0.3 - 2.0.4 - 2.1.0 ucscgenomebrowser: code_size: 1718 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: Link to UCSC Genome Browser developer: citation: ' UCSC Genome Browser: Kent WJ, Sugnet CW, Furey TS, Roskin KM, Pringle TH, Zahler AM, Haussler D. The human genome browser at UCSC. Genome Res. 2002 Jun;12(6):996-1006.' email: support@opencravat.org name: UCSC organization: UCSC website: https://genome.ucsc.edu/ groups: [] has_logo: false hidden: false latest_version: 1.1.0 publish_time: 2023-08-03T17:58:31.667838+0000 requires: null size: 1718 tags: null title: UCSC Genome Browser type: annotator versions: - 1.0.0 - 1.1.0 uk10k_cohort: code_size: 57640 commercial_warning: null data_size: 16308228 data_sources: 3.5.0: null 3.5.01: null 3.5.02: null 3.5.03: null 3.5.04: dbNSFP v4.0b1 3.5.05: dbNSFP v4.0b1 3.5.06: dbNSFP v4.0b1 3.5.7: dbNSFP v4.0b1 3.5.8: dbNSFP v4.0b1 3.5.9: dbNSFP v4.0b1 data_versions: 3.5.0: 3.5.0 3.5.01: 3.5.0 3.5.02: 3.5.0 3.5.03: 3.5.0 3.5.04: 3.5.0 3.5.05: 3.5.0 3.5.06: 3.5.06 3.5.7: 3.5.06 3.5.8: 3.5.06 3.5.9: 3.5.06 datasource: dbNSFP v4.0b1 description: UK10K cohort provides genetic information from DTR & ALSPAC developer: citation: UK10K consortium. (2015). The UK10K project identifies rare variants in health and disease. Nature, 526(7571), 82. email: support@opencravat.org name: UK10K Consortium organization: Wellcome Sanger Institute website: https://www.uk10k.org/studies/cohorts.html groups: [] has_logo: true hidden: false latest_version: 3.5.9 publish_time: 2019-01-30T18:46:41.583710+0000 requires: - wguk10k_cohort size: 16365868 tags: - allele frequency title: UK10k Cohorts type: annotator versions: - 3.5.0 - 3.5.01 - 3.5.02 - 3.5.03 - 3.5.04 - 3.5.05 - 3.5.06 - 3.5.7 - 3.5.8 - 3.5.9 uniprot: code_size: 11488 commercial_warning: null data_size: 768004 data_sources: 2018.9.0: 4.0.0 2018.9.1: 201809 2019.02.011: 201809 2019.02.06: 201809 2019.02.13: 201809 2019.03.20: 201809 2019.03.26: 201809 2019.05.13: 201809 2019.08.22: '201809' 2020.08.10: '201809' data_versions: 2018.9.0: 2018.9.0 2018.9.1: 2018.9.0 2019.02.011: 2018.9.0 2019.02.06: 2018.9.0 2019.02.13: 2018.9.0 2019.03.20: 2018.9.0 2019.03.26: 2018.9.0 2019.05.13: 2018.9.0 2019.08.22: 2018.9.0 2020.08.10: 2020.08.10 datasource: '201809' description: Comprehensive resource for protein sequence and functional information. developer: citation: 'UniProt Consortium. (2018). UniProt: the universal protein knowledgebase. Nucleic acids research, 46(5), 2699.' email: support@opencravat.org name: The UniProt Consortium organization: The UniProt Consortium website: https://www.uniprot.org/ groups: [] has_logo: true hidden: false latest_version: 2020.08.10 publish_time: 2019-12-18T16:06:24.880670+0000 requires: null size: 779492 tags: - literature title: UniProt type: annotator versions: - 2018.9.0 - 2018.9.1 - 2019.02.06 - 2019.02.011 - 2019.02.13 - 2019.03.20 - 2019.03.26 - 2019.05.13 - 2019.08.22 - 2020.08.10 uniprot_domain: code_size: 6192 commercial_warning: null data_size: 7157414 data_sources: 1.0.0: null data_versions: 1.0.0: 1.0.0 datasource: null description: Protein domains from UniProt developer: citation: "The UniProt Consortium , UniProt: the Universal Protein Knowledgebase\ \ in 2023, Nucleic Acids Research, Volume 51, Issue D1, 6 January 2023, Pages\ \ D523\u2013D531, https://doi.org/10.1093/nar/gkac1052" email: support@opencravat.org name: UniProt organization: EMBL-EBI website: https://www.uniprot.org/ groups: [] has_logo: true hidden: false latest_version: 1.0.0 publish_time: 2024-03-06T14:56:00.411841+0000 requires: null size: 7163606 tags: - literature - variants title: Uniprot Domain type: annotator versions: - 1.0.0 variantreport: code_size: 8027318 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.0.6: null 1.0.7: null 1.0.8: null 1.1.0: null 1.1.1: null 1.2.0: null 1.2.1: null 1.2.2: null 1.3.0: null 1.4.0: null 1.4.1: null 1.5.0: null 1.5.1: null 1.6.0: null 1.6.1: null 1.6.2: null 1.6.3: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.0.6: null 1.0.7: null 1.0.8: null 1.1.0: null 1.1.1: null 1.2.0: null 1.2.1: null 1.2.2: null 1.3.0: null 1.4.0: null 1.4.1: null 1.5.0: null 1.5.1: null 1.6.0: null 1.6.1: null 1.6.2: null 1.6.3: null datasource: null description: OpenCRAVAT Variant Report Webapp developer: citation: '' email: support@opencravat.org name: OpenCravat organization: KarchinLab website: null groups: [] has_logo: true hidden: false latest_version: 1.6.3 publish_time: 2021-05-13T15:43:43.519979+0000 requires: - 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wgvcfinfo size: 6509 tags: null title: VCF Info type: postaggregator versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.0.5 - 1.0.6 - 1.0.7 - 1.1.0 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.1.5 - 2.0.0 vcfreporter: code_size: 274195 commercial_warning: null data_size: 0 data_sources: 1.0.1: null 1.0.10: null 1.0.11: null 1.0.12: null 1.0.13: null 1.0.14: null 1.0.15: null 1.0.17: null 1.0.18: null 1.0.19: null 2.1.0: null 2.1.1: null 2.1.2: null 2.1.3: null 2.2.0: null 3.0.0: null 3.1.0: null 3.2.0: null 3.2.1: null data_versions: 1.0.1: null 1.0.10: null 1.0.11: null 1.0.12: null 1.0.13: null 1.0.14: null 1.0.15: null 1.0.17: null 1.0.18: null 1.0.19: null 2.1.0: null 2.1.1: null 2.1.2: null 2.1.3: null 2.2.0: null 3.0.0: null 3.1.0: null 3.2.0: null 3.2.1: null datasource: null description: VCF format text file reporter developer: citation: '' email: rkim@oakbioinformatics.com name: Ryangguk Kim organization: Oak Bioinformatics LLC website: https://www.oakbioinformatics.com groups: [] has_logo: true hidden: false latest_version: 3.2.1 publish_time: 2020-01-30T19:14:31.701795+0000 requires: null size: 274195 tags: - input/output title: VCF Reporter type: reporter versions: - 1.0.1 - 1.0.10 - 1.0.11 - 1.0.12 - 1.0.13 - 1.0.14 - 1.0.15 - 1.0.17 - 1.0.18 - 1.0.19 - 2.1.0 - 2.1.1 - 2.1.2 - 2.1.3 - 2.2.0 - 3.0.0 - 3.1.0 - 3.2.0 - 3.2.1 vest: code_size: 1377374 commercial_warning: null data_size: 9748356693 data_sources: 4.0.0: null 4.0.1: null 4.0.2: v4 4.0.4: v4 4.0.5: v4 4.0.6: v4 4.0.7: v4 4.0.8: v4 4.0.9: v4 4.1.0: v4 4.1.1: v4 4.1.2: v4 4.2.0: v4 4.3.0: v4 4.3.1: v4 4.3.3: v4 4.4.0: v4 4.5.0: v4 4.5.1: v4 data_versions: 4.0.0: 4.0.0 4.0.1: 4.0.0 4.0.2: 4.0.0 4.0.4: 4.0.0 4.0.5: 4.0.0 4.0.6: 4.0.0 4.0.7: 4.0.0 4.0.8: 4.0.0 4.0.9: 4.0.0 4.1.0: 4.0.0 4.1.1: 4.0.0 4.1.2: 4.0.0 4.2.0: 4.0.0 4.3.0: 4.0.0 4.3.1: 4.0.0 4.3.3: 4.0.0 4.4.0: 4.0.0 4.5.0: 4.0.0 4.5.1: 4.0.0 datasource: v4 description: VEST annotation developer: citation: Carter H, Douville C, Stenson PD, Cooper DN, Karchin R. Identifying Mendelian disease genes with the variant effect scoring tool. BMC Genomics. 2013;14 Suppl 3(Suppl 3):S3. email: '' name: Johns Hopkins University - Karchin Lab organization: Johns Hopkins University - Karchin Lab website: '' groups: [] has_logo: true hidden: false latest_version: 4.5.1 publish_time: 2019-01-30T18:47:42.647635+0000 requires: - wgvest size: 9749734067 tags: - variants - variant effect prediction - clinical relevance title: VEST4 type: annotator versions: - 4.0.0 - 4.0.1 - 4.0.2 - 4.0.4 - 4.0.5 - 4.0.6 - 4.0.7 - 4.0.8 - 4.0.9 - 4.1.0 - 4.1.1 - 4.1.2 - 4.2.0 - 4.3.0 - 4.3.1 - 4.3.3 - 4.4.0 - 4.5.0 - 4.5.1 vista_enhancer: code_size: 19316 commercial_warning: For commercial use, contact vtdelapuente@lbl.gov data_size: 108548 data_sources: 2019.05.09: hg19 2019.08.02: hg19 2019.2.5: hg19 2019.3.22: hg19 2019.3.4: hg19 data_versions: 2019.05.09: 2019.3.22 2019.08.02: 2019.3.22 2019.2.5: 2019.2.5 2019.3.22: 2019.3.22 2019.3.4: 2019.2.5 datasource: hg19 description: Experimentally validated enhancers from the VISTA Enhancer Browser developer: citation: "Visel, A., Minovitsky, S., Dubchak, I., & Pennacchio, L. A. (2006).\ \ VISTA Enhancer Browser\u2014a database of tissue-specific human enhancers.\ \ Nucleic acids research, 35(suppl_1), D88-D92." email: vtdelapuente@lbl.gov name: Lawrence Berkeley National Laboratory organization: Lawrence Berkeley National Laboratory website: https://enhancer.lbl.gov/ groups: [] has_logo: true hidden: false latest_version: 2019.08.02 publish_time: 2019-02-11T20:10:23.260495+0000 requires: null size: 127864 tags: - non coding - functional studies title: VISTA Enhancer Browser type: annotator versions: - 2019.2.5 - 2019.3.4 - 2019.3.22 - 2019.05.09 - 2019.08.02 wgallelefrequency: code_size: 109238 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: Allele Frequency Spectrum webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2021-02-26T16:38:51.841220+0000 requires: null size: 109238 tags: - 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visualization title: DGIdb type: webviewerwidget versions: - 1.0.0 wgdida: code_size: 4177 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: DIDA webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.0.0 publish_time: 2021-06-24T18:40:50.838588+0000 requires: null size: 4177 tags: - visualization title: DIDA type: webviewerwidget versions: - 1.0.0 wgditto: code_size: 127075 commercial_warning: null data_size: 0 data_sources: 0.0.3: null data_versions: 0.0.3: null datasource: null description: DITTO webviewer widget developer: citation: 'Mamidi, T.K.K.; Wilk, B.M.; Gajapathy, M.; Worthey, E.A. DITTO: An Explainable Machine-Learning Model for Transcript-Specific Variant Pathogenicity Prediction. Preprints 2024, 2024040837. https://doi.org/10.20944/preprints202404.0837.v1' email: tmamidi@uab.edu name: Tarun Mamidi organization: The University of Alabama at Birmingham website: https://github.com/uab-cgds-worthey/DITTO groups: [] has_logo: false hidden: false latest_version: 0.0.3 publish_time: 2025-06-18T18:16:13.516615+0000 requires: null size: 127075 tags: - visualization title: DITTO type: webviewerwidget versions: - 0.0.3 wgencode_tfbs: code_size: 1549 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: ENCODE TFBS webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.0 publish_time: 2021-01-13T20:09:46.608938+0000 requires: null size: 1549 tags: - visualization title: ENCODE TFBS type: webviewerwidget versions: - 1.0.0 wgenhancer: code_size: 48703 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: Frequently Mutated Enhancers webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2021-02-26T16:37:42.480776+0000 requires: null size: 48703 tags: - visualization title: Frequently Mutated Enhancers type: webviewerwidget versions: - 1.0.0 - 1.1.0 wgensembl_regulatory_build: code_size: 1269 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: Ensembl Regulatory Build webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.0 publish_time: 2021-01-13T16:22:41.349629+0000 requires: null size: 1269 tags: - visualization title: Ensembl Regulatory Build type: webviewerwidget versions: - 1.0.0 wgesm1b: code_size: 1893 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: esm1b webviewer widget developer: citation: '' email: support@opencravat.org name: OpenCRAVAT Team organization: KarchinLab website: https://opencravat.org groups: [] has_logo: false hidden: false latest_version: 1.1.0 publish_time: 2024-05-09T16:27:58.656499+0000 requires: null size: 1893 tags: - visualization title: ESM1b type: webviewerwidget versions: - 1.0.0 - 1.1.0 wgesp6500: code_size: 16984 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null data_versions: 1.0.0: null 1.0.1: null datasource: null description: ESP6500 webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.0.1 publish_time: 2019-05-06T20:17:28.803767+0000 requires: null size: 16984 tags: - visualization title: ESP6500 type: webviewerwidget versions: - 1.0.0 - 1.0.1 wgess_gene: code_size: 865 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null datasource: null description: Essential Gene webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.1.0 publish_time: '2018-12-05T18:37:27.000000' requires: null size: 865 tags: - visualization title: Essential Gene type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 wgexac_gene: code_size: 847 commercial_warning: null data_size: 0 data_sources: 1.1.0: null data_versions: 1.1.0: null datasource: null description: ExAC Gene widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.1.0 publish_time: 2020-09-14T19:54:34.101641+0000 requires: null size: 847 tags: - visualization title: ExAC Gene type: webviewerwidget versions: - 1.1.0 wgfathmm: code_size: 3075 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null 1.2.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null 1.2.0: null datasource: null description: FATHMM webviewer widget developer: citation: '' email: support@opencravat.org name: OpenCRAVAT Team organization: KarchinLab website: https://opencravat.org groups: [] has_logo: false hidden: true latest_version: 1.2.0 publish_time: '2018-11-26T19:32:50.000000' requires: null size: 3075 tags: - visualization title: FATHMM type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.1.0 - 1.2.0 wgfunseq2: code_size: 1515 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: FunSeq2 webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.0.0 publish_time: 2021-04-02T17:18:10.852235+0000 requires: null size: 1515 tags: - visualization title: FunSeq2 type: webviewerwidget versions: - 1.0.0 wggenehancer: code_size: 1409 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null data_versions: 1.0.0: null 1.0.1: null datasource: null description: GeneHancer webviewer widget developer: citation: '' email: support@opencravat.org name: OpenCRAVAT developers organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.1 publish_time: 2020-09-14T19:54:34.127769+0000 requires: null size: 1409 tags: - visualization title: GeneHancer type: webviewerwidget versions: - 1.0.0 - 1.0.1 wggerp: code_size: 1120 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null datasource: null description: GERP++ web viewer widget developer: citation: '' email: support@opencravat.org name: OpenCRAVAT Team organization: KarchinLab website: https://opencravat.org groups: [] has_logo: false hidden: true latest_version: 1.1.0 publish_time: '2018-12-11T20:29:41.000000' requires: null size: 1120 tags: - visualization title: GERP++ type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.1.0 wgghis: code_size: 541 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null datasource: null description: GHIS webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.3 publish_time: '2018-11-29T17:04:37.000000' requires: null size: 541 tags: - visualization title: GHIS type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 wggnomad: code_size: 23818 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 1.1.1: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 1.1.1: null datasource: null description: gnomAD webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.1 publish_time: '2018-10-26T20:49:59.000000' requires: null size: 23818 tags: - visualization title: gnomAD type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 - 1.1.1 wggnomad3: code_size: 23798 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: gnomAD3 webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.0 publish_time: 2020-09-14T19:54:34.177886+0000 requires: null size: 23798 tags: - visualization title: gnomAD3 type: webviewerwidget versions: - 1.0.0 - 1.1.0 wggnomad_gene: code_size: 24017 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.1.0: null 1.1.1: null 1.2.0: null 1.2.1: null data_versions: 1.0.0: null 1.0.1: null 1.1.0: null 1.1.1: null 1.2.0: null 1.2.1: null datasource: null description: gnomAD Gene webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.2.1 publish_time: 2019-05-06T20:19:14.905227+0000 requires: null size: 24017 tags: - visualization title: gnomAD Gene type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.1.0 - 1.1.1 - 1.2.0 - 1.2.1 wggo: code_size: 11653 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.1.0: null 1.2.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.1.0: null 1.2.0: null datasource: null description: Gene ontology webviewer widget developer: email: rkim@mail.insilico.us.com organization: In Silico Solutions groups: [] has_logo: true hidden: true latest_version: 1.2.0 publish_time: '2018-05-18T14:23:01.000000' requires: null size: 11653 tags: - visualization title: Gene ontology type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.0.5 - 1.1.0 - 1.2.0 wggosummary: code_size: 18036 commercial_warning: null data_size: 38819844 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.0.6: null 1.0.7: null 1.0.8: null 2.0.2: null 2.0.3: null 2.1.0: null 2.1.1: null 2.2.0: null 2.3.0: null 2.4.0: null data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.0.2: 1.0.0 1.0.3: 1.0.0 1.0.4: 1.0.0 1.0.5: 1.0.0 1.0.6: 1.0.0 1.0.7: 1.0.0 1.0.8: 1.0.0 2.0.2: 1.0.0 2.0.3: 1.0.0 2.1.0: 1.0.0 2.1.1: 2.1.1 2.2.0: 2.1.1 2.3.0: 2.1.1 2.4.0: 2.1.1 datasource: null description: Gene Ontology Summary webviewer widget developer: citation: '' email: cravat@support.us name: OpenCRAVAT organization: KarchinLab website: null groups: [] has_logo: true hidden: false latest_version: 2.4.0 publish_time: '2018-10-26T20:50:29.000000' requires: - go size: 38837880 tags: - visualization title: Gene Ontology Summary type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.0.5 - 1.0.6 - 1.0.7 - 1.0.8 - 2.0.2 - 2.0.3 - 2.1.0 - 2.1.1 - 2.2.0 - 2.3.0 - 2.4.0 wggrasp: code_size: 7944 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.1.0: null 1.1.2: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.1.0: null 1.1.2: null datasource: null description: GRASP webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.2 publish_time: '2018-10-26T20:50:48.000000' requires: null size: 7944 tags: - visualization title: GRASP type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.1.0 - 1.1.2 wggtex: code_size: 13087 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 1.1.1: null 1.2.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 1.1.1: null 1.2.0: null datasource: null description: GTEx webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.2.0 publish_time: 2019-03-11T12:00:46.498740+0000 requires: null size: 13087 tags: - visualization title: GTEx type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 - 1.1.1 - 1.2.0 wggwas_catalog: code_size: 3327 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null 1.1.1: null 1.2.0: null data_versions: 1.0.0: null 1.1.0: null 1.1.1: null 1.2.0: null datasource: null description: GWAS Catalog webviewer widget developer: citation: '' email: kmoad@insilico.us.com name: Kyle Moad organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.2.0 publish_time: 2019-08-26T15:34:53.999669+0000 requires: null size: 3327 tags: - visualization title: GWAS Catalog type: webviewerwidget versions: - 1.0.0 - 1.1.0 - 1.1.1 - 1.2.0 wghaploreg_afr: code_size: 2064 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null 1.2.0: null data_versions: 1.0.0: null 1.1.0: null 1.2.0: null datasource: null description: Haploreg African information webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.2.0 publish_time: 2019-10-25T21:28:47.289373+0000 requires: null size: 2064 tags: - visualization title: Haploreg African type: webviewerwidget versions: - 1.0.0 - 1.1.0 - 1.2.0 wghaploreg_amr: code_size: 2066 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null 1.2.0: null data_versions: 1.0.0: null 1.1.0: null 1.2.0: null datasource: null description: Haploreg American information webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.2.0 publish_time: 2019-10-25T21:29:18.482192+0000 requires: null size: 2066 tags: - visualization title: Haploreg American type: webviewerwidget versions: - 1.0.0 - 1.1.0 - 1.2.0 wghaploreg_asn: code_size: 2091 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null 1.2.0: null data_versions: 1.0.0: null 1.1.0: null 1.2.0: null datasource: null description: Haploreg Asian information webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.2.0 publish_time: 2019-10-25T21:29:48.559944+0000 requires: null size: 2091 tags: - visualization title: Haploreg Asian type: webviewerwidget versions: - 1.0.0 - 1.1.0 - 1.2.0 wghaploreg_eur: code_size: 2097 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null 1.2.0: null data_versions: 1.0.0: null 1.1.0: null 1.2.0: null datasource: null description: Haploreg European information webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.2.0 publish_time: 2019-10-25T21:30:18.994356+0000 requires: null size: 2097 tags: - visualization title: Haploreg European type: webviewerwidget versions: - 1.0.0 - 1.1.0 - 1.2.0 wghaplotypes: code_size: 2280 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null datasource: null description: Haplotype information webviewer widget developer: citation: '' email: mary.a.wood.91@gmail.com name: Mary Wood organization: OHSU website: '' groups: [] has_logo: false hidden: true latest_version: 1.1.0 publish_time: 2019-05-06T20:20:30.324476+0000 requires: null size: 2280 tags: - visualization title: Haplotype Information type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 wghg19: code_size: 614 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null datasource: null description: hg19 info webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.3 publish_time: '2018-11-13T18:48:37.000000' requires: null size: 614 tags: - visualization title: hg19 info widget type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 wghgvs: code_size: 2133 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.2.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.2.0: null datasource: null description: HGVS webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.2.0 publish_time: '2018-10-26T20:51:08.000000' requires: null size: 2133 tags: - visualization title: HGVS type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.2.0 wghpo: code_size: 1326 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: InterPro webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.0.0 publish_time: 2021-06-10T18:37:39.052678+0000 requires: null size: 1326 tags: - visualization title: Human Phenotype Ontology type: webviewerwidget versions: - 1.0.0 wgigv: code_size: 4968979 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.1.0: null 1.2.0: null 1.2.1: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.1.0: null 1.2.0: null 1.2.1: null datasource: null description: igv.js integration into Open-CRAVAT developer: citation: "James T. Robinson, Helga Thorvaldsd\xF3ttir, Wendy Winckler, Mitchell\ \ Guttman, Eric S. Lander, Gad Getz, Jill P. Mesirov. Integrative Genomics Viewer.\ \ Nature Biotechnology 29, 24\u201326 (2011)\nHelga Thorvaldsd\xF3ttir, James\ \ T. Robinson, Jill P. Mesirov. Integrative Genomics Viewer (IGV): high-performance\ \ genomics data visualization and exploration. Briefings in Bioinformatics 14,\ \ 178-192 (2013)." email: support@opencravat.org name: OpenCRAVAT Developers organization: KarchinLab website: https://opencravat.org groups: [] has_logo: true hidden: false latest_version: 1.2.1 publish_time: '2018-11-13T21:20:38.000000' requires: null size: 4968979 tags: - visualization title: IGV type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.1.0 - 1.2.0 - 1.2.1 wgindel: code_size: 98328 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: Insertions and Deletions webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2021-03-01T15:11:48.027512+0000 requires: null size: 98328 tags: - visualization title: Insertions and Deletions type: webviewerwidget versions: - 1.0.0 - 1.1.0 wgintact: code_size: 24126 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null datasource: null description: IntAct webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.0 publish_time: '2019-01-08T21:38:13.000000' requires: null size: 24126 tags: - visualization title: IntAct type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.1.0 wginterpro: code_size: 130320 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 71.1.0: null 71.1.2: null 71.1.3: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 71.1.0: null 71.1.2: null 71.1.3: null datasource: null description: InterPro webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 71.1.3 publish_time: '2019-01-10T14:43:23.000000' requires: null size: 130320 tags: - visualization title: InterPro type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 - 71.1.0 - 71.1.2 - 71.1.3 wglinsight: code_size: 134816 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null datasource: null description: LINSIGHT webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.0 publish_time: '2018-10-26T20:51:29.000000' requires: null size: 134816 tags: - visualization title: LINSIGHT type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.1.0 wgloftool: code_size: 779 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null datasource: null description: LoFtool webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.2 publish_time: '2018-12-11T20:29:31.000000' requires: null size: 779 tags: - visualization title: LoFtool type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 wglollipop: code_size: 70336 commercial_warning: null data_size: 187535360 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 1.1.1: null 1.1.10: null 1.1.2: null 1.1.3: null 1.1.4: null 1.1.5: null 1.1.6: null 1.1.7: null 1.1.8: null 1.1.9: null 1.2.0: null 1.3.0: null 2.0.2: null 2.0.3: null 2.1.0: null 2.2.0: null 2.2.1: null 2.2.2: null 2.2.3: null data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.0.2: 1.0.0 1.1.0: 1.1.0 1.1.1: 1.1.0 1.1.10: 1.1.0 1.1.2: 1.1.0 1.1.3: 1.1.0 1.1.4: 1.1.0 1.1.5: 1.1.0 1.1.6: 1.1.0 1.1.7: 1.1.0 1.1.8: 1.1.0 1.1.9: 1.1.0 1.2.0: 1.1.0 1.3.0: 1.1.0 2.0.2: 1.1.0 2.0.3: 1.1.0 2.1.0: 2.1.0 2.2.0: 2.2.0 2.2.1: 2.2.0 2.2.2: 2.2.0 2.2.3: 2.2.0 datasource: null description: Protein diagram webviewer widget developer: citation: '' email: support@opencravat.org name: OpenCRAVAT Team organization: Karchinlab website: https://opencravat.org groups: [] has_logo: false hidden: true latest_version: 2.2.3 publish_time: '2018-11-14T22:12:07.000000' requires: null size: 187605696 tags: - visualization title: Protein diagram type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.1.5 - 1.1.6 - 1.1.7 - 1.1.8 - 1.1.9 - 1.1.10 - 1.2.0 - 1.3.0 - 2.0.2 - 2.0.3 - 2.1.0 - 2.2.0 - 2.2.1 - 2.2.2 - 2.2.3 wgmirbase: code_size: 1424 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: miRBase webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.0 publish_time: 2021-01-13T16:22:41.326180+0000 requires: null size: 1424 tags: - visualization title: miRBase type: webviewerwidget versions: - 1.0.0 wgmitomap: code_size: 1602 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: MITOMAP webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.0.0 publish_time: 2021-06-24T18:40:50.866491+0000 requires: null size: 1602 tags: - visualization title: MITOMAP type: webviewerwidget versions: - 1.0.0 wgmupit: code_size: 313385 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null datasource: null description: MuPIT webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.0 publish_time: '2018-10-26T20:51:53.000000' requires: null size: 313385 tags: - visualization title: MuPIT type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 wgmutation_assessor: code_size: 1409 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 1.2.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 1.2.0: null datasource: null description: Mutation Assessor webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.2.0 publish_time: '2018-11-26T19:33:16.000000' requires: null size: 1409 tags: - visualization title: Mutation Assessor type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 - 1.2.0 wgmutationsignature: code_size: 13034 commercial_warning: null data_size: 0 data_sources: 2.2.0: null data_versions: 2.2.0: null datasource: null description: Mutation Signature webviewer widget developer: citation: '' email: support@opencravat.org name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 2.2.0 publish_time: 2024-12-17T20:53:12.748586+0000 requires: - go size: 13034 tags: - visualization title: Mutation Signature type: webviewerwidget versions: - 2.2.0 wgmutationtaster: code_size: 1415 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: MutationTaster webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.0.0 publish_time: 2021-02-19T19:57:23.455769+0000 requires: null size: 1415 tags: - visualization title: MutationTaster type: webviewerwidget versions: - 1.0.0 wgmutpred1: code_size: 2104 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.0.6: null 1.1.0: null 1.1.2: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.0.6: null 1.1.0: null 1.1.2: null datasource: null description: MutPred webviewer widget developer: citation: '' email: '' name: '' organization: '' website: '' groups: [] has_logo: false hidden: true latest_version: 1.1.2 publish_time: '2018-11-28T16:34:00.000000' requires: null size: 2104 tags: - visualization title: MutPred type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.0.5 - 1.0.6 - 1.1.0 - 1.1.2 wgncbigene: code_size: 60991 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null datasource: null description: NCBI Gene webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.0 publish_time: 2019-05-06T20:23:02.251057+0000 requires: null size: 60991 tags: - visualization title: NCBI Gene type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 wgncrna: code_size: 50063 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null datasource: null description: Non-coding RNA webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.0 publish_time: '2018-10-26T20:53:07.000000' requires: null size: 50063 tags: - visualization title: Non-coding RNA diagram type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 wgndex: code_size: 841844 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.0.6: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.0.6: null 1.1.0: null datasource: null description: NDEx webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.0 publish_time: '2018-10-26T20:53:26.000000' requires: null size: 841844 tags: - visualization title: NDEx type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.0.5 - 1.0.6 - 1.1.0 wgndex_chd: code_size: 822702 commercial_warning: null data_size: 114688 data_sources: 1.0.0: null data_versions: 1.0.0: 1.0.0 datasource: null description: NDEx Webviewer Widget Congenital Heart Disease Pathways developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.0.0 publish_time: 2021-05-22T12:53:33.877863+0000 requires: null size: 937390 tags: - visualization title: NDEx CHD type: webviewerwidget versions: - 1.0.0 wgndex_chdsummary: code_size: 795044 commercial_warning: null data_size: 114688 data_sources: 1.0.1: null data_versions: 1.0.1: 1.0.1 datasource: null description: NDEx Congenital Heart Disease pathway enrichment summary webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.0.1 publish_time: 2020-09-22T18:12:47.917159+0000 requires: null size: 909732 tags: - visualization title: NDEx Congenital Heart Disease Pathway Enrichment Summary type: webviewerwidget versions: - 1.0.1 wgndex_signor: code_size: 822644 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: NDEx Webviewer Widget SIGNOR Pathways developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.0.0 publish_time: 2021-05-23T15:32:23.722407+0000 requires: null size: 822644 tags: - visualization title: NDEx SIGNOR type: webviewerwidget versions: - 1.0.0 wgndex_signorsummary: code_size: 814389 commercial_warning: null data_size: 102400 data_sources: 1.0.2: null data_versions: 1.0.2: 1.0.2 datasource: null description: NDEx Signor pathway enrichment summary webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.0.2 publish_time: 2020-09-22T18:13:39.706854+0000 requires: null size: 916789 tags: - visualization title: NDEx Signor Pathway Enrichment Summary type: webviewerwidget versions: - 1.0.2 wgndexchasmplussummary: code_size: 5361055 commercial_warning: null data_size: 109242 data_sources: 1.0.0: null 1.0.1: null 1.0.10: null 1.0.12: null 1.0.13: null 1.0.14: null 1.0.15: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.0.6: null 1.0.8: null 1.0.9: null 1.1.0: null 1.1.1: null data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.0.10: 1.0.0 1.0.12: 1.0.0 1.0.13: 1.0.0 1.0.14: 1.0.0 1.0.15: 1.0.0 1.0.2: 1.0.0 1.0.3: 1.0.0 1.0.4: 1.0.0 1.0.5: 1.0.0 1.0.6: 1.0.0 1.0.8: 1.0.0 1.0.9: 1.0.0 1.1.0: 1.0.0 1.1.1: 1.0.0 datasource: null description: NDEX Enriched Cancer Pathways widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.1.1 publish_time: '2018-09-26T01:40:59.000000' requires: null size: 5470297 tags: - visualization title: Cancer Pathways Enriched for CHASMplus Drivers (NDEx) type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.0.5 - 1.0.6 - 1.0.8 - 1.0.9 - 1.0.10 - 1.0.12 - 1.0.13 - 1.0.14 - 1.0.15 - 1.1.0 - 1.1.1 wgndexsummary: code_size: 810207 commercial_warning: null data_size: 590848 data_sources: 1.0.1: null data_versions: 1.0.1: 1.0.1 datasource: null description: NDEx enrichment summary webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.0.1 publish_time: 2020-09-22T18:11:56.079742+0000 requires: null size: 1401055 tags: - visualization title: NDEx NCI Cancer Pathway Enrichment Summary type: webviewerwidget versions: - 1.0.1 wgndexvestsummary: code_size: 5360369 commercial_warning: null data_size: 109242 data_sources: 1.0.0: null 1.0.1: null 1.0.10: null 1.0.11: null 1.0.12: null 1.0.13: null 1.0.14: null 1.0.2: null 1.0.3: null 1.0.4: null 1.0.5: null 1.0.6: null 1.0.7: null 1.0.9: null 1.1.0: null 1.1.1: null data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.0.10: 1.0.0 1.0.11: 1.0.0 1.0.12: 1.0.0 1.0.13: 1.0.0 1.0.14: 1.0.0 1.0.2: 1.0.0 1.0.3: 1.0.0 1.0.4: 1.0.0 1.0.5: 1.0.0 1.0.6: 1.0.0 1.0.7: 1.0.0 1.0.9: 1.0.0 1.1.0: 1.0.0 1.1.1: 1.0.0 datasource: null description: NDEX Enriched Pathogentic Pathways widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.1.1 publish_time: '2018-09-26T01:41:16.000000' requires: null size: 5469611 tags: - visualization title: NDEX Enriched Pathogentic Pathways type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.0.5 - 1.0.6 - 1.0.7 - 1.0.9 - 1.0.10 - 1.0.11 - 1.0.12 - 1.0.13 - 1.0.14 - 1.1.0 - 1.1.1 wgnote: code_size: 5447 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 2.0.2: null 3.0.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 2.0.2: null 3.0.0: null datasource: null description: Note-taking widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 3.0.0 publish_time: '2019-01-12T16:58:39.000000' requires: null size: 5447 tags: - visualization title: Note type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 2.0.2 - 3.0.0 wgomim: code_size: 1107 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: OMIM webviewer widget developer: citation: '' email: kmoad@insilico.us.com name: Kyle Moad organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.0 publish_time: 2020-09-14T19:57:52.332038+0000 requires: null size: 1107 tags: - visualization title: OMIM type: webviewerwidget versions: - 1.0.0 wgoncokb: code_size: 13046 commercial_warning: null data_size: 0 data_sources: 1.0.1: null data_versions: 1.0.1: null datasource: null description: OncoKB webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.1 publish_time: 2021-12-30T19:09:40.834414+0000 requires: null size: 13046 tags: - visualization title: OncoKB type: webviewerwidget versions: - 1.0.1 wgpangalodb: code_size: 1902 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: PangaloDB webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.0 publish_time: 2021-06-24T18:40:50.878529+0000 requires: null size: 1902 tags: - visualization title: PangaloDB type: webviewerwidget versions: - 1.0.0 wgpharmgkb: code_size: 4491 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null 2.0.0: null 2.0.1: null data_versions: 1.0.0: null 1.1.0: null 2.0.0: null 2.0.1: null datasource: null description: PharmGKB webviewer widget developer: citation: '' email: kmoad@insilico.us.com name: Kyle Moad organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 2.0.1 publish_time: 2019-09-30T19:48:42.874848+0000 requires: null size: 4491 tags: - visualization title: PharmGKB type: webviewerwidget versions: - 1.0.0 - 1.1.0 - 2.0.0 - 2.0.1 wgphastcons: code_size: 1392 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null 1.1.1: null 1.2.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null 1.1.1: null 1.2.0: null datasource: null description: phastCons web viewer widget developer: citation: '' email: support@opencravat.org name: OpenCRAVAT Team organization: KarchinLab website: https://opencravat.org groups: [] has_logo: false hidden: true latest_version: 1.2.0 publish_time: '2018-11-26T19:53:49.000000' requires: null size: 1392 tags: - visualization title: Phast Cons type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.1.0 - 1.1.1 - 1.2.0 wgphdsnpg: code_size: 7856 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null datasource: null description: PhDSNPg developer: citation: '' email: support@opencravat.org name: Kyle Moad organization: In Silico Solutions website: '' groups: [] has_logo: true hidden: true latest_version: 1.1.0 publish_time: '2018-10-26T20:53:55.000000' requires: null size: 7856 tags: - visualization title: PhDSNPg type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.1.0 wgphi: code_size: 601 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null datasource: null description: P(HI) webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.2 publish_time: '2019-01-08T21:39:02.000000' requires: null size: 601 tags: - visualization title: P(HI) type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 wgphylop: code_size: 1834 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null 1.1.1: null 1.2.1: null 1.3.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null 1.1.1: null 1.2.1: null 1.3.0: null datasource: null description: PhyloP webviewer widget developer: citation: '' email: support@opencravat.org name: OpenCRAVAT Team organization: KarchinLab website: https://opencravat.org groups: [] has_logo: false hidden: false latest_version: 1.3.0 publish_time: '2019-01-03T20:32:39.000000' requires: null size: 1834 tags: - visualization title: PhyloP type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.1.0 - 1.1.1 - 1.2.1 - 1.3.0 wgpolyphen2: code_size: 55244 commercial_warning: null data_size: 0 data_sources: 1.1.2: null data_versions: 1.1.2: null datasource: null description: Polyphen2 webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.2 publish_time: 2021-01-19T16:41:41.539256+0000 requires: null size: 55244 tags: - visualization title: Polyphen2 type: webviewerwidget versions: - 1.1.2 wgprec: code_size: 807 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null datasource: null description: P(rec) webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.1.0 publish_time: '2019-01-08T21:39:35.000000' requires: null size: 807 tags: - visualization title: P(rec) type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 wgprimateai: code_size: 1868 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: PrimateAI webviewer widget developer: citation: '' email: cravat@support.us name: OpenCRAVAT organization: KarchinLab website: null groups: [] has_logo: false hidden: false latest_version: 1.0.0 publish_time: 2025-02-06T21:25:54.147642+0000 requires: null size: 1868 tags: - visualization title: PrimateAI type: webviewerwidget versions: - 1.0.0 wgprovean: code_size: 1281 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: PROVEAN webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.0.0 publish_time: 2021-02-19T19:58:29.931796+0000 requires: null size: 1281 tags: - visualization title: PROVEAN type: webviewerwidget versions: - 1.0.0 wgpseudogene: code_size: 13006 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null datasource: null description: Pseudogene webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.0 publish_time: '2018-10-26T20:54:52.000000' requires: null size: 13006 tags: - visualization title: Pseudogene type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 wgpubmed: code_size: 29575 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null datasource: null description: PubMed webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.0 publish_time: 2019-05-06T20:25:18.796147+0000 requires: null size: 29575 tags: - visualization title: PubMed type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 wgrankscore: code_size: 72068 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null datasource: null description: Rank Score Comparison webviewer widget developer: citation: '' email: support@opencravat.org name: OpenCRAVAT Team organization: KarchinLab website: https://opencravat.org groups: [] has_logo: true hidden: false latest_version: 1.1.0 publish_time: 2021-03-02T14:33:35.751900+0000 requires: null size: 72068 tags: - visualization title: Rank Score Comparison type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 wgrevel: code_size: 35635 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 1.2.0: null 1.2.1: null 1.3.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 1.2.0: null 1.2.1: null 1.3.0: null datasource: null description: REVEL webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: false latest_version: 1.3.0 publish_time: '2018-10-26T20:55:49.000000' requires: null size: 35635 tags: - visualization title: REVEL type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 - 1.2.0 - 1.2.1 - 1.3.0 wgrvis: code_size: 1115 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null datasource: null description: RVIS webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.1.0 publish_time: '2019-01-09T16:07:12.000000' requires: null size: 1115 tags: - visualization title: RVIS type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 wgsift: code_size: 2037 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: SIFT webviewer widget developer: citation: '' email: support@opencravat.org name: OpenCRAVAT Team organization: KarchinLab website: https://opencravat.org groups: [] has_logo: false hidden: true latest_version: 1.1.0 publish_time: 2021-06-24T18:40:50.909965+0000 requires: null size: 2037 tags: - visualization title: SIFT type: webviewerwidget versions: - 1.0.0 - 1.1.0 wgsiphy: code_size: 1523 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.1.0: null 1.1.1: null data_versions: 1.0.0: null 1.0.1: null 1.1.0: null 1.1.1: null datasource: null description: SiPhy webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.1.1 publish_time: 2019-05-06T20:26:19.430462+0000 requires: null size: 1523 tags: - visualization title: SiPhy type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.1.0 - 1.1.1 wgsosamplesummary: code_size: 11992 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null 1.1.1: null 1.1.2: null 1.1.3: null 1.1.4: null 1.1.5: null 1.1.6: null 1.1.7: null 1.1.8: null 1.2.1: null 1.2.2: null 1.2.3: null 1.3.0: null 2.0.2: null 2.1.0: null 2.2.0: null data_versions: 1.0.0: null 1.1.0: null 1.1.1: null 1.1.2: null 1.1.3: null 1.1.4: null 1.1.5: null 1.1.6: null 1.1.7: null 1.1.8: null 1.2.1: null 1.2.2: null 1.2.3: null 1.3.0: null 2.0.2: null 2.1.0: null 2.2.0: null datasource: null description: Sequence Ontology Sample Summary webviewer widget developer: citation: '' email: cravat@support.us name: OpenCRAVAT organization: KarchinLab website: null groups: [] has_logo: false hidden: false latest_version: 2.2.0 publish_time: '2018-09-26T01:41:46.000000' requires: null size: 11992 tags: - visualization title: Sequence Ontology Sample Summary type: webviewerwidget versions: - 1.0.0 - 1.1.0 - 1.1.1 - 1.1.2 - 1.1.3 - 1.1.4 - 1.1.5 - 1.1.6 - 1.1.7 - 1.1.8 - 1.2.1 - 1.2.2 - 1.2.3 - 1.3.0 - 2.0.2 - 2.1.0 - 2.2.0 wgsosummary: code_size: 4356 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 1.1.2: null 1.1.3: null 1.2.0: null 1.2.1: null 1.3.0: null 1.4.0: null 1.5.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null 1.1.2: null 1.1.3: null 1.2.0: null 1.2.1: null 1.3.0: null 1.4.0: null 1.5.0: null datasource: null description: Sequence Ontology Summary result viewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.5.0 publish_time: '2018-09-26T01:41:51.000000' requires: null size: 4356 tags: - visualization title: Sequence Ontology Summary type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 - 1.1.2 - 1.1.3 - 1.2.0 - 1.2.1 - 1.3.0 - 1.4.0 - 1.5.0 wgswissprot_binding: code_size: 1858 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null data_versions: 1.0.0: null 1.0.1: null datasource: null description: Swiss-Prot Binding webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.1 publish_time: 2021-01-05T19:07:21.132077+0000 requires: null size: 1858 tags: - visualization title: Swiss-Prot Binding type: webviewerwidget versions: - 1.0.0 - 1.0.1 wgswissprot_domains: code_size: 1494 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null data_versions: 1.0.0: null 1.0.1: null datasource: null description: Swiss-Prot Domains webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.1 publish_time: 2021-01-05T19:09:08.056555+0000 requires: null size: 1494 tags: - visualization title: Swiss-Prot Domains type: webviewerwidget versions: - 1.0.0 - 1.0.1 wgswissprot_ptm: code_size: 1922 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.1: null data_versions: 1.0.0: null 1.1.1: null datasource: null description: Swiss-Prot PTM webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.1.1 publish_time: 2020-09-15T22:10:23.410746+0000 requires: null size: 1922 tags: - visualization title: Swiss-Prot PTM type: webviewerwidget versions: - 1.0.0 - 1.1.1 wgtarget: code_size: 63541 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null datasource: null description: Target webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.0 publish_time: 2019-05-06T20:27:05.179368+0000 requires: null size: 63541 tags: - visualization title: Target type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 wgthousandgenomes: code_size: 24174 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.1.0: null datasource: null description: 1000 genomes webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.0 publish_time: 2019-05-06T20:27:21.302904+0000 requires: null size: 24174 tags: - visualization title: 1000 Genomes type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.1.0 wgthousandgenomes_ad_mixed_american: code_size: 1357 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: 1000 genomes webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.1.0 publish_time: 2021-01-13T17:54:36.175610+0000 requires: null size: 1357 tags: - visualization title: 1000 Genomes-Ad Mixed American type: webviewerwidget versions: - 1.0.0 - 1.1.0 wgthousandgenomes_african: code_size: 1621 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: 1000 genomes webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.1.0 publish_time: 2021-01-13T17:54:36.186767+0000 requires: null size: 1621 tags: - visualization title: 1000 Genomes-African type: webviewerwidget versions: - 1.0.0 - 1.1.0 wgthousandgenomes_east_asian: code_size: 1410 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: 1000 genomes webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.1.0 publish_time: 2021-01-13T17:54:36.196641+0000 requires: null size: 1410 tags: - visualization title: 1000 Genomes-East Asian type: webviewerwidget versions: - 1.0.0 - 1.1.0 wgthousandgenomes_european: code_size: 1392 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: 1000 genomes webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.1.0 publish_time: 2021-01-13T17:54:36.207269+0000 requires: null size: 1392 tags: - visualization title: 1000 Genomes-European type: webviewerwidget versions: - 1.0.0 - 1.1.0 wgthousandgenomes_south_asian: code_size: 1419 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.1.0: null data_versions: 1.0.0: null 1.1.0: null datasource: null description: 1000 genomes webviewer widget developer: citation: '' email: mlarsen@insilico.us.com name: Madison Larsen organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: false latest_version: 1.1.0 publish_time: 2021-01-13T17:54:36.217555+0000 requires: null size: 1419 tags: - visualization title: 1000 Genomes-South Asian type: webviewerwidget versions: - 1.0.0 - 1.1.0 wgtopgeneschasmplussummary: code_size: 3087 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.1.0: null datasource: null description: Top Genes CHSAMplus Summary webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.1.0 publish_time: '2018-10-16T18:07:44.000000' requires: null size: 3087 tags: - visualization title: Top Genes CHASMplus Summary type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.1.0 wgtopgenessummary: code_size: 19861 commercial_warning: null data_size: 619520 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.2.0: null 2.0.2: null 2.1.0: null 2.2.0: null 2.2.1: null 2.3.0: null 2.3.1: null data_versions: 1.0.0: 1.0.0 1.0.1: 1.0.0 1.0.2: 1.0.0 1.0.3: 1.0.0 1.0.4: 1.0.0 1.2.0: 1.0.0 2.0.2: 1.0.0 2.1.0: 2.1.0 2.2.0: 2.1.0 2.2.1: 2.1.0 2.3.0: 2.1.0 2.3.1: 2.1.0 datasource: null description: Top Genes Summary webviewer widget developer: citation: '' email: cravat@support.us name: OpenCRAVAT organization: KarchinLab website: null groups: [] has_logo: true hidden: false latest_version: 2.3.1 publish_time: '2018-09-26T01:42:15.000000' requires: null size: 639381 tags: - visualization title: Recurrently Mutated Genes type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.2.0 - 2.0.2 - 2.1.0 - 2.2.0 - 2.2.1 - 2.3.0 - 2.3.1 wgtopgenesvestsummary: code_size: 3056 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.1.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.0.4: null 1.1.0: null datasource: null description: Top Genes VEST Summary webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.1.0 publish_time: '2018-10-16T18:07:59.000000' requires: null size: 3056 tags: - visualization title: Top Genes VEST Summary type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.0.4 - 1.1.0 wguk10k_cohort: code_size: 52341 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.1.0: null 1.1.1: null data_versions: 1.0.0: null 1.0.1: null 1.1.0: null 1.1.1: null datasource: null description: UK10K Cohort webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.1.1 publish_time: 2019-05-06T20:27:52.817920+0000 requires: null size: 52341 tags: - visualization title: UK10K Cohort type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.1.0 - 1.1.1 wgvarity_r: code_size: 1847 commercial_warning: null data_size: 0 data_sources: 1.0.0: null data_versions: 1.0.0: null datasource: null description: VARITY_R webviewer widget developer: citation: '' email: support@opencravat.org name: OpenCRAVAT organization: KarchinLab website: null groups: [] has_logo: false hidden: false latest_version: 1.0.0 publish_time: 2025-02-23T21:11:18.734046+0000 requires: null size: 1847 tags: - visualization title: VARITY_R type: webviewerwidget versions: - 1.0.0 wgvcfinfo: code_size: 910 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null datasource: null description: VCF info webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: false hidden: true latest_version: 1.0.3 publish_time: '2018-11-13T18:45:14.000000' requires: null size: 910 tags: - visualization title: VCF info widget type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 wgvest: code_size: 165178 commercial_warning: null data_size: 0 data_sources: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null 1.2.0: null 1.3.0: null data_versions: 1.0.0: null 1.0.1: null 1.0.2: null 1.0.3: null 1.1.0: null 1.2.0: null 1.3.0: null datasource: null description: VEST webviewer widget developer: citation: '' email: rkim@insilico.us.com name: Rick Kim organization: In Silico Solutions website: http://www.insilico.us.com groups: [] has_logo: true hidden: true latest_version: 1.3.0 publish_time: '2018-10-29T20:25:54.000000' requires: null size: 165178 tags: - visualization title: VEST type: webviewerwidget versions: - 1.0.0 - 1.0.1 - 1.0.2 - 1.0.3 - 1.1.0 - 1.2.0 - 1.3.0